Fomepizol: Perbedaan antara revisi
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{{Infobox drug
| type = <!-- empty -->
| image = Fomepizole.svg
| width = 125px
| alt = Rumus struktur fomepizol
| image2 = Fomepizole 3D ball.png
| width2 = 125px
| alt2 = Model bola dan batang molekul fomepizol
| caption = Struktur kimia fomepizol
<!-- Clinical data -->
| pronounce = {{IPAc-en|ˌ|f|oʊ|ˈ|m|ɛ|p|ɪ|z|oʊ|l|}}
| tradename = Antizol, dan lainnya
| Drugs.com = {{Drugs.com|monograph|fomepizole}}
| MedlinePlus =
| licence_EU = <!-- EMA requires brand name -->
| licence_US = <!-- FDA may use generic name -->
| DailyMedID = Fomepizole
| pregnancy_AU = <!-- A/B1/B2/B3/C/D/X -->
| pregnancy_AU_comment =
| pregnancy_US = C
| pregnancy_US_comment =
| pregnancy_category=
| dependency_liability =
| addiction_liability =
| routes_of_administration = [[Intravena]]
| ATCvet =
| ATC_prefix = V03
| ATC_suffix = AB34
| ATC_supplemental =
<!-- Legal status -->
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled -->
| legal_AU_comment =
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_CA_comment =
| legal_DE = <!-- Anlage I, II, III or Unscheduled -->
| legal_DE_comment =
| legal_NZ = <!-- Class A, B, C -->
| legal_NZ_comment =
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C -->
| legal_UK_comment =
| legal_US = Rx-only
| legal_US_comment = <ref>{{cite web | title=Antizol- fomepizole injection | website=DailyMed | url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c045b5a8-b220-4f0a-a831-155b29c19454 | access-date=24 December 2020 | archive-date=2022-06-26 | archive-url=https://web.archive.org/web/20220626213628/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c045b5a8-b220-4f0a-a831-155b29c19454 | dead-url=no }}</ref>
| legal_EU =
| legal_EU_comment =
| legal_UN = <!-- N I, II, III, IV / P I, II, III, IV -->
| legal_UN_comment =
| legal_status = <!-- For countries not listed above -->
<!-- Pharmacokinetic data -->
| bioavailability =
| protein_bound =
| metabolism =
| metabolites =
| onset =
| elimination_half-life =
| duration_of_action =
| excretion =
<!-- Identifiers -->
| CAS_number = 7554-65-6
| CAS_supplemental = {{cascite|correct|CAS}}
| PubChem = 3406
| IUPHAR_ligand =
| DrugBank = DB01213
| ChemSpiderID = 3289
| UNII = 83LCM6L2BY
| KEGG = D00707
| ChEBI = 5141
| ChEMBL = 1308
| NIAID_ChemDB =
| synonyms = 4-Metilpirazol
<!-- Chemical data -->
| IUPAC_name = 4-Metil-1''H''-pirazol
| C=4 | H=6 | N=2
| SMILES = CC1=CNN=C1
| StdInChI = 1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6)
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RIKMMFOAQPJVMX-UHFFFAOYSA-N
| density = 0,99
| density_notes =
| melting_point =
| melting_high =
| melting_notes =
| boiling_point = 207
| boiling_notes = (pada 97,3 kPa)
| solubility =
| specific_rotation =
}}
'''Fomepizol''' atau '''4-metilpirazol''' adalah obat yang digunakan untuk mengobati keracunan metanol dan [[Keracunan etilena glikol|etilena glikol]].<ref name="AHFS2016" /> Fomepizol dapat digunakan secara tunggal atau kombinasi dengan [[hemodialisis]].<ref name="AHFS2016" /> Obat ini diberikan melalui injeksi intravena.<ref name="AHFS2016">{{Cite web|title=Fomepizole|url=https://www.drugs.com/monograph/fomepizole.html|website=Drugs.com|publisher=The American Society of Health-System Pharmacists|archive-url=https://web.archive.org/web/20161221003710/https://www.drugs.com/monograph/fomepizole.html|archive-date=21 Desember 2016|access-date=21 Oktober 2022|url-status=live}}</ref>
Efek samping yang umum terjadi antara lain sakit kepala, mual, dan rasa kantuk.<ref name="AHFS2016" /> Keamanan penggunaan fomepizol selama [[kehamilan]] masih belum diketahui secara pasti.<ref name="AHFS2016" /> Mekanisme aksi fomepizol yakni
Fomepizol telah digunakan di Amerika Serikat sejak tahun 1997.<ref name="AHFS2016" /> Fomepizol termasuk dalam [[Daftar Obat Esensial Organisasi Kesehatan Dunia]].<ref name="WHO21st">{{Cite book|vauthors=((World Health Organization))|year=2019|title=World Health Organization model list of essential medicines: 21st list 2019|location=Jenewa|publisher=World Health Organization|hdl=10665/325771|id=WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO|author-link=World Health Organization|url-status=live|hdl-access=free}}</ref>
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== Referensi ==
{{reflist}}
[[Kategori:Obat Esensial Organisasi Kesehatan Dunia]]
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