Metformin: Perbedaan antara revisi

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Muhammad Anas Sidik (bicara | kontrib)
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k Removing from Category:Antidiabetes using Cat-a-lot
 
(4 revisi perantara oleh 2 pengguna tidak ditampilkan)
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<!-- Clinical data -->
| pronounce = {{IPAc-en|m|ɛ|t|ˈ|f|ɔːr|m|ᵻ|n}}, {{respell|met|FOR|min}}
| tradename = Diabit, Forbetes, Glikos, Glucophage, [[#Formulations|others]]Gludepatic, dll
| Drugs.com = {{drugs.com|monograph|metformin-hydrochloride}}
| MedlinePlus = a696005
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| pregnancy_AU_comment = <ref name="Drugs.com pregnancy">{{cite web | title=Metformin Use During Pregnancy | website=Drugs.com | date=10 September 2019 | url=https://www.drugs.com/pregnancy/metformin.html | access-date=4 February 2020 | archive-date=16 April 2020 | archive-url=https://web.archive.org/web/20200416182342/https://www.drugs.com/pregnancy/metformin.html | url-status=live }}</ref>
| pregnancy_category =
| routes_of_administration = [[Oral administration|By mouth]]
| class = [[Antidiabetic agent]]
| ATC_prefix = A10
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| bioavailability = 50–60%<ref name = D95>{{cite journal | vauthors = Dunn CJ, Peters DH | title = Metformin. A review of its pharmacological properties and therapeutic use in non-insulin-dependent diabetes mellitus | journal = Drugs | volume = 49 | issue = 5 | pages = 721–49 | date = May 1995 | pmid = 7601013 | doi = 10.2165/00003495-199549050-00007 }}</ref><ref name=D03>{{cite journal | vauthors = Hundal RS, Inzucchi SE | title = Metformin: new understandings, new uses | journal = Drugs | volume = 63 | issue = 18 | pages = 1879–94 | year = 2003 | pmid = 12930161 | doi = 10.2165/00003495-200363180-00001 }}</ref>
| protein_bound = Minimal<ref name = D95 />
| metabolism = NotBukan bydengan liverhati<ref name = D95 />
| metabolites =
| onset =
| elimination_half-life = 4–8.,7 hoursjam<ref name = D95 />
| duration_of_action =
| excretion = UrineUrin (90%)<ref name = D95 />
 
<!-- Identifiers -->
Baris 96:
| NIAID_ChemDB =
| PDB_ligand =
| synonyms = ''N'',''N''-dimethylbiguanidedimetilbiguanida<ref>{{cite journal | vauthors = Sirtori CR, Franceschini G, Galli-Kienle M, Cighetti G, Galli G, Bondioli A, Conti F | title = Disposition of metformin (N,N-dimethylbiguanide) in man | journal = Clinical Pharmacology and Therapeutics | volume = 24 | issue = 6 | pages = 683–93 | date = December 1978 | pmid = 710026 | doi = 10.1002/cpt1978246683 | s2cid = 24531910 }}</ref>
 
<!-- Chemical and physical data -->
| IUPAC_name = ''N'',''N''-DimethylimidodicarbonimidicDimetilimidodikarbonimidat diamidediamida
| C = 4 | H = 11 | N = 5
| SMILES = CN(C)C(=N)N=C(N)N
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== Referensi==
{{reflist}}{{Farmasi-stub}}
[[Kategori:Antidiabetes]]
[[Kategori:Obat Esensial Nasional Indonesia]]
[[Kategori:Biguanid]]
[[Kategori:guanidina]]
[[Kategori:ObatAntipenuaan]]
[[Kategori:Obat dengan cara kerja yang belum diketahui]]
[[Kategori:AntidiabetesObat piatu]]
[[Kategori:Obat yang dikembangkan oleh Boehringer Ingelheim]]
[[Kategori:Obat yang dikembangkan oleh Merck KGaA]]
[[Kategori:Obat Esensial Organisasi Kesehatan Dunia]]