Anemia sel sabit: Perbedaan antara revisi
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Baris 6:
| field = [[Hematologi]], [[genetika kedokteran]]
| synonyms = Penyakit sel sabit; drepanositosis (tertanggal)
| symptoms = Serangan nyeri, [[anemia]], pembengkakan di tangan dan kaki, infeksi bakteri, [[strok]]<ref name=NIH2015Sign>{{cite web|title=What Are the Signs and Symptoms of Sickle Cell Disease?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/signs|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160309034557/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/signs|archive-date=9 March 2016}}</ref>
| complications = [[Sakit kronis]], strok, nekrosis tulang aseptik, [[batu empedu]], ulkus kaki, [[priapisme]], [[hipertensi paru]], masalah penglihatan, masalah ginjal.<ref name=NIH2015What>{{cite web|title=What Is Sickle Cell Disease?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160306021706/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/|archive-date=6 March 2016}}</ref>
| onset = Usia 5–6 bulan<ref name=NIH2015Sign/>
| duration =
| causes = Genetik, Mutasi homozigot pada gen hemoglobin S.<ref name=NIH2015Caus>{{cite web|title=What Causes Sickle Cell Disease?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/causes|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160324034054/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/causes|archive-date=24 March 2016}}</ref>
| risks =
| diagnosis = [[uji darah]]<ref name=NIH2015Diag>{{cite web|title=How Is Sickle Cell Disease Diagnosed?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/diagnosis|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160309032258/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/diagnosis|archive-date=9 March 2016}}</ref>
| differential =
| prevention =
| treatment = [[Vaksinasi]], [[antibiotik]], asupan cairan tinggi, suplementasi [[asam folat]], obat [[analgesik|pereda nyeri]], [[transfusi darah]]<ref name=WHO2011>{{cite web|title=Sickle-cell disease and other haemoglobin disorders Fact sheet N°308|url=https://www.who.int/mediacentre/factsheets/fs308/en/|access-date=8 March 2016|date=January 2011|url-status=dead|archive-url=https://web.archive.org/web/20160309034307/http://www.who.int/mediacentre/factsheets/fs308/en/|archive-date=9 March 2016}}</ref><ref name=NIH2015Tx>{{cite web|title=How Is Sickle Cell Disease Treated?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/treatment|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160309042159/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/treatment|archive-date=9 March 2016}}</ref>
| medication =
| prognosis = [[Harapan hidup]] 40–60 tahun (negara maju)<ref name=NIH2015What/>
| frequency = 4,4 juta (2015)<ref name=GBD2015Pre>{{cite journal | vauthors = Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, Carter A, etal | collaboration = GBD 2015 Disease and Injury Incidence and Prevalence Collaborators | title = Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 | journal = Lancet | volume = 388 | issue = 10053 | pages = 1545–1602 | date = October 2016 | pmid = 27733282 | pmc = 5055577 | doi = 10.1016/S0140-6736(16)31678-6 }}</ref>
| deaths = 114,800 (2015)<ref name=GBD2015De>{{cite journal | vauthors = Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, etal | collaboration = GBD 2015 Mortality and Causes of Death Collaborators | title = Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015 | journal = Lancet | volume = 388 | issue = 10053 | pages = 1459–1544 | date = October 2016 | pmid = 27733281 | pmc = 5388903 | doi = 10.1016/S0140-6736(16)31012-1 }}</ref>
}}
'''Anemia sel sabit''' atau '''penyakit sel sabit''' adalah kondisi serius di mana sel-[[sel darah merah]] menjadi berbentuk [[bulan sabit]], seperti huruf [[C]]. Sel darah merah normal berbentuk donat tanpa lubang (lingkaran, pipih di bagian tengahnya), sehingga memungkinkan mereka melewati [[pembuluh darah]] dengan mudah dan memasok [[oksigen]] bagi seluruh bagian tubuh. Sulit bagi sel darah merah berbentuk bulan sabit untuk melewati pembuluh darah terutama di bagian [[pembuluh darah]] yang jadi menyempit dengan sendirinya, karena sel darah merah ini akan tersangkut dan akan menimbulkan rasa [[nyeri]], [[infeksi]] serius, dan kerusakan organ pada tubuh.
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