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Anemia sel sabit: Perbedaan antara revisi

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Muhammad Anas Sidik (bicara | kontrib)
24.329 suntingan
Tidak ada ringkasan suntingan
Tag: halaman dengan galat kutipan Suntingan perangkat seluler Suntingan peramban seluler Suntingan seluler lanjutan
Muhammad Anas Sidik (bicara | kontrib)
24.329 suntingan
Tidak ada ringkasan suntingan
Tag: Suntingan perangkat seluler Suntingan peramban seluler Suntingan seluler lanjutan
 
(12 revisi perantara oleh pengguna yang sama tidak ditampilkan)
Baris 1:
{{Penyangkalan-medis}}{{one source|date=Oktober 2020}}
{{Infobox medical condition (new)
| name = Anemia sel sabit
| image = Sickle cell 01.jpg
| caption = Gambar A menunjukkan sel darah merah normal yang mengalir bebas melalui pembuluh darah. Sisipan menunjukkan penampang sel darah merah normal dengan hemoglobin normal. Gambar B menunjukkan sel darah merah abnormal berbentuk sabit yang menempel di titik percabangan dalam pembuluh darah. Gambar sisipan menunjukkan penampang sel sabit dengan untaian hemoglobin sabit (HbS) polimerisasi panjang yang meregang dan mengubah bentuk sel hingga tampak seperti bulan sabit.
| caption = Figure (A) shows normal red blood cells flowing freely through a blood vessel. The inset shows a cross-section of a normal red blood cell with normal [[haemoglobin]]. Figure (B) shows abnormal, sickled red blood cells sticking at the branching point in a blood vessel. The inset image shows a cross-section of a sickle cell with long polymerized sickle haemoglobin (HbS) strands stretching and distorting the cell shape to look like a crescent moon.
| field = [[HematologyHematologi]], [[medicalgenetika geneticskedokteran]]
| synonyms = SicklePenyakit cellsel disordersabit; drepanocytosisdrepanositosis ''(datedtertanggal)''
| symptoms = Serangan nyeri, [[anemia]], pembengkakan di tangan dan kaki, infeksi bakteri, [[strok]]<ref name=NIH2015Sign>{{cite web|title=What Are the Signs and Symptoms of Sickle Cell Disease?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/signs|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160309034557/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/signs|archive-date=9 March 2016}}</ref>
| symptoms = Attacks of pain, [[anemia]], [[Dactylitis|swelling in the hands and feet]], [[bacterial infection]]s, [[stroke]]<ref name=NIH2015Sign/>
| complications = [[Sakit kronis]], strok, nekrosis tulang aseptik, [[batu empedu]], ulkus kaki, [[priapisme]], [[hipertensi paru]], masalah penglihatan, masalah ginjal.<ref name=NIH2015What>{{cite web|title=What Is Sickle Cell Disease?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160306021706/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/|archive-date=6 March 2016}}</ref>
| complications = [[Chronic pain]], [[stroke]], [[aseptic bone necrosis]], [[gallstones]], [[leg ulcers]], [[priapism]], [[pulmonary hypertension]], vision problems, [[kidney problems]]<ref name=NIH2015What/>
| onset = Usia 5–6 months of agebulan<ref name=NIH2015Sign/>
| duration =
| causes = Genetik, Mutasi homozigot pada gen hemoglobin S.<ref name=NIH2015Caus>{{cite web|title=What Causes Sickle Cell Disease?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/causes|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160324034054/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/causes|archive-date=24 March 2016}}</ref>
| causes = Genetic, [[Homozygous]] mutation in the [[hemoglobin S]] gene.<ref name=NIH2015Caus/>
| risks =
| diagnosis = [[uji darah]]<ref name=NIH2015Diag>{{cite web|title=How Is Sickle Cell Disease Diagnosed?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/diagnosis|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160309032258/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/diagnosis|archive-date=9 March 2016}}</ref>
| diagnosis = [[Blood test]]<ref name=NIH2015Diag/>
| differential =
| prevention =
| treatment = [[Vaksinasi]], [[antibiotik]], asupan cairan tinggi, suplementasi [[asam folat]], obat [[analgesik|pereda nyeri]], [[transfusi darah]]<ref name=WHO2011>{{cite web|title=Sickle-cell disease and other haemoglobin disorders Fact sheet N°308|url=https://www.who.int/mediacentre/factsheets/fs308/en/|access-date=8 March 2016|date=January 2011|url-status=dead|archive-url=https://web.archive.org/web/20160309034307/http://www.who.int/mediacentre/factsheets/fs308/en/|archive-date=9 March 2016}}</ref><ref name=NIH2015Tx>{{cite web|title=How Is Sickle Cell Disease Treated?|url=http://www.nhlbi.nih.gov/health/health-topics/topics/sca/treatment|website=National Heart, Lung, and Blood Institute|access-date=8 March 2016|date=12 June 2015|url-status=live|archive-url=https://web.archive.org/web/20160309042159/http://www.nhlbi.nih.gov/health/health-topics/topics/sca/treatment|archive-date=9 March 2016}}</ref>
| treatment = [[Vaccination]], [[antibiotic]]s, high fluid intake, [[folic acid]] supplementation, [[pain medication]], [[blood transfusion]]s<ref name=WHO2011/><ref name=NIH2015Tx/>
| medication =
| prognosis = [[LifeHarapan expectancyhidup]] 40–60 yearstahun (developednegara worldmaju)<ref name=NIH2015What/>
| frequency = 4,4 juta (2015)<ref name=GBD2015Pre>{{cite journal | vauthors = Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, Carter A, etal | collaboration = GBD 2015 Disease and Injury Incidence and Prevalence Collaborators | title = Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 | journal = Lancet | volume = 388 | issue = 10053 | pages = 1545–1602 | date = October 2016 | pmid = 27733282 | pmc = 5055577 | doi = 10.1016/S0140-6736(16)31678-6 }}</ref>
| frequency = 4.4 million (2015)<ref name=GBD2015Pre/>
| deaths = 114,800 (2015)<ref name=GBD2015De>{{cite journal | vauthors = Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, Carter A, etal | collaboration = GBD 2015 Mortality and Causes of Death Collaborators | title = Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015 | journal = Lancet | volume = 388 | issue = 10053 | pages = 1459–1544 | date = October 2016 | pmid = 27733281 | pmc = 5388903 | doi = 10.1016/S0140-6736(16)31012-1 }}</ref>
| deaths = 114,800 (2015)<ref name=GBD2015De/>
}}
'''Anemia sel sabit''' atau '''penyakit sel sabit''' adalah kondisi serius di mana sel-[[sel darah merah|sel-sel darah merah]] menjadi berbentuk [[bulan sabit]], seperti huruf [[C]]. Sel darah merah normal berbentuk donat tanpa lubang (lingkaran, pipih di bagian tengahnya), sehingga memungkinkan mereka melewati [[pembuluh darah]] dengan mudah dan memasok [[oksigen]] bagi seluruh bagian tubuh. Sulit bagi sel darah merah berbentuk bulan sabit untuk melewati pembuluh darah terutama di bagian [[pembuluh darah]] yang jadi menyempit dengan sendirinya, karena sel darah merah ini akan tersangkut dan akan menimbulkan rasa [[nyeri]], [[infeksi]] serius, dan kerusakan organ pada tubuh.
 
== Penyebab ==
Diperoleh dari "https://wiki-indonesia.club/wiki/Anemia_sel_sabit"