Varian Kappa SARS-CoV-2: Perbedaan antara revisi
Konten dihapus Konten ditambahkan
pengembangan artikel |
Rescuing 0 sources and tagging 1 as dead.) #IABot (v2.0.8.6 |
||
| (3 revisi perantara oleh 3 pengguna tidak ditampilkan) | |||
Baris 62:
| || D377Y
|- style="font-size: smaller; text-align: left;" class="sortbottom"
| colspan="3" | Sumber: CoVariants,<ref name="CoVariants">{{cite web |url=https://covariants.org/variants/21B.Kappa |title=Variant: 21B (Kappa) |date=30 Juni 2021 |work=CoVariants |access-date=6 Juli 2021 |language=en}}</ref>
|- style="font-size: smaller; text-align: left;" class="sortbottom"
| colspan="3" | Catatan: N501Y berarti perubahan dari [[asparagina]] (N) menjadi [[tirosina]] (Y) pada posisi [[asam amino]] 501.<ref>Untuk daftar simbol asam amino α yang dipakai dalam protein sesuai arahan RNA duta, lihat ini: {{cite web |url=http://www.chem.qmul.ac.uk/iupac/AminoAcid/AA1n2.html |title=Nomenclature and Symbolism for Amino Acids and Peptides |year=1983 |publisher=IUPAC-IUB Joint Commission on Biochemical Nomenclature |access-date=5 Maret 2018 |archive-url=https://web.archive.org/web/20081009023202/http://www.chem.qmul.ac.uk/iupac/AminoAcid/AA1n2.html |archive-date=9 Oktober 2008 |url-status=dead |language=en}}</ref>
Baris 72:
Mutasi L452R menguatkan afinitas protein bulir terhadap reseptor ACE2 sehingga mengurangi kemampuan sistem kekebalan tubuh untuk mengenalinya.<ref>{{cite journal |last1=Starr |first1=Tyler N. |last2=Greaney |first2=Allison J. |last3=Dingens |first3=Adam S. |last4=Bloom |first4=Jesse D. |date=April 2021 |title=Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016 |journal=Cell Reports Medicine |volume=2 |issue=4 |pages=100255 |doi=10.1016/j.xcrm.2021.100255 |doi-access=free |language=en}}</ref><ref>{{cite journal |last1=Zhang |first1=Wenjuan |last2=Davis |first2=Brian D. |last3=Chen |first3=Stephanie S. |last4=Sincuir Martinez |first4=Jorge M. |last5=Plummer |first5=Jasmine T. |last6=Vail |first6=Eric |date=6 April 2021 |title=Emergence of a Novel SARS-CoV-2 Variant in Southern California |journal=JAMA |volume=325 |issue=13 |pp=1324–1326 |pmc=7879386 |pmc-embargo-date=11 Agustus 2021 |doi=10.1001/jama.2021.1612 |doi-access=free |language=en}}</ref> Mutasi E484Q menguatkan potensi terikat dengan ACE2 dan meningkatkan kemampuan menghindar dari sistem kekebalan tubuh.<ref>{{cite news |last=Haseltine |first=William |date=12 April 2021 |title=An Indian SARS-CoV-2 Variant Lands In California. More Danger Ahead? |work=Forbes |url=https://www.forbes.com/sites/williamhaseltine/2021/04/12/an-indian-sars-cov-2-variant-lands-in-california-more-danger-ahead/?sh=1ff3056b3b29 |access-date=7 Juni 2021 |language=en}}</ref><ref>{{cite journal |last1=Harvey |first1=WT |last2=Carabelli |first2=AM |last3=Jackson |first3=B |last4=Gupta |first4=RK |last5=Thomson |first5=EC |last6=Harrison |first6=EM |last7=Ludden |first7=C |last8=Reeve |first8=R |last9=Rambaut |first9=A |last10=Peacock |first10=SJ |last11=Robertson |first11=DL |display-authors=6 |date=1 Juni 2021 |title=SARS-CoV-2 variants, spike mutations and immune escape |journal=Nature Reviews Microbiology |volume=19 |pages=409–424 |doi=10.1038/s41579-021-00573-0 |quote=''For example, recently detected viruses of lineage B.1.617.1 were anticipated to show altered antigenicity due to the presence of the substitutions L452R and E484Q, which have been described as affecting antibody recognition.'' |language=en}}</ref>
==
{| class="dapat diurutkan menurut wiki"
! colspan="3" |Kasus menurut negara (Diperbarui per 7 Juli 2021) GISAID<ref>{{Cite web|title=GISAID - Varian hCov19|url=https://www.gisaid.org/hcov19-variants/| access-date=2021-07-07|website=www.gisaid.org}}</ref>
|-
! scope="col" |Negara
! scope="col" |Kasus yang dikonfirmasi
! scope="col" |Tanggal koleksi
|-
|India
|3,693
|26 Mei 2021
|-
|Britania Raya
|517
|31 Mei 2021
|-
|AS
|299
|24 Juni 2021
|-
|Kanada
|266
|12 Mei 2021
|-
|Irlandia
|170
|8 Juni 2021
|-
|Australia
|112
|15 Juni 2021
|-
|Jerman
|106
|22 Juni 2021
|-
|Singapura
|59
|13 Mei 2021
|-
|Denmark
|28
|31 Mei 2021
|-
|Belanda
|27
|12 Juni 2021
|-
|Jepang
|27
|7 Mei 2021
|-
|Angola
|24
|20 April 2021
|-
|Prancis
|16
|20 Mei 2021
|-
| Belgia
|16
|13 Mei 2021
|-
|Cina
|13
|18 April 2021
|-
|Qatar
|12
|17 Mei 2021
|-
|Korea Selatan
|12
|27 April 2021
|-
|Swiss
|10
|4 Mei 2021
|-
|Portugal
|9
|4 Mei 2021
|-
|Italia
|9
|24 Mei 2021
|-
|Bahrain
|8
|10 April 2021
|-
|Meksiko
|8
|2 Juni 2021
|-
|Afrika Selatan
|8
|18 Juni 2021
|-
|Finlandia
|7
|23 Mei 2021
|-
|Luksemburg
|6
|26 April 2021
|-
|Spanyol
|5
|19 Mei 2021
|-
|Swedia
|5
|17 April 2021
|-
|Ghana
|5
|20 April 2021
|-
|Kenya
|5
|29 April 2021
|-
|Republik Ceko
|4
|4 Mei 2021
|-
|Yordania
|4
|25 April 2021
|-
|Myanmar
|4
|2 Juni 2021
|-
|Selandia Baru
|4
|8 April 2021
|-
|Malaysia
|4
|1 Juni 2021
|-
|Indonesia
|3
|29 April 2021
|-
|Guadeloupe
|2
|10 Maret 2021
|-
|Malawi
|2
|30 April 2021
|-
|Nepal
|2
|9 Mei 2021
|-
|Sint Maarten
|2
|3 April 2021
|-
|Botswana
|2
|1 Juni 2021
|-
|Kuwait
| 1
|
|-
|Austria
| 1
|
|-
|Kamboja
| 1
|5 April 2021
|-
|Curaçao
| 1
|23 April 2021
|-
|Yunani
| 1
|6 April 2021
|-
|Slovakia
| 1
|19 April 2021
|-
|Slovenia
| 1
|6 April 2021
|-
|Thailand
| 1
|26 April 2021
|-
|Uganda
| 1
|26 Maret 2021
|-
|Zambia
| 1
|2 Mei 2021
|-
|Dunia (50 negara)
|Jumlah: '''5,525'''
|<small>Total per 1 Juli 2021</small>
|}
== Penyebaran ==
Baris 99 ⟶ 310:
{{scholia}}
* {{en}} [https://www.gov.uk/government/publications/covid-19-variants-genomically-confirmed-case-numbers/variants-distribution-of-cases-data#Variant11 Public Health England: Variants of concern or under investigation, B.1.617]
* {{en}} [https://cov-lineages.org/global_report_B.1.617.1.html Garis keturunan PANGO: Laporan Varian Baru - Laporan persebaran global garis keturunan B.1.617.1]{{Pranala mati|date=Maret 2022 |bot=InternetArchiveBot |fix-attempted=yes }}
* {{en}} [https://www.gisaid.org/hcov19-variants/ Pangkalan data pengurutan GISAID - Pelacakan varian Covid-19]
{{portal bar|Penyakit koronavirus 2019|Kedokteran|Virus}}
{{COVID-19
{{authority control}}
| |||