Apigenin: Perbedaan antara revisi

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Muhammad Anas Sidik (bicara | kontrib)
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Muhammad Anas Sidik (bicara | kontrib)
Tidak ada ringkasan suntingan
Tag: Suntingan perangkat seluler Suntingan peramban seluler Suntingan seluler lanjutan
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==Farmakologi==
Apigenin secara kompetitif mengikat situs benzodiazepin pada reseptor GABA<sub>A</sub>.<ref>{{Cite journal |last1=Viola |first1=H. |last2=Wasowski |first2=C. |last3=Levi de Stein |first3=M. |last4=Wolfman |first4=C. |last5=Silveira |first5=R. |last6=Dajas |first6=F. |last7=Medina |first7=J. H. |last8=Paladini |first8=A. C. |date=June 1995 |title=Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects |url=https://pubmed.ncbi.nlm.nih.gov/7617761/ |journal=Planta Medica |volume=61 |issue=3 |pages=213–216 |doi=10.1055/s-2006-958058 |issn=0032-0943 |pmid=7617761}}</ref> Ada temuan yang bertentangan mengenai bagaimana apigenin berinteraksi dengan situs ini.<ref>{{Cite journal |last1=Dekermendjian |first1=K. |last2=Kahnberg |first2=P. |last3=Witt |first3=M. R. |last4=Sterner |first4=O. |last5=Nielsen |first5=M. |last6=Liljefors |first6=T. |date=1999-10-21 |title=Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex |url=https://pubmed.ncbi.nlm.nih.gov/10543878/ |journal=Journal of Medicinal Chemistry |volume=42 |issue=21 |pages=4343–4350 |doi=10.1021/jm991010h |issn=0022-2623 |pmid=10543878}}</ref><ref>{{Cite journal |last1=Avallone |first1=R. |last2=Zanoli |first2=P. |last3=Puia |first3=G. |last4=Kleinschnitz |first4=M. |last5=Schreier |first5=P. |last6=Baraldi |first6=M. |date=2000-06-01 |title=Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla |url=https://pubmed.ncbi.nlm.nih.gov/10751547/ |journal=Biochemical Pharmacology |volume=59 |issue=11 |pages=1387–1394 |doi=10.1016/s0006-2952(00)00264-1 |issn=0006-2952 |pmid=10751547}}</ref> Apigenin dapat meningkatkan aktivitas enzim antioksidan endogen seperti SOD dan CAT, membantu mengurangi stres oksidatif.<ref>{{cite web |url=https://www.stanfordchem.com/top-6-benefits-of-apigenin-for-health.html |title=Top 6 Benefits of Apigenin for Health |last=Blanca |date=Aug 7, 2024 |website=Stanford Chemicals |access-date=Oct 16, 2024}}</ref><ref>{{cite journal |last1=Singh |first1=Abhinav |last2=Singh |first2=Jagjit |year=2024 |title=A comprehensive review of apigenin a dietary flavonoid: biological sources, nutraceutical prospects, chemistry and pharmacological insights and health benefits |journal=Critical Reviews in Food Science and Nutrition |pages=1–37 |doi=10.1080/10408398.2024.2390550|pmid=39154213 }}</ref>
 
==Biosintesis==
==Glikosida==