Venlafaksin: Perbedaan antara revisi
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{{Infobox drug|drug_name=|image=Venlafaxine structure.svg|alt=|image2=Venlafaxine-3D-balls.png|caption=<!-- | type = mab / vaccine / combo -->|type=<!-- Names -->|tradename=Effexor, Efexor, others<ref name=brands />|synonyms=|IUPAC_name=(''RS'')-1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]cyclohexanol
<!-- Clinical data -->|pregnancy_AU=B2|pregnancy_US=C|pregnancy_category=|routes_of_administration=By mouth|Drugs.com={{drugs.com|monograph|Venlafaxine_Hydrochloride}}|MedlinePlus=<!-- Legal data -->|legal_AU=S4|legal_CA=Rx-only|legal_UK=POM|legal_US=Rx-only|legal_status=|DailyMedID=Venlafaxine|licence_US=|licence_EU=<!-- Pharmacokinetic data -->|bioavailability=42±15%<ref name=TGA>{{cite web |title=Apo-Venlafaxine XR Capsules |work=TGA eBusiness Services |publisher=Apotex Pty Ltd |place=Macquarie Park, NSW |date=13 April 2012 |accessdate=6 November 2013 |url=https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2012-PI-01095-3 |format=PDF |archive-date=19 April 2018 |archive-url=https://web.archive.org/web/20180419100649/https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2012-PI-01095-3 |url-status=live }}</ref>|protein_bound=27±2% (parent compound), 30±12% (active metabolite, [[desvenlafaxine]])<ref name=DM>{{cite web |title=Venlafaxine (venlafaxine hydrochloride) tablet [Aurobindo Pharma Limited] |work=DailyMed |publisher=Aurobindo Pharma Limited |date=February 2013 |accessdate=6 November 2013 |url=http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b23637e5-d37f-41b5-ba76-fc053e903bc2 |archive-date=30 January 2020 |archive-url=https://web.archive.org/web/20200130180552/https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b23637e5-d37f-41b5-ba76-fc053e903bc2 |url-status=live }}</ref>|metabolism=Extensively metabolised by the [[liver]]<ref name=TGA
<!-- Chemical and physical data -->|C=17|H=27|N=1|O=2|smiles=OC2(C(c1ccc(OC)cc1)CN(C)C)CCCCC2|StdInChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3|StdInChI_Ref={{stdinchicite|correct|chemspider}}|StdInChIKey=PNVNVHUZROJLTJ-UHFFFAOYSA-N|StdInChIKey_Ref={{stdinchicite|correct|chemspider}}}}
'''Venlafaxine''' adalah obat [[antidepresan]] golongan dari serotonin-norepinefrin reuptake inhibitor (SNRI). <ref name="AHFS2018">{{Cite web|title=Venlafaxine Hydrochloride Monograph for Professionals|url=https://www.drugs.com/monograph/venlafaxine-hydrochloride.html|website=Drugs.com|publisher=AHFS|archive-url=https://web.archive.org/web/20201127001402/https://www.drugs.com/monograph/venlafaxine-hydrochloride.html|archive-date=27 November 2020|access-date=24 December 2018|url-status=live}}</ref> Obat ini digunakan untuk mengatasi [[gangguan depresi mayor]] (MDD), [[Gangguan kecemasan menyeluruh|gangguan kecemasan umum]] (GAD), gangguan panik, dan [[Gangguan kecemasan sosial|fobia sosial]] . <ref name="AHFS2018"
Kejadian efek samping yang umum terjadi seperti hilangnya nafsu makan, [[sembelit]], [[xerostomia]], [[pusing]], berkeringat, dan gangguan seksual. <ref name="AHFS2018"
Obat venlafaxine sendiri disetujui penggunaannya dalam medis di Amerika Serikat ditahun 1993. <ref name="AHFS2018" />
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