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'''TrazodoneTrazodon''' adalah obat golongan [[antidepresan]] . <ref name="AHFS2018">{{Cite web|title=Trazodone Hydrochloride|url=https://www.drugs.com/monograph/trazodone-hydrochloride.html|publisher=The American Society of Health-System Pharmacists|archive-url=https://web.archive.org/web/20180919174109/https://www.drugs.com/monograph/trazodone-hydrochloride.html|archive-date=19 September 2018|access-date=8 January 2018|url-status=live}}</ref> Obat ini bisa digunakan untuk mengatasi [[gangguan depresi mayor]], [[gangguan kecemasan]], [[insomnia]] dan, juga bisa dikombinasikan dengan obat lain untuk mengatasi, ketergantungan alkohol . <ref name="AHFS2018" /> <ref name="CFPC2021">{{Cite web|last=Ton|first=Joey|date=15 November 2021|title=#302 Still awake? Trazodone for insomnia|url=https://cfpclearn.ca/tfp302/|website=CFPCLearn|archive-url=https://web.archive.org/web/20230328114109/https://cfpclearn.ca/tfp302/|archive-date=28 March 2023|access-date=14 June 2023|url-status=live}}</ref> Trazodone bisa dikonsumsi secara oral. <ref name="AHFS2018" />
Kejadian efek samping yang kerap terjadi yakni [[Xerostomia|mulut kering]], rasa ingin pingsan, muntah, dan rasa sakit kepala. <ref name="AHFS2018" /> Efek samping yang parah muncul rasa ingin [[bunuh diri]], [[mania]], [[Aritmia]], dan [[Priapisme]] . <ref name="AHFS2018" /> Belum diketahui obat ini aman untuk masa [[kehamilan]], dan masa [[menyusui]] . <ref>{{Cite web|title=Trazodone Use During Pregnancy|url=https://www.drugs.com/pregnancy/trazodone.html|website=Drugs.com|archive-url=https://web.archive.org/web/20190810191222/https://www.drugs.com/pregnancy/trazodone.html|archive-date=10 August 2019|access-date=7 January 2018|url-status=live}}</ref> Trazodone merupakan senyawa fenilpiperazin dari kelas antagonis serotonin dan penghambat reuptake (SARI). <ref>{{Cite book|last=Stahl|first=Stephen M.|date=2008|url=https://books.google.ca/books?id=cWbYxSfKN3cC&pg=PA567|title=Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications|publisher=Cambridge University Press|isbn=9780521857024|page=567|language=en|access-date=6 August 2020|archive-url=https://web.archive.org/web/20190811032910/https://books.google.ca/books?id=cWbYxSfKN3cC&pg=PA567|archive-date=11 August 2019|url-status=live}}</ref> <ref>{{Cite book|last=Lemke|first=Thomas L.|last2=Williams|first2=David A.|date=2008|url=https://books.google.ca/books?id=R0W1ErpsQpkC&pg=PA586|title=Foye's Principles of Medicinal Chemistry|publisher=Lippincott Williams & Wilkins|isbn=9780781768795|page=586|language=en|access-date=6 August 2020|archive-url=https://web.archive.org/web/20190812031919/https://books.google.ca/books?id=R0W1ErpsQpkC&pg=PA586|archive-date=12 August 2019|url-status=live}}</ref> Obat trazodone juga memiliki efek lain yakni rasa menenangkan. <ref name="BNF69">{{Cite book|date=2015|title=British national formulary: BNF 69|url=https://archive.org/details/bnf69britishnati0000unse|publisher=British Medical Association|isbn=9780857111562|edition=69th|pages=[https://archive.org/details/bnf69britishnati0000unse/page/257 257]–258}}</ref>
== Referensi ==
[[Kategori:ObatAntidepresan]]
[[Kategori:FarmasiObat hewan]]
[[Kategori:Triazolopiridina]]
[[Kategori:Urea]]
[[Kategori:Penghambat pengambilan kembali serotonin]]
[[Kategori:Antagonis reseptor H1]]
[[Kategori:Anksiolitik]]
[[Kategori:Hipnotik]]
[[Kategori:Penghalang alfa-1]]
[[Kategori:Agonis 5-HT1A]]
[[Kategori:Antagonis 5-HT2A]]
<references />{{Farmasi-stub}}
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