Protein transpor natrium-glukosa: Perbedaan antara revisi
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{{infobox protein
'''Transporter natrium glukosa''' ({{lang-en|Sodium-dependent glucose cotransporters}}) adalah [[permease]] kerabat [[transporter glukosa]] yang terdapat pada lapisan mukosa pada [[usus halus]] dan [[tubulus proksimal]], yang berperan dalam proses penyerapan ulang [[glukosa]] dalam [[ginjal]].▼
| Name = famili pengangkut zat terlarut 5 (kotransporter natrium/glukosa), anggota 1
| caption =
| image =
| width =
| HGNCid = 11036
| Symbol = [[SLC5A1]]
| AltSymbols = SGLT1
| EntrezGene = 6523
| OMIM = 182380
| RefSeq = NM_000343
| UniProt = P13866
| PDB =
| ECnumber =
| Chromosome = 22
| Arm = q
| Band = 13.1
| LocusSupplementaryData =
}}
{{infobox protein
| Name = famili pengangkut zat terlarut 5 (kotransporter natrium/glukosa), anggota 2
| caption =
| image =
| width =
| HGNCid = 11037
| Symbol = [[SLC5A2]]
| AltSymbols = SGLT2
| EntrezGene = 6524
| OMIM = 182381
| RefSeq = NM_003041
| UniProt = P31639
| PDB =
| ECnumber =
| Chromosome = 16
| Arm = p
| Band = 11.2
| LocusSupplementaryData =
}}
{{infobox protein
| Name = famili pengangkut zat terlarut 5 (kotransporter glukosa afinitas rendah), anggota 4
| caption =
| image =
| width =
| HGNCid = 11039
| Symbol = [[SLC5A4]]
| AltSymbols = SGLT3, SAAT1, DJ90G24.4
| EntrezGene = 6527
| OMIM =
| RefSeq = NM_014227
| UniProt = Q9NY91
| PDB =
| ECnumber =
| Chromosome = 22
| Arm = q
| Band = 12.1-12.3
| LocusSupplementaryData =
}}
▲'''
== SGLT1 ==
SGLT1 ({{lang-en|Sodium/glucose cotransporter 1, Na<sup>+</sup>/glucose cotransporter 1, High affinity sodium-glucose cotransporter, Intestinal sodium-glucose cotransporter, D22S675, SLC5A1, NAGT, SGLT1}}) merupakan SGLT dengan panjang 644 AA dengan ekspresi pada [[usus]], [[ginjal]],<ref name="P13866">{{en}} {{cite web
| url = http://www.uniprot.org/uniprot/P13866
| title = Reviewed, UniProtKB/Swiss-Prot P13866 (SC5A1_HUMAN)
| accessdate = 2010-05-07
| work = UniProt
}}</ref> dan ''cardiac myocyte sarcolemma''.<ref name="PM19509029">{{en}} {{cite web
| url = http://www.ncbi.nlm.nih.gov/pubmed/19509029
| title = SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states
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SGLT2 ({{lang-en|Sodium/glucose cotransporter 2, Na<sup>+</sup>/glucose cotransporter 2, Low affinity sodium-glucose cotransporter, SLC5A2, SGLT2}}) merupakan [[glikoprotein]] dengan panjang 672 AA yang tergolong permease [[transporter glukosa]].
Mutasi pada SLC5A2 menyebabkan [[glukosuria]] pada [[ginjal]]<ref>{{en}} {{cite web
| url = http://www.uniprot.org/uniprot/P31639
| title = Reviewed, UniProtKB/Swiss-Prot P31639 (SC5A2_HUMAN)
| accessdate = 2010-05-08
| work = UniProt
}}</ref> dan [[aminoasiduria]].<ref>{{en}} {{cite web
| url = http://www.ncbi.nlm.nih.gov/pubmed/15610225
| title = A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria.
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}}</ref>
[[Tioglikosida]] merupakan inhibitors SGLT1 dan SGLT2, dan berpotensi mengontrol [[hiperglisemia]] pada penderita diabetes.<ref>{{en}} {{cite web
| url = http://www.ncbi.nlm.nih.gov/pubmed/17505558
| title = Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.
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[[Kategori:Biologi sel]]
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