Orang dewasa berusia 20 tahun ke atas harus memeriksakan kolesterol setiap empat hingga enam tahun.[35]<ref name=":11">{{Cite web|title=What Your Cholesterol Levels Mean|url=https://www.goredforwomen.org/en/health-topics/cholesterol/about-cholesterol/what-your-cholesterol-levels-mean|website=www.goredforwomen.org|language=en|access-date=2020-04-30}}</ref> Kadar serum kolesterol Low[[lipoprotein Densitydensitas Lipoproteinrendah]] (LDL), kolesterol High[[lipoprotein Densitydensitas Lipoproteintinggi]] (HDL), dan trigliserida biasanya diuji dalam pengaturan perawatan primer menggunakan panel lipid.[36]<ref>{{Cite web|title=Cholesterol testing and results: MedlinePlus Medical Encyclopedia|url=https://medlineplus.gov/ency/patientinstructions/000386.htm|website=medlineplus.gov|language=en|access-date=2020-04-30}}</ref> Kadar kuantitatif lipoprotein dan trigliserida berkontribusi terhadap stratifikasi risiko penyakit kardiovaskular melalui model/kalkulator seperti ''Framingham Risk Score'', ''ACC/AHA Atherosclerotic Cardiovascular Disease Risk Estimator'', dan/atau ''Reynolds Risk Scores''. Model/kalkulator ini juga dapat memperhitungkan riwayat keluarga (penyakit jantung dan/atau kolesterol darah tinggi), usia, jenis kelamin, Indeks Massa Tubuh, riwayat medis (diabetes, kolesterol tinggi, penyakit jantung), kadar [[Protein C-reaktif|CRP]] sensitivitas tinggi, skor kalsium arteri koroner, dan indeks ''ankle-brachial''.[37]<ref name=":2">{{cite journal | vauthors = Kopin L, Lowenstein C | title = Dyslipidemia | journal = Annals of Internal Medicine | volume = 167 | issue = 11 | pages = ITC81–ITC96 | date = December 2017 | pmid = 29204622 | doi = 10.7326/AITC201712050 }}</ref> Stratifikasi kardiovaskular selanjutnya menentukan intervensi medis apa yang mungkin diperlukan untuk menurunkan risiko penyakit kardiovaskular di masa mendatang.[38]<ref>{{Cite journal |last=US Preventive Services Task Force |date=2022-08-23 |title=Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement |url=https://jamanetwork.com/journals/jama/fullarticle/2795521#:~:text=Recommendation%20The%20USPSTF%20recommends%20that,I%20statement) |journal=JAMA |volume=328 |issue=8 |pages=746–753 |doi=10.1001/jama.2022.13044 |pmid=35997723 |issn=0098-7484}}</ref>
