Amoksisilin: Perbedaan antara revisi
Konten dihapus Konten ditambahkan
Dibuat dengan menerjemahkan halaman "Amoxicillin" |
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Baris 1:
{{drugbox
| Watchedfields = changed
| verifiedrevid = 455343638
| drug_name = Amoksisilin
| IUPAC_name = (2''S'',5''R'',6''R'')-6-{[(2''R'')-2-amino-2-(4-hydroxyphenyl)-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-24-carboxylic acid
| image = Amoxicillin.svg
| image2 = Amoxicillin-3D-balls.png
<!--Clinical data-->
| tradename = Amoxil, Tycil, Trimox, others
| Drugs.com = {{drugs.com|monograph|amoxicillin}}
| MedlinePlus = a685001
| pregnancy_AU = A
| pregnancy_US = B
| legal_UK = POM
| legal_US = Rx-only
| routes_of_administration = [[Wiktionary:oral|Oral]], [[intravena]]
<!--Pharmacokinetic data-->
| bioavailability = 95% (pemberian oral)
| metabolism = kurang dari 30% dibiotransformasikan di [[hati]]
| elimination_half-life = 61,3 menit
| excretion = [[ginjal]]
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 26787-78-0
| ATC_prefix = J01
| ATC_suffix = CA04
| ATC_supplemental = {{ATCvet|G51|AA03}}
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 2676
| PubChem = 33613
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB01060
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 31006
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 9EM05410Q9
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07452
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1082
<!--Chemical data-->
| C=16 | H=19 | N=3 | O=5 | S=1
| molecular_weight = 365.4 g/mol
| SMILES = O=C(O)[C@@H]2N3C(=O)[C@@H](NC(=O)[C@@H](c1ccc(O)cc1)N)[C@H]3SC2(C)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = LSQZJLSUYDQPKJ-NJBDSQKTSA-N
}}
'''Amoksisilin''' merupakan [[Antibiotika|antibiotik]] yang digunakan dalam pengobatan berbagai [[infeksi bakteri]].<ref name="AHFS2015">{{Cite web|url=http://www.drugs.com/monograph/amoxicillin.html|title=Amoxicillin|work=The American Society of Health-System Pharmacists|accessdate=1 August 2015}}</ref> Obat ini merupakan lini pertama untuk pengobatan [[Radang telinga tengah|infeksi telinga tengah]]. Obat ini juga dapat digunakan untuk mengobati [[faringitis streptokokus]], [[Radang paru-paru|pneumonia]], [[Selulitis|infeksi kulit]], dan [[infeksi saluran kemih]]. Obat ini diberikan secara per oral.<ref name="AHFS2015">{{Cite web|url=http://www.drugs.com/monograph/amoxicillin.html|title=Amoxicillin|work=The American Society of Health-System Pharmacists|accessdate=1 August 2015}}</ref>
Baris 42 ⟶ 92:
Ruam amoksisilin nonalergi mungkin juga menjadi indikator dari [[Demam kelenjar|mononukleosis menular]]. Beberapa studi yang telah dilakukan menunjukkan sekitar 80-90% dari pasien dengan infeksi [[Virus Epstein-Barr|virus Epstein Barr]] akut yang diobati dengan amoksisilin atau ampisilin menunjukkan gejala ruam.<ref>{{Cite journal|last=Kagan|first=B|year=1977|title=Ampicillin rash|journal=Western Journal of Medicine|volume=126|issue=4|pages=333–335|pmc=1237570|pmid=855325}}</ref><gallery>
File:Amoxicillin rash 3 hours after 17th dose.JPG|
File:Amoxicillin rash 11 hours after 17th dose.JPG|Delapan jam setelah foto pertama,
File:Amoxicillin rash 26 hours after 17th dose.JPG|Pada 23 jam setelah
</gallery>
Baris 75 ⟶ 125:
Amoksisilin merupakan salah satu penisilin semisintetis yang ditemukan oleh ilmuwan Beecham. Paten amoksisilin telah berakhir, dengan demikian sediaan amoksisilin dan co-amoxiclav dijual dengan berbagai nama dagang dan/atau memiliki beberapa sinonim di seluruh dunia, seperti:
{{div col|colwidth=8em}}
*Actimoxi<ref>[http://www.catalog.md/drugs/actimoxi.html Catalog.md: Actimoxi] Linked 2013-12-09</ref>
*Alphamox
*Almox
*Amimox
*AMOXIZIF
*Amocla
*AMK
*Amoksiklav
*Amorion
*Amoxibactin (animal use)
*Amoxibos
*Amoxiclav
*Amoxidal
*Amoxil
*Amoxin<ref>[http://www.ndrugs.com?s=amoxin Amoxin] Linked 2014-07-23</ref>
*Amoxibiotic<ref>[http://www.catalog.md/drugs/amoxibiotic.html Catalog.md: Amoxibiotic] Linked 2013-12-09</ref>
*Amoxicilina
*Amoxidal
*Amoxoral (animal use)
*Apo-Amoxy
*Arsogil<ref>[http://www.aversi.ge/annotations.php?id=73&lang=geo&drug_id=44400 Aversi (Georgia): Arsogil] Linked 2013-12-09</ref>
*Augmentin
*Bactox
*Bioxidona<ref>[http://www.catalog.md/drugs/bioxidona.html Catalog.md: Bioxidona] Linked 2013-12-09</ref>
*Cilamox
*Clamoxyl
*Clavamox
*Clonamox
*Curam
*Dedoxil
*Dispermox
*Duomox
*Defender<ref>[http://www.drugsupdate.com/brand/generic/Amoxicillin%20+%20Clavulanic%20Acid/45673 DrugsUpdate India: Defender from Sac Pharma] Linked 2013-12-09</ref>
*E-Mox<ref>[http://www.eipico.com.eg/PRODUCT.ASP?id1=4&id2=1%20&id4=2 Eipico (Egypt): E-Mox] Linked 2013-12-09</ref>
*Enhancin
*Ezymox<ref>[http://www.drugsupdate.com/brand/generic/Amoxicillin/45866 DrugsUpdate India: Ezymox from Sac Pharma] Linked 2013-12-09</ref>
*Gimalxina
*Geramox
*Hiconcil
*Himox
*Isimoxin<ref>[http://www.catalog.md/drugs/isimoxin.html Catalog.md: Isimoxin] Linked 2013-12-09</ref>
*Klavax
*Klavocin
*Klavox
*Lamoxy
*Largopen
*MOX
*Moxatag
*Moxiclav Duo<ref>{{cite web|url=http://www.aspenpharma.com.au/products/details/index/id/998/product/Moxiclav%20Duo%20500/125|title=Moxiclav Duo 500/125|publisher=}}</ref>
*Moxikem
*Moxilen
*Moxypen
*Moxyvit
*Nobactam
*Novamoxin
*Optamox
*Ospamox
*Pamoxicillin
*Panklav
*Pinamox
*Penamox
*Polymox
*Senox<ref>[http://bioportal.bioontology.org/ontologies/RXNORM?p=classes&conceptid=http%3A%2F%2Fpurl.bioontology.org%2Fontology%2FRXNORM%2F205721 BioPortal: Senox] Linked 2013-12-09</ref>
*Sinacilin
*Skymox<ref>[http://www.pakmedinet.com/trade.php?id=1449 PalMediNet: Skymox] Linked 2013-12-09</ref>
*Spektramox
*Starmox<ref>[http://www.sarthakasia.com/sarthakbiotech/tablets.htm Sarthak Biotech India: Starmox] Linked 2013-12-09</ref>
*Trimox
*Tolodina<ref>[http://www.catalog.md/drugs/tolodina.html Catalog.md: Tolodina] Linked 2013-12-09</ref>
*Tormoxin
*Tyclav<ref>[http://beximco-pharma.com/anti-infectives/5341-tyclav.html Beximco Pharma, Bangladesh: Tyclav] Linked 2013-12-09</ref>
*Unimox
*Vidamox
*Wedemox
*Wymox
*Yucla
*remox
*Zerrsox
*Zimox
*Zoxicillin<ref>[http://www.pakmedinet.com/trade.php?id=1462 PakMediNet (Pakistan): Zoxicillin] Linked 2013-12-09</ref>
{{div col end}}
Nama tanpa rujukan yang spesifik dirujuk dari situs drugs.com.<ref>[http://www.drugs.com/international/amoxicillin.html Drugs.com: Amoxicillin] Linked 2013-12-09</ref>
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