Pada 28 Agustus 2024, Twisters telah meraup US$250,4 juta di [[Amerika Serikat]] dan [[Kanada]], dan US$98,7 juta di wilayah lain, dengan total US$349,1 juta di seluruh dunia.<ref>{{cite web|url=https://www.boxofficemojo.com/date/2024-07-19/|title=Domestic Box Office For Jul 19, 2024|website=[[Box Office Mojo]]|access-date=July 28, 2024|archive-date=July 27, 2024|archive-url=https://web.archive.org/web/20240727062521/https://www.boxofficemojo.com/date/2024-07-19/|url-status=live}}</ref>
Di Amerika Serikat dan Kanada, Twisters awalnya diproyeksikan menghasilkan pendapatan kotor US$40–55 juta dari 4.151 bioskop pada akhir pekan pembukaannya. Setelah menghasilkan $32,1 juta pada hari pertama,[47] termasuk perkiraan $10,7 juta dari pratinjau Rabu dan Kamis, proyeksi dinaikkan menjadi $75 juta. Film tersebut kemudian debut dengan pendapatan $81,3 juta, akhir pekan pembukaan terbaik untuk film bencana alam, melampaui [[The Day After Tomorrow]] (2004).<ref name="BOProjections">{{cite web |last1=Rubin |first1=Rebecca |title=Box Office: ''Twisters'' Aims to Stir Up $55 Million Debut |url=https://variety.com/2024/film/news/twisters-box-office-opening-weekend-estimate-1236073914/ |website=[[Variety (magazine)|Variety]] |access-date=17 July 2024 |date=17 July 2024 |archive-date=July 28, 2024 |archive-url=https://web.archive.org/web/20240728231309/https://variety.com/2024/film/news/twisters-box-office-opening-weekend-estimate-1236073914/ |url-status=live }}</ref><ref>{{cite web|url=https://www.hollywoodreporter.com/movies/movie-news/twisters-category-5-storm-box-office-debut-1235950724/|title=Box Office: ''Twisters'' Hopes to Whip Up Category 5 Storm in U.S. Debut|date=July 17, 2024|first=Pamela|last=McClintock|website=[[The Hollywood Reporter]]|access-date=July 19, 2024|archive-date=July 18, 2024|archive-url=https://web.archive.org/web/20240718230059/https://www.hollywoodreporter.com/movies/movie-news/twisters-category-5-storm-box-office-debut-1235950724/|url-status=live}}</ref>
