Konten dihapus Konten ditambahkan
|
|
(3 revisi perantara oleh 2 pengguna tidak ditampilkan) |
'''LY-2940094''' adalah antagonis selektif dan poten untuk reseptor nociceptin yang sedang dikembangkan oleh [[Eli Lilly and Company|Eli Lilly]] untuk terapi depresi mayor dan ketergantungan alkohol.<ref name="DaleBang-Andersen2015">{{cite journal|last1 = Dale|first1 = Elena|last2 = Bang-Andersen|first2 = Benny|last3 = Sánchez|first3 = Connie|title = Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs|journal = Biochemical Pharmacology|volume = 95|issue = 2|year = 2015|pages = 81–97|issn = 00062952|doi = 10.1016/j.bcp.2015.03.011|url = http://ac.els-cdn.com/S0006295215001562/1-s2.0-S0006295215001562-main.pdf?_tid=f417c406-fa7f-11e4-8069-00000aacb35e&acdnat=1431638999_2432ab0a8c2b11b51e25962a430aee96}}</ref><ref name="Yin2015">{{cite journal|last1 = Yin|first1 = Xin|last2 = Guven|first2 = Nuri|last3 = Dietis|first3 = Nikolas|title = Opioids in Depression: Not Quite There Yet|journal = UK Journal of Pharmaceutical and Biosciences|volume = 3|issue = 1|year = 2015|pages = 12–17|issn = |doi = |url = http://www.researchgate.net/profile/Nikolas_Dietis/publication/273694299_Opioids_in_Depression_Not_Quite_There_Yet/links/5508c91a0cf27e990e0ce086.pdf}}</ref> Sampai dengan 2014, LY-2940094 sedang menjalani uji klinik fase II untuk kedua indikasi tersebut.<ref name="DaleBang-Andersen2015">{{cite journal|last1 = Dale|first1 = Elena|last2 = Bang-Andersen|first2 = Benny|last3 = Sánchez|first3 = Connie|title = Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs|journal = Biochemical Pharmacology|volume = 95|issue = 2|year = 2015|pages = 81–97|issn = 00062952|doi = 10.1016/j.bcp.2015.03.011|url = http://ac.els-cdn.com/S0006295215001562/1-s2.0-S0006295215001562-main.pdf?_tid=f417c406-fa7f-11e4-8069-00000aacb35e&acdnat=1431638999_2432ab0a8c2b11b51e25962a430aee96}}</ref><ref name="Yin2015">{{cite journal|last1 = Yin|first1 = Xin|last2 = Guven|first2 = Nuri|last3 = Dietis|first3 = Nikolas|title = Opioids in Depression: Not Quite There Yet|journal = UK Journal of Pharmaceutical and Biosciences|volume = 3|issue = 1|year = 2015|pages = 12–17|issn = |doi = |url = http://www.researchgate.net/profile/Nikolas_Dietis/publication/273694299_Opioids_in_Depression_Not_Quite_There_Yet/links/5508c91a0cf27e990e0ce086.pdf}}</ref> Sampai saat ini struktur kimia senyawa ini masih belum dipublikasikan.<ref name="DaleBang-Andersen2015">{{cite journal|last1 = Dale|first1 = Elena|last2 = Bang-Andersen|first2 = Benny|last3 = Sánchez|first3 = Connie|title = Emerging mechanisms and treatments for depression beyond SSRIs and SNRIs|journal = Biochemical Pharmacology|volume = 95|issue = 2|year = 2015|pages = 81–97|issn = 00062952|doi = 10.1016/j.bcp.2015.03.011|url = http://ac.els-cdn.com/S0006295215001562/1-s2.0-S0006295215001562-main.pdf?_tid=f417c406-fa7f-11e4-8069-00000aacb35e&acdnat=1431638999_2432ab0a8c2b11b51e25962a430aee96}}</ref>
== ReferencesReferensi ==
{{Reflist|2}}
[[Kategori:ObatOpioid sintetik]]
[[Kategori:Antidepresan]]
[[Kategori:Antagonis reseptor nosiseptin]]
|