Amlodipin: Perbedaan antara revisi

Amlodipin paling sering digunakan untuk mengobati [[Tekanan darah tinggi|hipertensi]] sistemik pada kucing dan anjing.<ref name="papich">{{Cite book|title=Saunders Handbook of Veterinary Drugs|last=Papich|first=Mark G.|date=2007|publisher=Saunders/Elsevier|isbn=9781416028888|edition=2nd|location=St. Louis, Mo|pages=26–27|chapter=Amlodipine Besylate}}</ref> Pada kucing, obat ini merupakan pengobatan lini pertama karena kemanjurannya dan sedikit efek samping.<ref>{{Cite journal|last=Henik|first=RA|last2=Snyder|first2=PS|last3=Volk|first3=LM|date=28 August 2014|title=Treatment of systemic hypertension in cats with amlodipine besylate|journal=Journal of the American Animal Hospital Association|language=en|volume=33|issue=3|pages=226–234|doi=10.5326/15473317-33-3-226|pmid=9138233}}</ref> [[Tekanan darah tinggi|Hipertensi]] sistemik pada kucing biasanya sekunder akibat kelainan lain, seperti [[Gagal ginjal kronis|penyakit ginjal kronis]], dan amlodipin paling sering diberikan pada kucing dengan [[Nefropati|penyakit ginjal]].<ref name="diamondback">{{Cite web|url=http://www.diamondbackdrugs.com/treating-high-blood-pressure-with-amlodipine/|title=Amlodipine in Veterinary Medicine|last=Diamondback Drugs|archive-url=https://web.archive.org/web/20170811011323/http://www.diamondbackdrugs.com/treating-high-blood-pressure-with-amlodipine/|archive-date=11 August 2017|access-date=29 June 2017|url-status=live}}</ref> Walaupun amlodipin digunakan pada anjing dengan hipertensi sistemik, amlodipin tidak manjur. Amlodipin juga digunakan untuk mengobati [[Gagal jantung|gagal jantung kongestif]] karena [[ Regurgitasi katup mitral|regurgitasi katup mitral]] pada anjing.<ref>{{Cite journal|last=Atkins|first=C.|last2=Bonagura|first2=J.|last3=Ettinger|first3=S.|last4=Fox|first4=P.|last5=Gordon|first5=S.|last6=Haggstrom|first6=J.|last7=Hamlin|first7=R.|last8=Keene|first8=B.|last9=Luis-Fuentes|first9=V.|date=1 November 2009|title=Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease|journal=Journal of Veterinary Internal Medicine|language=en|volume=23|issue=6|pages=1142–1150|doi=10.1111/j.1939-1676.2009.0392.x|issn=1939-1676|pmid=19780929}}</ref> Dengan mengurangi resistensi terhadap aliran maju dalam sirkulasi sistemik, menghasilkan penurunan aliran regurgitasi ke [[Atrium (anatomi)|atrium kiri]].<ref>{{Cite journal|last=Suzuki|first=Shuji|last2=Fukushima|first2=Ryuji|last3=Ishikawa|first3=Taisuke|last4=Yamamoto|first4=Yuta|last5=Hamabe|first5=Lina|last6=Kim|first6=Soomin|last7=Yoshiyuki|first7=Rieko|last8=Machida|first8=Noboru|last9=Tanaka|first9=Ryou|date=18 September 2012|title=Comparative effects of amlodipine and benazepril on Left Atrial Pressure in Dogs with experimentally-induced Mitral Valve Regurgitation|journal=BMC Veterinary Research|volume=8|pages=166|doi=10.1186/1746-6148-8-166|issn=1746-6148|pmc=3489586|pmid=22989022}}</ref> Demikian pula, obat dapat digunakan pada anjing dan kucing dengan lesi shunting kiri-ke-kanan seperti [[defek septum ventrikel]] untuk mengurangi shunt. Efek samping jarang terjadi pada kucing. Pada anjing, efek samping utamanya adalah [[ Hiperplasia gingiva|hiperplasia gingiva]].<ref name="wedgewood">{{Cite web|url=http://www.wedgewoodpetrx.com/learning-center/professional-monographs/amlodipine-for-veterinary-use.html|title=Amlodipine for Veterinary Use|last=Forney|first=Barbara|website=Wedgewood Pharmacy|archive-url=https://web.archive.org/web/20170627172329/http://www.wedgewoodpetrx.com/learning-center/professional-monographs/amlodipine-for-veterinary-use.html|archive-date=27 June 2017|access-date=29 June 2017|url-status=live}}</ref>

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[[Kategori:Obat]]