Kromosom 6: Perbedaan antara revisi

[[Berkas:Human male karyotpe high resolution - Chromosome 6 cropped.png|jmpl|Kromosom 6 pada manusia setelah [[G banding|G-banding]]. <br/> Satu dari ibu, satu dari ayah.]]

'''Kromosom 6''' adalah salah satu dari 23 pasang [[kromosom]] pada [[manusia]]. Seorang manusia biasanya memiliki dua salinan kromosom ini. Kromosom 6 mencakup lebih dari 170 juta [[pasangan basa]] (bahan pembangun [[DNA]]) dan mewakili antara 5,5 hingga 6% dari total DNA dalam [[sel (biologi)|sel]]. Kromosom 6 berisi [[kompleks histokompatibilitas utama]] yang terdiri dari 100 gen lebih yang terkait dengan respons imun (respons kolektif dan terkoordinasi dari sistem imun tubuh terhadap pengenalan zat asing) dan berperan penting dalam [[transplantasi organ]].

 

== Gen ==

 

=== Jumlah gen ===

Pada 2003, keseluruhan kromosom 6 dianotasi secara manual untuk protein, menghasilkan identifikasi 1.557 gen dan 633 [[pseudogen]].<ref>{{cite journal |vauthors = Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S|display-authors = 6 |title=The DNA sequence and analysis of human chromosome 6 |journal=Nature |volume=425 |issue=6960 |pages=805–11 |date=October 2003 |pmid=14574404 |doi=10.1038/nature02055 |doi-access=free |bibcode=2003Natur.425..805M }}</ref>

 

 

{| class="wikitable" style="text-align:right"

! Tanggal

|-

|style="text-align:center"| <ref name="CCDS">{{cite web | title=Search results - 6&#91;CHR&#93; AND "Homo sapiens"&#91;Organism&#93; AND ("has ccds"&#91;Properties&#93; AND alive&#91;prop&#93;) - Gene | website= NCBI |version = CCDS Release 20 for ''Homo sapiens'' | url=https://www.ncbi.nlm.nih.gov/gene?term=6%5BChr%5D%20AND%20%22Homo%20sapiens%22%5BOrganism%5D%20AND%20%28%22has%20ccds%22%5BProperties%5D%20AND%20alive%5Bprop%5D%29&cmd=DetailsSearch |date=2016-09-08 | accessdate=2017-05-28}}</ref>

| 2016-09-08

| 2017-03-29

|-

|style="text-align:center"| <ref name="UniProt">{{cite web | title=Human chromosome 6: entries, gene names and cross-references to MIM | website= UniProt | url=https://www.uniprot.org/docs/humchr06.txt |date=2018-02-28 | accessdate=2018-03-16}}</ref>

| 2018-02-28

|-

| [[National Center for Biotechnology Information|NCBI]] || 1,053 || 1,188 || 911

| 2017-05-19

|}

== Referensi ==

{{Reflist}}

 

[[Kategori:Biologi]]

 

{{biologi-stub}}