Naby Keïta bergabung bersama klub tanah kelahirannya [[Horoya AC]] pada umur sembilan tahun.<ref name="Ten things on RB Leipzig's new African star Naby Keita">{{cite web|title=Ten things on RB Leipzig's new African star Naby Keita|url=http://www.bundesliga.com/en/news/Bundesliga/noblsp-ten-things-on-rb-leipzigs-new-african-star-naby-keita.jsp|website=Bundesliga|accessdate=18 Desember 2016}}</ref>
