Guaifenesin: Perbedaan antara revisi

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WanaraLima (bicara | kontrib)
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Muhammad Anas Sidik (bicara | kontrib)
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(4 revisi perantara oleh 4 pengguna tidak ditampilkan)
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<!-- Pharmacokinetic data -->|bioavailability=|protein_bound=|metabolism=[[Kidney]]|elimination_half-life=1–5 hours<ref name="pmid8218524">{{cite journal | vauthors= Aluri JB, Stavchansky S | title= Determination of guaifenesin in human plasma by liquid chromatography in the presence of pseudoephedrine | journal= J Pharm Biomed Anal | year= 1993 | volume= 11 | issue= 9 | pages= 803–8 | pmid= 8218524 | doi= 10.1016/0731-7085(93)80072-9 | pmc= | url= https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8218524 | access-date= 2022-03-14 | archive-date= 2021-08-28 | archive-url= https://web.archive.org/web/20210828094822/https://www.sciencedirect.com/science/article/abs/pii/0731708593800729?via%3Dihub | url-status= live }}</ref>|excretion=<!-- Chemical and physical data -->|C=10|H=14|O=4|smiles=O(c1ccccc1OC)CC(O)CO|StdInChI=1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3|StdInChI_Ref={{stdinchicite|correct|chemspider}}|StdInChIKey=HSRJKNPTNIJEKV-UHFFFAOYSA-N|StdInChIKey_Ref={{stdinchicite|correct|chemspider}}}}
 
'''Guaifenesin''' atau '''gliseril guaiakolat''' (disingkat '''GG''') adalah [[Medikasi|obat]] yang digunakan untuk mengatasi gejala [[Ingus|batuk berdahak]] [[Dahak|dari]] [[Saluran napas|saluran pernafasan]] . <ref name="AHFS2019">{{Cite web|title=Guaifenesin Monograph for Professionals|url=https://www.drugs.com/monograph/guaifenesin.html|website=Drugs.com|publisher=American Society of Health-System Pharmacists|language=en|archive-url=https://web.archive.org/web/20190415013952/https://www.drugs.com/monograph/guaifenesin.html|archive-date=15 April 2019|access-date=25 March 2019|url-status=live}}</ref> Belum diketahui secara jelas apakah guaifenesin bisa mengurangi gejala batuk. <ref name="AHFS2019">{{cite web |title=Guaifenesin Monograph for Professionals |url=https://www.drugs.com/monograph/guaifenesin.html |website=Drugs.com |publisher=American Society of Health-System Pharmacists |accessdate=25 March 2019 |language=en |archive-date=15 April 2019 |archive-url=https://web.archive.org/web/20190415013952/https://www.drugs.com/monograph/guaifenesin.html |url-status=live }}</ref> Penggunaan obat guaifenesin tidak direkomendasikan untuk anak dibawah usia 6 tahun. <ref name="BNF76">{{Cite book|date=2018|title=British national formulary : BNF 76|publisher=Pharmaceutical Press|isbn=9780857113382|edition=76|pages=295}}</ref> Penggunaan guaifenesin sering dikombinasikan dengan obat lain. <ref name="AHFS2019">{{cite web |title=Guaifenesin Monograph for Professionals |url=https://www.drugs.com/monograph/guaifenesin.html |website=Drugs.com |publisher=American Society of Health-System Pharmacists |accessdate=25 March 2019 |language=en |archive-date=15 April 2019 |archive-url=https://web.archive.org/web/20190415013952/https://www.drugs.com/monograph/guaifenesin.html |url-status=live }}</ref> Rute pemberian obat ini melalui oral. <ref name="AHFS2019">{{cite web |title=Guaifenesin Monograph for Professionals |url=https://www.drugs.com/monograph/guaifenesin.html |website=Drugs.com |publisher=American Society of Health-System Pharmacists |accessdate=25 March 2019 |language=en |archive-date=15 April 2019 |archive-url=https://web.archive.org/web/20190415013952/https://www.drugs.com/monograph/guaifenesin.html |url-status=live }}</ref>
 
Efek samping obat yang umum terjadi pada penggunaan obat ini seperti [[pusing]], kantuk, ruam kulit, dan mual. <ref name="PPA2019">{{Cite web|title=Guaifenesin|url=https://www.drugs.com/ppa/guaifenesin-glyceryl-guaiacolate.html|publisher=Drugs.com|archive-url=https://web.archive.org/web/20171229052430/https://www.drugs.com/ppa/guaifenesin-glyceryl-guaiacolate.html|archive-date=2017-12-29|access-date=2019-03-25|url-status=live}}</ref> Penggunaan obat ini untuk ibu hamil obat ini sepertinya aman, walaupun belum diteliti secara lanjut. <ref name="Wei2013">{{Cite book|last=Weiner|first=Carl P.|last2=Rope|first2=Kate|date=2013|url=https://archive.org/details/completeguidetom0000wein_t9k5|title=The Complete Guide to Medications During Pregnancy and Breastfeeding: Everything You Need to Know to Make the Best Choices for You and Your Baby|publisher=St. Martin's Press|isbn=9781250037206|page=PT282|language=en|url-access=registration}}</ref> Mekanisme kerja guaifenesin diyakini bekerja dengan membuat sekresi saluran napas lebih cair. <ref name="AHFS2019">{{Cite web|title=Guaifenesin Monograph for Professionals|url=https://www.drugs.com/monograph/guaifenesin.html|website=Drugs.com|publisher=American Society of Health-System Pharmacists|language=en|archive-url=https://web.archive.org/web/20190415013952/https://www.drugs.com/monograph/guaifenesin.html|archive-date=15 April 2019|access-date=25 March 2019|url-status=live}}</ref>
 
== Referensi ==
[[Kategori:Ekspektoran]]
 
[[Kategori:Obat dengan cara kerja yang belum diketahui]]
[[Kategori:FarmasiEter katekol]]
[[Kategori:Eter gliserol]]
[[Kategori:Senyawa metoksi]]
<references />{{Farmasi-stub}}