KCNK3: Perbedaan antara revisi

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'''''Potassium channel subfamily K member 3''''' adalah [[protein]] yang disandikan oleh [[gen]] ''KCNK3'' dalam tubuh manusia.<ref name="pmid9312005">{{cite journal |vauthors=Duprat F, Lesage F, Fink M, Reyes R, Heurteaux C, Lazdunski M | title = TASK, a human background K+ channel to sense external pH variations near physiological pH | journal = EMBO J | volume = 16 | issue = 17 | pages = 5464–71 |date=Dec 1997 | pmid = 9312005 | pmc = 1170177 | doi = 10.1093/emboj/16.17.5464 }}</ref><ref name="pmid9721223">{{cite journal |vauthors=Lesage F, Lazdunski M | title = Mapping of human potassium channel genes TREK-1 (KCNK2) and TASK (KCNK3) to chromosomes 1q41 and 2p23 | journal = Genomics | volume = 51 | issue = 3 | pages = 478–9 |date=Oct 1998 | pmid = 9721223 | pmc = | doi = 10.1006/geno.1998.5397 }}</ref><ref name="pmid16382106">{{cite journal |vauthors=Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S | title = International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels | journal = Pharmacol Rev | volume = 57 | issue = 4 | pages = 527–40 |date=Dec 2005 | pmid = 16382106 | pmc = | doi = 10.1124/pr.57.4.12 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: KCNK3 potassium channel, subfamily K, member 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3777| accessdate = }}</ref> KCNK3 diketahui telah berinteraksi dengan [[YWHAB]]<ref name=pmid12437930>{{cite journal |doi=10.1016/S0092-8674(02)01040-1 |last=O'Kelly |first=Ita |author2=Butler Margaret H |author3=Zilberberg Noam |author4=Goldstein Steve A N |date=Nov 2002 |title=Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals |journal=Cell |volume=111 |issue=4 |pages=577–88 |location = United States| issn = 0092-8674| pmid = 12437930 }}</ref> dan [[S100A10]].<ref name=pmid12198146>{{cite journal |doi=10.1093/emboj/cdf469 |last=Girard |first=Christophe |author2=Tinel Norbert |author3=Terrenoire Cécile |author4=Romey Georges |author5=Lazdunski Michel |author6=Borsotto Marc |date=Sep 2002 |title=p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1 |journal=EMBO J. |volume=21 |issue=17 |pages=4439–48 |location = England| issn = 0261-4189| pmid = 12198146 |pmc=125412 }}</ref>
 
Beberapa mutasi terhadap gen ini telah ditemukan oleh para peneliti. Salah satunya adalah mutasi yang dapat menyebabkan [[hipertensi paru]],.<ref name="Ma 2013">{{cite journal|author=Ma L, Roman-Campos D, Austin ED. |linkurl=http://www.nejm.org/doi/full/10.1056/NEJMoa1211097#t=abstract |title=A novel channelopathy in pulmonary arterial hypertension |lang=en |journal=N Engl J Med. |year=2013 |issue=369 |page=351-361 |pmid=}}</ref>
 
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