Reaksi Grignard: Perbedaan antara revisi

'''Reaksi Grignard''' (pengucapan <span class="IPA" title="Representation in the International Phonetic Alphabet (IPA)" contenteditable="false">/ɡriɲar/</span>) adalah suatu [[reaksi kimia]] [[Kimia organologam|organologam]] yang mana [[alkil]], [[vinil]], atau aril-[[magnesium]] [[halida]] ('''pereaksi Grignard''') ditambahkan ke dalam gugus [[karbonil]] dari suatu aldehida atau keton.<ref>{{March6th}}</ref><ref>[http://www.mhhe.com/physsci/chemistry/carey/student/olc/ch19reactioncarboxylicacids.html Chapter 19: Carboxylic Acids]. Organic Chemistry 4e Carey. mhhe.com </ref> Reaksi ini adalah suatu cara penting untuk pembuatan [[Ikatan karbon-karbon|ikatan karbon–karbon]].<ref>{{cite journal|last = Shirley|first = D. A.|year = 1954|title = The Synthesis of Ketones from Acid Halides and Organometallic Compounds of Magnesium, Zinc, and Cadmium|journal = [[Org. React.]]|volume = 8|pages = 28–58}}</ref><ref>{{cite book|last = Huryn|first = D. M.|year = 1991|title = Comprehensive Organic Synthesis, Volume 1: Additions to C—X π-Bonds, Part 1|pages = 49–75|chapter = Carbanions of Alkali and Alkaline Earth Cations: (ii) Selectivity of Carbonyl Addition Reactions|editor1-last = Trost|editor1-first = B. M.|editor2-last = Fleming|editor2-first = I.|isbn = 978-0-08-052349-1|editor1-link = Barry Trost|editor2-link = Ian Fleming (kimiawan)|publisher = [[Elsevier Science]]|doi = 10.1016/B978-0-08-052349-1.00002-0|language=en}}</ref> Reaksi antara suatu halida organik dengan magnesium ''bukan'' reaksi Grignard, tetapi menghasilkan pereaksi Grignard.<ref>IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997). ISBN 0-9678550-9-8. {{DOI|10.1351/goldbook}}. </ref>

 

|author = [[Victor Grignard|Grignard, V.]]|title = Sur quelques nouvelles combinaisons organométaliques du magnésium et leur application à des synthèses d'alcools et d'hydrocabures|journal = Compt. Rend.|year = 1900|volume = 130|pages = 1322–25|url = http://gallica.bnf.fr/ark:/12148/bpt6k3086n/f1322.table|language=en}}</ref> Pereaksi Grignard mirip dengan [[pereaksi organolitium]] karena keduanya merupakan nukleofil kuat yang dapat membentuk ikatan karbon–karbon baru.