Pada 17 Februari 2020, sebanyak 13 orang Amerika dipulangkan ke [[Pusat Medis Universitas Nebraska]] dari [[ Pandemi COVID-19 tentang Puteri Intan|''Princess Diamond'']] di lepas pantai Jepang. Sepuluh dinyatakan positif, dan tiga lainnya terpapar. Tiga hari kemudian, sebelas dari orang-orang ini dinyatakan positif.<ref>{{Cite web|url=https://www.omaha.com/livewellnebraska/coronavirus-timeline-how-the-pandemic-unfolded-in-omaha/article_314fcd77-1b53-5bfb-be0b-49bd3bf98ae3.html|title=Coronavirus timeline: How the pandemic unfolded in Omaha|first=World-Herald|website=Omaha.com|language=en|access-date=2020-05-18}}</ref><ref>{{Cite web|url=https://github.com/nytimes/covid-19-data|title=Coronavirus (Covid-19) Data in the United States|website=GitHub|publisher=New York Times|language=en|access-date=2020-05-18}}</ref>
===Maret===
Pada 6 Maret 2020, Gubernur [[Pete Ricketts]] mengumumkan kasus dugaan pertama Nebraska, seorang wanita berusia 36 tahun dari Omaha yang baru saja kembali dari perjalanan ke Inggris.<ref>{{Cite web|url=http://netnebraska.org/article/news/1211887/nebraska-confirms-first-covid-19-case|title=Nebraska Confirms First COVID-19 Case|last=Kelly|first=Bill|last2=|first2=|date=2020-03-06|website=[[Nebraska Educational Telecommunications|NET]] News|language=en|archive-url=https://web.archive.org/web/20200430092521/http://netnebraska.org/article/news/1211887/nebraska-confirms-first-covid-19-case|archive-date=2020-04-30|access-date=2020-05-14|url-status=live|dead-url=yes}}</ref> Pada 19 Maret 2020, Ricketts mulai mengadakan pembatasan perdagangan dan pertemuan publik melalui sistem "Directed Health Measures" (DHM), pada masing-masing kabupaten berdasarkan jumlah infeksi aktif di suatu wilayah.<ref name=":9">{{Cite web|url=https://www.1011now.com/content/news/Directed-Health-Measures-announced-for--569180461.html|title=DHHS announces new Directed Health Measures for several Nebraska counties|last=|first=|date=|website=10/11 Now|language=english|archive-url=|archive-date=|access-date=2020-05-14|url-status=live}}</ref><ref name=":5">{{Cite web|url=https://nebraska.tv/news/local/ricketts-announces-direct-health-measure-for-remaining-counties|title=Ricketts announces Direct Health Measure for remaining counties|last=|first=|date=2020-04-03|website=[[KHGI-TV|Nebraska.tv]]|publisher=Sinclair Broadcast Group|archive-url=|archive-date=|access-date=2020-05-14|url-status=live}}</ref> Dua kematian pertama Nebraska diumumkan pada 27 Maret; negara telah mencapai 83 kasus yang terkonfirmasi.<ref>{{Cite web|url=https://www.ketv.com/article/nebraskas-first-covid-19-death-confirmed/31959606|title=2 deaths from COVID-19 reported in Nebraska|first=|date=2020-03-27|website=KETV|publisher=Hearst Television|language=en|archive-url=|archive-date=|access-date=2020-05-14|url-status=live}}</ref><ref name=":4">{{Cite web|url=https://www.wowt.com/content/news/Nebraska-COVID-19-response-update-for-March-27-2020-569163291.html|title=Nebraska Gov. Ricketts waives healthcare license restrictions, fees|last=|first=|date=|website=WOWT 6 News|language=EN-US|archive-url=|archive-date=|access-date=2020-05-14|url-status=live}}</ref> Kematian ketiga diumumkan pada 30 Maret, diikuti oleh kematian keempat pada hari berikutnya.<ref>{{Cite web|url=https://www.omaha.com/livewellnebraska/health/nebraska-records-third-coronavirus-death-a-lincoln-county-man-in-his-90s/article_c657bd66-76dd-57e9-949d-05d0425b47e0.html|title=Nebraska records third coronavirus death, a Lincoln County man in his 90s|last=Gaarder|first=Nancy|date=|website=Omaha.com|language=en|archive-url=|archive-date=|access-date=2020-05-14|url-status=live}}</ref><ref>{{Cite web|url=https://www.omaha.com/livewellnebraska/health/nebraska-records-fourth-covid-19-death-a-buffalo-county-man-in-his-90s/article_9da31468-48e7-5dab-9b97-6fb6ba67b574.html|title=Nebraska records fourth COVID-19 death, a Buffalo County man in his 90s|last=Gaarder|first=Nancy World|date=|website=Omaha.com|language=en|archive-url=|archive-date=|access-date=2020-05-15|url-status=live}}</ref>
===April===
Kematian kelima dikonfirmasi pada 1 April<ref>{{Cite web|url=https://journalstar.com/news/local/nebraskas-fifth-death-from-covid-19-reported/article_919aa474-4be3-5a7d-a318-e14b016b8cd0.html|title=Nebraska's fifth death from COVID-19 reported|last=Sangimino|first=Pat|website=JournalStar.com|language=en|access-date=2020-05-15}}</ref> diikuti dengan kematian yang lain pada 2 April (juga kasus pertama di [[ Gage County, Nebraska|Kabupaten Gage]]).<ref>{{Cite web|url=https://www.newsrepublican.com/news/20200403/sixth-nebraska-covid-19-death-reported|title=Sixth Nebraska COVID-19 death reported|website=Boone News-Republican|language=en|access-date=2020-05-15}}</ref> Dua kematian baru dikonfirmasi pada 4 April, keduanya di Kabupaten Douglas; jumlah total kasus yaitu 321.<ref>{{Cite web|url=https://www.wowt.com/content/news/Nebraska-COVID-19-cases-reported-Saturday-April-4-2020-569382011.html|title=Nebraska COVID-19 case update: 2 more deaths reported in Douglas County|last=|first=|date=|website=WOWT News 6|language=english|archive-url=|archive-date=|access-date=2020-05-15|url-status=live}}</ref> Pada 7 April, empat kematian baru diumumkan, dengan dua di Kabupaten Douglas, dan masing-masing satu dari kabupaten [[ Custer County, Nebraska|Custer]] dan [[ Hall County, Nebraska|Hall]].<ref>{{Cite web|url=https://www.wowt.com/content/news/Nebraska-COVID-19-cases-reported-Tuesday-April-7-2020-569444601.html|title=Nebraska COVID-19 update: Douglas County Health center confirms 2nd death; county reports 8 new cases|last=|first=|date=|website=WOWT News 6|language=english|archive-url=|archive-date=|access-date=2020-05-15|url-status=live}}</ref> Pada 9 April, keadaan telah mencapai 577 kasus dan 15 kematian.<ref name=":10">{{Cite web|url=https://www.omaha.com/news/state_and_regional/ricketts-urges-nebraskans-to-stay-home-for-21-days-to-really-knock-this-virus-down/article_8a59ce8d-3f04-588c-9357-7b95a7a1539c.html|title=Ricketts urges Nebraskans to stay home for 21 days to 'really knock this virus down'|last=Stoddard|first=Martha|date=2020-04-10|website=Omaha.com|language=en|archive-url=|archive-date=|access-date=2020-05-15|url-status=live}}</ref> Pada 17 April, jumlah kasus di seluruh negara bagian telah melampaui 1000.<ref>{{Cite web|url=https://www.omaha.com/livewellnebraska/nebraska-coronavirus-cases-top-1-000-two-more-deaths-reported/article_88303ca3-b94a-58b3-9428-07c5255daaa4.html|title=Nebraska coronavirus cases top 1,000; two more deaths reported|last=Gaarder|first=Nancy|date=2020-04-17|website=Omaha World-Herald|language=en|archive-url=|archive-date=|access-date=2020-05-15|url-status=live}}</ref> Pada pertengahan April, lonjakan penting dalam kasus yang dikaitkan dengan pabrik [[ Industri pengemasan daging|pengepakan daging]] mulai muncul; pada 21 April, 237 kasus telah dikaitkan dengan fasilitas [[ JBS USA|JBS]] di [[Grand Island]], terhitung sekitar 40% dari semua kasus di wilayah Departemen Kesehatan Distrik Tengah.<ref>{{Cite web|url=https://www.omaha.com/news/state_and_regional/237-coronavirus-cases-tied-to-jbs-beef-plant-in-grand-island-disease-specialists-are-touring/article_2894db56-913a-5c61-a065-6860a8ae50ad.html|title=237 coronavirus cases tied to JBS beef plant in Grand Island; disease specialists are touring plants|last=Duffy|first=Erin|date=2020-04-21|website=Omaha World-Herald|language=en|archive-url=|archive-date=|access-date=2020-05-15|url-status=live}}</ref> Pada 28 April, kasus di Nebraska telah mencapai total 3.374 kasus.<ref>{{Cite web|url=https://www.omaha.com/livewellnebraska/new-nebraska-coronavirus-cases-include-36-in-grand-island-area-16-in-douglas-county/article_d202580c-ae88-5e75-a217-f6e480cf4765.html|title=New Nebraska coronavirus cases include 36 in Grand Island area, 16 in Douglas County|last=Gaarder|first=Nancy|date=2020-04-28|website=Omaha.com|language=en|archive-url=|archive-date=|access-date=2020-05-15|url-status=live}}</ref>
