(3 revisi perantara oleh 2 pengguna tidak ditampilkan)
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<references group=""></references>{{Infobox medical condition|name=Psikosis induksi senyawa|image=|caption=|Synonyms=Gangguan psikotik induksi senyawa, psikosis induksi obat, psikosis toksik|DiseasesDB=|ICD10={{ICD10|F|10||f|10}}.5-{{ICD10|F|19||f|10}}.5|ICD9={{ICD9|292.1}}|OMIM=|MedlinePlus=|ICDO=|eMedicineSubj=|eMedicineTopic=|MeshID=D011605}} '''Psikosis induksi senyawa''' (umumnya dikenal sebagai '''psikosis toksik''') adalah bentuk [[Substance use disorder|gangguan penggunaan senyawa]] yang mana [[psikosis]] ini dapat dikaitkan dengan penggunaan senyawa. Psikosis ini dihasilkan oleh efek beracun bahan kimia atau obat-obatan, termasuk yang diproduksi oleh tubuh sendiri. Berbagai zat psikoaktif memiliki implikasi dalam menyebabkan atau memperburuk psikosis pengguna.
== Tanda dan gejala ==
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=== Lain ===
* Obat-obatan [[fluorokuinolon]] yang mana penggunaan fluorokuinolon dikaitkan dengan kasus serius psikosis toksik yang dilaporkan bersifat ireversibel dan permanen, lihat [[Adverse effects of fluoroquinolones|efek samping fluorokuinolon]] <ref name="pnawf">{{Cite journal|last=Cohen JS|date=December 2001|title=Peripheral Neuropathy Associated with Fluoroquinolones|url=http://fqvictims.org/fqvictims/News/neuropathy/Neuropathy.pdf|format=PDF|journal=Ann Pharmacother|volume=35|issue=12|pages=1540–7|doi=10.1345/aph.1Z429|pmid=11793615}}</ref><ref>{{Cite journal|year=2006|title=Gatifloxacin-induced hallucinations in a 19-year-old man|url=http://psy.psychiatryonline.org/cgi/content/full/47/4/360|dead-url=yes|journal=Psychosomatics|volume=47|issue=4|pages=360|doi=10.1176/appi.psy.47.4.360|pmid=16844899|archive-url=https://archive.istoday/20120722214034/http://psy.psychiatryonline.org/cgi/content/full/47/4/360|archive-date=2012-07-22}}</ref><ref>{{Cite journal|date=July 1995|title=Ciprofloxacin-induced acute psychosis|url=http://linkinghub.elsevier.com/retrieve/pii/S0090-4295(99)80171-X|journal=Urology|volume=46|issue=1|pages=102–3|doi=10.1016/S0090-4295(99)80171-X|pmid=7604468}}</ref><ref>{{Cite journal|last=Reeves RR|year=1992|title=Ciprofloxacin-induced psychosis|journal=Ann Pharmacother|volume=26|issue=7–8|pages=930–1|doi=10.1177/106002809202600716|pmid=1504404}}</ref><ref>{{Cite journal|date=March 1999|title=[Levofloxacin-induced neurological adverse effects such as convulsion, involuntary movement (tremor, myoclonus and chorea like), visual hallucination in two elderly patients]|url=|journal=Nippon Ronen Igakkai Zasshi|language=Japanese|volume=36|issue=3|pages=213–7|doi=10.3143/geriatrics.36.213|pmid=10388331}}</ref><ref>{{Cite journal|last=Reeves RR|year=1992|title=Ciprofloxacin-induced psychosis|journal=Ann Pharmacother|volume=26|issue=7–8|pages=930–1|doi=10.1177/106002809202600716|pmid=1504404}}</ref><ref>{{Cite journal|date=March 1999|title=[Levofloxacin-induced neurological adverse effects such as convulsion, involuntary movement (tremor, myoclonus and chorea like), visual hallucination in two elderly patients]|url=|journal=Nippon Ronen Igakkai Zasshi|language=Japanese|volume=36|issue=3|pages=213–7|doi=10.3143/geriatrics.36.213|pmid=10388331}}</ref><ref>{{Cite journal|date=April 2005|title=Ciprofloxacin-induced chorea|journal=Mov. Disord.|volume=20|issue=4|pages=513–4; author reply 514|doi=10.1002/mds.20425|pmid=15739219}}</ref><ref>{{Cite journal|date=April 2004|title=Mechanisms of pefloxacin-induced pain|url=|journal=Bull. Exp. Biol. Med.|volume=137|issue=4|pages=336–8|doi=10.1023/B:BEBM.0000035122.45148.93|pmid=15452594}}</ref><ref>{{Cite journal|date=May 2005|title=Generalized seizure and toxic epidermal necrolysis following levofloxacin exposure|url=http://www.theannals.com/cgi/pmidlookup?view=long&pmid=15827068|dead-url=yes|journal=Ann Pharmacother|volume=39|issue=5|pages=953–5|doi=10.1345/aph.1E587|pmid=15827068|archive-url=https://archive.istoday/20130111103748/http://www.theannals.com/cgi/pmidlookup?view=long&pmid=15827068|archive-date=2013-01-11}}</ref> Turunan kuinolin terkait, [[Mefloquine|meflokuin]] (Lariam) juga dikaitkan dengan psikosis.<ref>{{Cite journal|year=1993|title=[Encephalopathy and memory disorders during treatments with mefloquine]|url=|journal=Rev Med Interne|language=French|volume=14|issue=8|pages=788–91|doi=10.1016/S0248-8663(05)81426-2|pmid=8191092}}</ref><ref>{{Cite journal|date=June 1995|title=CNS adverse events associated with antimalarial agents. Fact or fiction?|url=|journal=Drug Saf|volume=12|issue=6|pages=370–83|doi=10.2165/00002018-199512060-00003|pmid=8527012}}</ref>
* Beberapa [[obat bebas]] termasuk:
** [[Dekstrometorfan]] (DXM) pada dosis tinggi.<ref name="DXM">{{Cite journal|last=Price|first=L. H.|last2=Lebel, J.|year=2000|title=Dextromethorphan-Induced Psychosis|url=http://ajp.psychiatryonline.org/cgi/content/full/157/2/304|journal=American Journal of Psychiatry|volume=157|issue=2|pages=304|doi=10.1176/appi.ajp.157.2.304|pmid=10671422}}</ref><ref>{{Cite journal|last=Lachover, L.|year=2007|title=Deciphering a Psychosis: A Case of Dextromethorphan-Induced Symptoms|url=http://www.primarypsychiatry.com/aspx/articledetail.aspx?articleid=953|journal=Primary Psychiatry|volume=14|issue=1|pages=70–72|access-date=2019-02-05|archive-date=2013-03-30|archive-url=https://web.archive.org/web/20130330163952/http://www.primarypsychiatry.com/aspx/articledetail.aspx?articleid=953|dead-url=yes}}</ref>
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** [[Ketamin]]
* [[Bahan kimia penelitian]] sintetik sebagai rekreasi termasuk:
** [[JWH-018]] dan beberapa [[Synthetic cannabinoids|kanabinoid sintetis]] lain, atau campuran yang mengandung mereka ( misalnya "Spice", "Kronic", "MNG" atau "Mr. Nice Guy", "Relaxinol", dll. ).<ref><div> http://www.airforcetimes.com/news/2011/06/air-force-spice-users-risk-psychosis-says-doctor-061111w/ risiko psikosis pengguna bumbu, kata dokter oleh Gidget Fuentes - staf penulis yang mengakses 06- 25-2011 </div></ref> Berbagai senyawa "JWH-XXX..." dalam "Spice" atau "Incense" juga ditemukan dan didapati menyebabkan psikosis pada beberapa orang.<ref>{{Cite journal|last=Shalit|first=Nadav|last2=Barzilay|first2=Ran|last3=Shoval|first3=Gal|last4=Shlosberg|first4=Dan|last5=Mor|first5=Nofar|last6=Zweigenhaft|first6=Nofar|last7=Weizman|first7=Abraham|last8=Krivoy|first8=Amir|date=2016-07-05|title=Characteristics of Synthetic Cannabinoid and Cannabis Users Admitted to a Psychiatric Hospital: A Comparative Study|url=http://www.psychiatrist.com/jcp/article/Pages/2016/aheadofprint/15m09938.aspx|journal=The Journal of Clinical Psychiatry|language=English|volume=77|issue=|pages=e989|doi=10.4088/JCP.15m09938|issn=0160-6689|pmid=27379411}}</ref><ref>{{Cite journal|last=Every-Palmer S|year=2010|title=Warning: legal synthetic cannabinoid-receptor agonists such as JWH-018 may precipitate psychosis in vulnerable individuals|url=|journal=Addiction|volume=105|issue=10|pages=1859–60|doi=10.1111/j.1360-0443.2010.03119.x|pmid=20840203}}</ref><ref>{{Cite journal|year=2010|title=The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes|url=|journal=Schizophr. Res.|volume=118|issue=1–3|pages=309–10|doi=10.1016/j.schres.2009.12.001|pmid=20056392}}</ref>
** [[Mephedrone|Mefedron]] dan obat sejenis amfetamin terkait yang dijual sebagai "garam mandi" atau "makanan tumbuhan".<ref><div> https://www.addictions.com/bath-salts/ Kecanduan Garam Mandi, Diakses 06-25-2011 </div></ref>