Sukralfat: Perbedaan antara revisi
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{{Short description|Chemical compound and gastrointestinal medication}}
{{Use dmy dates|date=August 2021}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 405746645
| image = Sucralfate.svg
| width = 350
<!-- Clinical data -->
| tradename = Carafate, dll
| Drugs.com = {{drugs.com|monograph|sucralfate}}
| MedlinePlus = a681049
| DailyMedID = Sucralfate
| pregnancy_category =
| routes_of_administration = [[oral]], & rektal
| ATC_prefix = A02
| ATC_suffix = BX02
| ATC_supplemental =
| legal_US = Rx-only
| legal_US_comment = <ref name="Carafate FDA label" />
| legal_status = Rx-only
<!-- Pharmacokinetic data -->
| bioavailability = 3-5% (lokal)
| protein_bound =
| metabolism = [[saluran pencernaan]]; [[hati]]: tidak diketahui
| elimination_half-life = tidak diketahui
| excretion = [[Feses]], [[urin]]
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 54182-58-0
| PubChem = 6398525
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB00364
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4911161
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = XX73205DH5
| KEGG = C07314
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 611727
<!--Chemical data-->
| IUPAC_name = Heksadeka-μ-hidroksitetrakosahidroksi[μ<sub>8</sub>-[1,3,4,6-tetra-''O''-sulfo-β-<small>D</small>fruktofuranosil-α-<small>D</small>-glukopiranosida tetrakis(hidrogen sulfat)8-)<nowiki>]]</nowiki>heksadekaaluminum<ref name="Merck">''[[Merck Index]]'', 12th Edition, '''9049'''.</ref>
| C=12 | H=54 | Al=16 | O=75 | S=8
}}
'''Sukralfat''' adalah obat yang digunakan untuk mengobati [[tukak lambung]], [[penyakit refluks gastroesofagus]] (GERD), proktitis radiasi, [[maag]], serta untuk mencegah tukak stres.<ref name=AHFS2019/><ref name=Mat2003>{{cite journal | vauthors = Maton PN | title = Profile and assessment of GERD pharmacotherapy | journal = Cleveland Clinic Journal of Medicine | volume = 70 | pages = S51-70 | date = November 2003 | issue = Suppl 5 | pmid = 14705381 | doi = 10.3949/ccjm.70.Suppl_5.S51 }}</ref><ref name=Brad2014/> Kegunaannya pada orang yang terinfeksi bakteri ''[[Helicobacter pylori]]'' terbatas.<ref name=AHFS2019/> Obat ini digunakan melalui mulut (untuk tukak saluran cerna bagian atas) dan rektal (untuk proktitis radiasi).<ref name=AHFS2019>{{cite web |title=Sucralfate Monograph for Professionals |url=https://www.drugs.com/monograph/sucralfate.html |website=Drugs.com |publisher=American Society of Health-System Pharmacists |date=22 May 2023}}</ref><ref name=Brad2014>{{cite journal | vauthors = Mendenhall WM, McKibben BT, Hoppe BS, Nichols RC, Henderson RH, Mendenhall NP | s2cid = 12129192 | title = Management of radiation proctitis | journal = American Journal of Clinical Oncology | volume = 37 | issue = 5 | pages = 517–23 | date = October 2014 | pmid = 23241500 | doi = 10.1097/COC.0b013e318271b1aa }}</ref>
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