Pravastatin: Perbedaan antara revisi

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Muhammad Anas Sidik (bicara | kontrib)
Tidak ada ringkasan suntingan
Tag: Suntingan perangkat seluler Suntingan peramban seluler Suntingan seluler lanjutan
Muhammad Anas Sidik (bicara | kontrib)
Tidak ada ringkasan suntingan
Tag: Suntingan perangkat seluler Suntingan peramban seluler Suntingan seluler lanjutan
Baris 7:
 
<!-- Clinical data -->
| tradename = Pravachol, othersdll| Drugs.com = {{drugs.com|monograph|pravastatin-sodium}}
| Drugs.com = {{drugs.com|monograph|pravastatin-sodium}}
| MedlinePlus = a692025
| DailyMedID = Pravastatin
| pregnancy_AU = D
| routes_of_administration = [[Oral administration|By(rute mouthpemberian obat)|Oral]]
| ATC_prefix = C10
| ATC_suffix = AA03
Baris 30 ⟶ 29:
| bioavailability = 18%<ref name = PK>{{cite journal | vauthors = Neuvonen PJ, Backman JT, Niemi M | title = Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin | journal = Clinical Pharmacokinetics | volume = 47 | issue = 7 | pages = 463–474 | date = 2008 | pmid = 18563955 | doi = 10.2165/00003088-200847070-00003 | s2cid = 11716425 }}</ref>
| protein_bound = 50%<ref name = PK/>
| metabolism = [[LiverHati]] (minimal)<ref name = PK/>
| elimination_half-life = 1-3 hoursjam<ref name = PK/>
 
<!-- Identifiers -->
Baris 59 ⟶ 58:
 
<!-- Chemical and physical data -->
| IUPAC_name = (3''R'',5''R'')-3,5-dihydroxydihidroksi-7-((1''R'',2''S'',6''S'',8''R'',8a''R'')-6-hydroxyhidroksi-2-methylmetil-8-{[(2''S'')-2-methylbutanoylmetilbutanoil]oxyoksi}-1,2,6,7,8,8a-hexahydronaphthalenheksahidronaftalen-1-ylil)-heptanoicasam acidheptanoat
| C=23 | H=36 | O=7
| smiles = O=C(O)C[C@H](O)C[C@H](O)CC[C@H]2[C@H](/C=C\C1=C\[C@@H](O)C[C@H](OC(=O)[C@@H](C)CC)[C@@H]12)C