Francis Collins: Perbedaan antara revisi

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== Penelitian genetika ==
AtDi Yale, Collins workedbekerja underdi thebawah direction ofdireksi [[Sherman Weissman]], and in 1984 the two published a paper, "Directional Cloning of DNA Fragments at a Large distance From an Initial Probe: a Circularization Method".<ref>{{cite web |author1=Francis S. Collins |author2=Sherman M. Weissman |title=''Directional cloning of DNA fragments at a large distance from an initial probe: a circularization method'' |publisher=Proc. Natl. Acad. Sci. USA |date=Nov 1984 |url=http://www.pnas.org/content/81/21/6812.full.pdf+html?sid=4509210e-8129-4da3-b99c-dd5829a5a9c2 |accessdate=September 29, 2011}}</ref> The method described was named ''[[chromosome jumping]]'', to emphasize the contrast with an older and much more time-consuming method of copying DNA fragments called ''[[chromosome walking]]''.<ref>{{cite journal |author=Leon. E. Rosenberg |title=''Introductory Speech for Francis S. Collins'' |year=2006 |pmc=1559551 |pmid=16909377 |doi=10.1086/500276 |volume=79 |journal=Am J Hum Genet |pages=419–20}}</ref>
 
Collins joined the [[University of Michigan]] faculty in 1984, rising to the rank of professor in internal medicine and human genetics. His gene-hunting approach, which he named "[[positional cloning]]",<ref>{{cite web |url=https://rowan.biology.ualberta.ca/courses/genet302/uploads/winter11/gane/private/genet302-GW-week3_noQ.pdf |title=Positional cloning of human disease genes: a reversal of scientific priorities |publisher=University of Alberta, Department of Biological Science |accessdate=October 16, 2011}}</ref><ref>{{cite journal |author=Collins F |year=1992 |title=Positional Cloning: Let's not call it reverse anymore |url= |journal=Nature Genetics |volume=1 |issue=1 |pages=3–6 |doi=10.1038/ng0492-3 |pmid=1301996}}</ref> developed into a powerful<ref>{{Cite journal |url=http://www.sciencedirect.com/science/article/pii/0959437X95800425 |title=Positional cloning reaches maturity |last=Nelson |first=David L. |date=Jun 1995 |journal=Curr Opin Genet Dev |accessdate=August 25, 2014 |doi=10.1016/0959-437X(95)80042-5 |pmid=7549422 |volume=5 |issue=3 |pages=298–303}}</ref> component of modern molecular genetics.
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Collins announced his resignation from NHGRI on May 28, 2008, but has continued to maintain an active lab there.<ref>[[Chemical & Engineering News]], Vol. 86 No. 31, August 4, 2008, p. 33, "Francis Collins leaves NIH"</ref>
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== Direktur NIH ==