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'''Kromosom Philadelphia''' ditemukanatau '''''Philadelphia padatranslocation''''' tahun('''Ph''') 1959adalah olehkelainan Davidgenetik A. Hungerford dan Peter C. Nowell ketika mendeteksi kelainan kecilspesifik pada [[kromosom dari22]] sel darahkanker yang[[leukimia bersumber dari dua pasien leukemia mielogenusmieloid kronis]] (CML).<ref>{{Cite web|date=2017-05-08|title=The Philadelphia Chromosome:History- andan Implications for the Futureoverview {{!}} FoxScienceDirect ChaseTopics|url=https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/philadelphia-chromosome|website=www.sciencedirect.com|access-date=2024-12-17}}</ref><ref>{{Cite Cancerweb|title=How Center -the Philadelphia PAchromosome forms|url=https://www-foxchase-org.translatemayoclinic.googorg/aboutdiseases-usconditions/history/discoverieschronic-foxmyelogenous-chase-researchleukemia/multimedia/how-the-philadelphia-chromosome-forms/philadelphiaimg-chromosome20007421?_x_tr_sl=en&_x_tr_tl=id&_x_tr_hl=id&_x_tr_pto=tc|website=www.foxchase.orgMayo Clinic|language=en|access-date=2024-12-1617}}</ref> Kromosom Philadelphiaini terbentukpertama padakali saatdiidentifikasi sebagai kromosom 9yang danberukuran kromosomsangat 22kecil putuspada lalusel bertukarCML bagianpada sehingga1959 membentukoleh [[David Hungerford]] dan [[Peter Nowell]] ketika mendeteksi kelainan kecil pada kromosom 22dari sel darah yang pendekbersumber dari dua pasien CML di Pusat Kanker Fox Chase, [[Philadelphia, Pennsylvania|Philadelphia]].<ref name=":1">{{Cite web|date=2017-05-08|title=HowThe Philadelphia Chromosome: History and Implications for the PhiladelphiaFuture chromosome{{!}} formsFox Chase Cancer Center - Philadelphia PA|url=https://www-mayoclinic-org.translatefoxchase.googorg/diseasesabout-conditionsus/chronic-myelogenous-leukemiahistory/multimedia/howdiscoveries-thefox-chase-research/philadelphia-chromosome-forms/imgphiladelphia-20007421?_x_tr_sl=en&_x_tr_tl=id&_x_tr_hl=id&_x_tr_pto=tcchromosome|website=Mayo Clinicwww.foxchase.org|language=en|access-date=2024-12-16}}</ref>
