Protein transpor natrium-glukosa: Perbedaan antara revisi
Konten dihapus Konten ditambahkan
k bot Menambah: es:Proteínas con transporte sodio-glucosa, fr:Transporteur sodium-glucose |
→SGLT2: dev |
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==SGLT2==
SGLT2 ({{lang-en|Sodium/glucose cotransporter 2, Na<sup>+</sup>/glucose cotransporter 2, Low affinity sodium-glucose cotransporter, SLC5A2, SGLT2}}) merupakan [[glikoprotein]] dengan panjang 672 AA yang tergolong permease [[transporter glukosa]].
Mutasi pada SLC5A2 menyebabkan [[glukosuria]] pada [[ginjal]]<ref>{{en}}{{cite web
| url = http://www.uniprot.org/uniprot/P31639
| title = Reviewed, UniProtKB/Swiss-Prot P31639 (SC5A2_HUMAN)
| accessdate = 2010-05-08
| work = UniProt
}}</ref> dan [[aminoasiduria]].<ref>{{en}}{{cite web
| url = http://www.ncbi.nlm.nih.gov/pubmed/15610225
| title = A novel missense mutation in SLC5A2 encoding SGLT2 underlies autosomal-recessive renal glucosuria and aminoaciduria.
| accessdate = 2010-05-08
| work = Pediatric Nephrology Unit, Meyer Children's Hospital; Magen D, Sprecher E, Zelikovic I, Skorecki K.
}}</ref>
[[Tioglikosida]] merupakan inhibitors SGLT1 dan SGLT2, dan berpotensi mengontrol [[hiperglisemia]] pada penderita diabetes.<ref>{{en}}{{cite web
| url = http://www.ncbi.nlm.nih.gov/pubmed/17505558
| title = Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.
| accessdate = 2010-05-08
| work = Laboratory for Molecular Pathobiochemistry and Clinical Research, Max Planck Institute of Molecular Physiology; Castaneda F, Burse A, Boland W, Kinne RK.
}}</ref>
==Rujukan==
{{reflist}}
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