Protein Kinase B: Perbedaan antara revisi
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{{Redirect|AKT}}
{{infobox protein
|Name=[[AKT1]]
|image=Crystal structure of Akt-1-inhibitor complexes.png
|caption=Representasi pita dari struktur kristal kompleks ''Akt-1-inhibitor''.<ref name="pmid20481595">{{PDB|3MV5}}; {{cite journal | vauthors = Freeman-Cook KD, Autry C, Borzillo G, Gordon D, Barbacci-Tobin E, Bernardo V, Briere D, Clark T, Corbett M, Jakubczak J, Kakar S, Knauth E, Lippa B, Luzzio MJ, Mansour M, Martinelli G, Marx M, Nelson K, Pandit J, Rajamohan F, Robinson S, Subramanyam C, Wei L, Wythes M, Morris J | display-authors = 6 | title = Design of selective, ATP-competitive inhibitors of Akt | journal = Journal of Medicinal Chemistry | volume = 53 | issue = 12 | pages = 4615–22 | date = June 2010 | pmid = 20481595 | doi = 10.1021/jm1003842 }}</ref>
|width=
|HGNCid=391
|Symbol=[[AKT1]]
|AltSymbols=
|EntrezGene=207
|OMIM=164730
|RefSeq=NM_005163
|UniProt=P31749
|PDB=
|ECnumber=
|Chromosome=14
|Arm=q
|Band=32.32
|LocusSupplementaryData=-32.33
}}
{{infobox protein
|Name=[[AKT2]]
|image=3D0E Ribbon.png
|caption=Struktur kristal kompleks ''Akt-2-inhibitor''.<ref name="pmid18800763">{{PDB|3D0E}}; {{cite journal | vauthors = Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, Strum SL, Wood ER, Duckett DR, Eberwein D, Knick VB, Lansing TJ, McConnell RT, Zhang S, Minthorn EA, Concha NO, Warren GL, Kumar R | display-authors = 6 | title = Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase | journal = Journal of Medicinal Chemistry | volume = 51 | issue = 18 | pages = 5663–79 | date = September 2008 | pmid = 18800763 | doi = 10.1021/jm8004527 | url = https://figshare.com/articles/Identification_of_4_2_4_Amino_1_2_5_oxadiazol_3_yl_1_ethyl_7_3_i_S_i_3_piperidinylmethyl_oxy_1_i_H_i_imidazo_4_5_i_c_i_pyridin_4_yl_2_methyl_3_butyn_2_ol_GSK690693_a_Novel_Inhibitor_of_AKT_Kinase/2911615 }}</ref>
|HGNCid=392
|Symbol=[[AKT2]]
|AltSymbols=
|EntrezGene=208
|OMIM=164731
|RefSeq=NM_001626
|UniProt=P31751
|PDB=
|ECnumber=
|Chromosome=19
|Arm=q
|Band=13.1
|LocusSupplementaryData=-13.2
}}
{{infobox protein
|Name=[[AKT3]]
|caption=
|image=
|width=
|HGNCid=393
|Symbol=[[AKT3]]
|AltSymbols=
|EntrezGene=10000
|OMIM=611223
|RefSeq=NM_181690
|UniProt=Q9Y243
|PDB=
|ECnumber=
|Chromosome=1
|Arm=q
|Band=43
|LocusSupplementaryData=-44
}}
'''Kinase PB''' ({{lang-en|protein kinase b, PKB, RAC, Akt}}) adalah [[kinase protein]] dari golongan [[kinase AGC]] yang menyebabkan inaktivasi [[glikogen sintase kinase-3]].<ref name="hem-ref">{{en}} {{cite web
| url = http://www.cloetta-stiftung.ch/hemmings-ref.pdf
| |||