Deferoksamin: Perbedaan antara revisi
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Baris 1:
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{{Infobox drug
| drug_name =
| INN =
| type =<!-- empty -->
| IUPAC_name = ''N'''-{5-[Acetyl(hydroxy)amino]pentyl}-''N''-[5-({4-[(5-aminopentyl)(hydroxy)amino]-4-oxobutanoyl}amino)pentyl]-''N''-hydroxysuccinamide
| image = Deferoxamine-2D-skeletal.png
| width =
| alt =
| image2 = Deferoxamine-3D-vdW.png
| width2 =
| alt2 =
| imageL =
| widthL =
| altL =
| imageR =
| widthR =
| altR =
| caption = Rumus kerangka dan model ruang isi deferoksamin
<!-- Clinical data -->
| pronounce =
| tradename = Desferal
| Drugs.com = {{drugs.com|monograph|deferoxamine-mesylate}}
| MedlinePlus =
| licence_EU = <!-- EMA requires brand name -->
| licence_US = <!-- FDA may use generic name -->
| DailyMedID = <!-- preference to licence_US -->
| pregnancy_AU = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_AU_comment =
| pregnancy_US = C
| pregnancy_US_comment =
| pregnancy_category=
| dependency_liability =
| addiction_liability =
| routes_of_administration = {{unbulleted list|intramuskular|intravena|subkutan}}
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA_comment =
| legal_DE = <!-- Anlage I, II, III or Unscheduled-->
| legal_DE_comment =
| legal_NZ = <!-- Class A, B, C -->
| legal_NZ_comment =
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_UK_comment =
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_US_comment =
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV-->
| legal_UN_comment =
| legal_status = <!--For countries not listed above-->
<!-- Pharmacokinetic data -->
| bioavailability =
| protein_bound =
| metabolism =
| metabolites =
| onset =
| elimination_half-life = 6 jam
| duration_of_action =
| excretion =
<!-- Identifiers -->
| CAS_number = 70-51-9
| CAS_supplemental = {{cascite|correct|CAS}}
| ATCvet =
| ATC_prefix = V03
| ATC_suffix = AC01
| ATC_supplemental =
| PubChem = 2973
| PubChemSubstance =
| IUPHAR_ligand =
| DrugBank = DB00746
| ChemSpiderID = 2867
| UNII = J06Y7MXW4D
| KEGG = D03670
| ChEBI = 4356
| ChEMBL = 556
| NIAID_ChemDB =
| synonyms = desferrioxamine B, desferoxamine B, DFO-B, DFB ,N'-[5-(Acetyl-hydroxy-amino)pentyl]-N-[5-[3-(5-aminopentyl-hydroxy-carbamoyl) propanoylamino]pentyl]-N-hydroxy-butane diamide
<!-- Chemical data -->
| chemical_formula =
| C=25 | H=48 | Ag= | Al= | As= | Au= | B= | Bi= | Br= | Ca= | Cl= | Co= | F= | Fe= | Gd= | I=
| K= | Li= | Mg= | Mn= | N=6 | Na= | O=8 | P= | Pt= | S= | Sb= | Se= | Sr= | Tc= | Zn= | charge=
| molecular_weight =
| SMILES = CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
| Jmol =
| StdInChI = 1S/C25H48N6O8/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34)
| StdInChI_comment = {{stdinchicite|correct|chemspider}}
| StdInChIKey = UBQYURCVBFRUQT-UHFFFAOYSA-N
| density =
| density_notes =
| melting_point =
| melting_high =
| melting_notes =
| boiling_point =
| boiling_notes =
| solubility =
| specific_rotation =
}}
'''Deferoksamin''' adalah obat yang mengikat besi dan [[aluminium]]. Ini secara khusus digunakan dalam overdosis besi, hemochromatosis baik karena [[transfusi darah]] multipel atau kondisi genetik yang mendasarinya, dan toksisitas aluminium pada orang yang menggunakan [[dialisis]].
{{Authority control}}
[[Kategori:Asam hidroksamat]]
[[Kategori:Obat Esensial Nasional Indonesia]]
[[Kategori:Amina]]
[[Kategori:Antidot]]
[[Kategori:Karboksamida]]
[[Kategori:Obat Esensial Organisasi Kesehatan Dunia]]
[[Kategori:Siderofor]]
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