Pelatih Emma Hayes dari klub [[Chicago Red Stars]] mengundang Rapinoe untuk mengunjungi [[Chicago]] sebelum ia bergabung dengan klub tersebut pada [[2009]]. Rapinoe dipilih untuk bergabung dengan Chicago Red Stars yang bertanding dalam liga sepak bola wanita [[Women's Professional Soccer]] (WPS). Ini merupakan divisi sepak bola tertinggi untuk wanita pada saat itu. Rapinoe merupakan bagian dari tim inti untuk 17 dari 18 pertandingan. Selama 17 pertandingan tersebut, total waktu bermain Rapinoe di lapangan adalah 1.375 [[menit]].<ref name=":13">{{Cite web|url=https://bleacherreport.com/articles/184178-soccer-star-megan-rapinoe-chicago-style-standout|title=Soccer Star Megan Rapinoe: Chicago Style Standout|last=Howell|first=John|date=2009-05-26|website=Bleacher Report|language=en|access-date=2020-01-21}}</ref><ref>{{Cite web|url=http://www.redding.com/news/2009/jun/07/rapinoe-travels-from-north-state-soccer-to-red/|title=Rapinoe travels from north state soccer to Chicago Red Stars» Redding Record Searchlight|last=Jen|first=Jeffrey|date=2009-12-17|website=Redding|access-date=2020-01-21|archive-date=2009-12-17|archive-url=https://web.archive.org/web/20091217042859/http://www.redding.com/news/2009/jun/07/rapinoe-travels-from-north-state-soccer-to-red/|dead-url=unfit}}</ref><ref name=":16">{{Cite news|url=https://makassar.tribunnews.com/2019/07/10/tribunwiki-dapat-dua-penghargaan-di-piala-dunia-wanita-2019-ini-profil-megan-rapinoe|title=TRIBUNWIKI: Dapat Dua Penghargaan di Piala Dunia Wanita 2019, Ini Profil Megan Rapinoe|last=Aswan|first=Desi Triana|date=2019-07-10|work=[[Tribunnews|Tribunnews.com]]|language=id|access-date=2020-01-21}}</ref>
Rapinoe kemudian [[Pemain bebas transfer|berstatus bebas transfer]] pada saat Chicago Red Stars berhenti beroperasi pada [[Desember 2010]].<ref>{{Cite web|url=https://ourgamemagazine.wordpress.com/2010/12/13/chicago-red-stars-suspend-operation/|title=Chicago Red Stars suspend operations|last=|first=|date=2010-12-13|website=Our Game Magazine|language=en|access-date=2020-03-17}}</ref><ref name=":26" /> Pada bulan yang sama, Rapinoe menandatangani kontrak dengan [[Philadelphia Independence]].<ref name=":26">{{Cite web|url=http://gapersblock.com/tailgate/red-stars/|title=Red Stars - Gapers Block Tailgate {{!}} Chicago|last=Hettinger|first=Colin|date=2012-08-14|website=Gapers Block|access-date=2020-01-21}}</ref><ref>{{Cite web|url=http://www.phillysoccernews.com/teams/independence2.php?article_id=6223|title=MORE FIREPOWER Independence sign Rapinoe|last=|first=|date=2014-03-05|website=Philly Soccer News|access-date=2020-01-21|archive-date=2014-03-05|archive-url=https://web.archive.org/web/20140305235241/http://www.phillysoccernews.com/teams/independence2.php?article_id=6223|dead-url=unfit}}</ref><ref>{{Cite web|url=https://theathletic.com/1408980/2019/11/27/the-2010s-steps-forward-and-steps-back-each-year-in-womens-soccer/|title=The 2010s: Steps forward and back each year in women's...|last=Linehan|first=Meg|date=2019-11-27|website=The Athletic|access-date=2020-01-21}}</ref> Pada [[Juni 2011]], Rapinoe ditransfer ke klub [[MagicJack (WPS)|MagicJack]].<ref>{{Cite web|url=http://www.phillysoccernews.com/teams/independence2.php?article_id=6831|title=RAPINOE DEALT Independence send midfielder to magicJack|last=|first=|date=2013-11-03|website=Philly Soccer News|access-date=2020-01-21|archive-date=2013-11-03|archive-url=https://web.archive.org/web/20131103230123/http://www.phillysoccernews.com/teams/independence2.php?article_id=6831|dead-url=unfit}}</ref><ref>{{Cite web|url=http://womensprosoccer.net/philadelphia/news/general/112106-rapinoe-trade-mj|title=Women's Professional Soccer|last=|first=|date=2012-03-27|website=Womens Pro Soccer|access-date=2020-01-21|archive-date=2012-03-27|archive-url=https://web.archive.org/web/20120327152948/http://womensprosoccer.net/philadelphia/news/general/112106-rapinoe-trade-mj|dead-url=unfit}}</ref><ref>{{Cite web|url=https://equalizersoccer.com/2011/07/08/wps-top-of-table-clash-and-rapinoes-value/|title=WPS: Top of table clash and Rapinoe's value – Equalizer Soccer|last=Kassouf|first=Jeff|date=2011-07-08|website=Equalizer Soccer|language=en-US|access-date=2020-01-21}}</ref> Pada [[25 Oktober]] [[2011]], WPS membubarkan MagicJack. Rapinoe dan banyak pemain lainnya menjadi [[Pemain bebas transfer|agen bebas]].<ref>{{Cite web|url=https://equalizersoccer.com/2011/10/27/wps-terminates-magicjack-franchise/|title=WPS terminates magicJack franchise – Equalizer Soccer|last=Kassouf|first=Jeff|date=2011-10-27|website=Equalizer Soccer|language=en-US|access-date=2020-01-21}}</ref><ref>{{Cite web|url=https://www.washingtonexaminer.com/wps-terminates-magicjack-franchise-one-season-after-its-relocation-from-washington|title=WPS terminates magicJack franchise one season after its relocation from Washington|last=Stouffer|first=Craig|date=2011-10-27|website=Washington Examiner|language=en|access-date=2020-01-21}}</ref> Satu tahun kemudian, liga WPS pun dibubarkan. Keputusan untuk membubarkan liga ini sebagian besar dikarenakan masalah finansial. Sejarah menunjukkan bahwa mengoperasikan liga wanita yang sepenuhnya profesional di [[Amerika Serikat]] merupakan hal yang sulit.<ref>{{Cite news|title=US women's soccer league cancelled {{!}} Travis Clark|url=https://www.theguardian.com/sport/blog/2012/jan/31/uswnt-wps-2012-season-cancelled|newspaper=The Guardian|date=2012-01-31|access-date=2020-01-21|issn=0261-3077|language=en-GB|first=Travis|last=Clark}}</ref><ref>{{Cite news|title=After World Cup Thrills, Players Return to Unstable Women’s League|url=https://www.nytimes.com/2011/08/09/sports/soccer/unsteady-financial-footing-for-womens-soccer-league.html|newspaper=The New York Times|date=2011-08-08|access-date=2020-01-21|issn=0362-4331|language=en-US|first=JERÉ|last=LONGMAN}}</ref><ref>{{Cite web|url=https://edition.cnn.com/2012/01/31/sport/football/football-women-professional-soccer/index.html|title=U.S. women's pro soccer league suspended amid legal dispute|last=|first=|date=2012-01-31|website=CNN|access-date=2020-01-21}}</ref>
=== Sydney FC, Seattle Sounders Women, dan Olympique Lyonnais, 2011–2014 ===
