DPYSL2 telah terbukti memiliki interaksi dengan CRMP1,<ref name="pmid12482610">{{cite journal|last=Leung|first=Thomas|author2=Ng Yvonne|author3=Cheong Albert|author4=Ng Chong Han|author5=Tan Ivan|author6=Hall Christine|author7=Lim Louis|date=Dec 2002|title=p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology|url=|format=|journal=FEBS Lett.|language=|location=Netherlands|publisher=|volume=532|issue=3|pages=445–9|bibcode=|doi=10.1016/S0014-5793(02)03736-5|issn=0014-5793|oclc=|pmid=12482610|id=|accessdate=|laysource=|laydate=|quote=|laysummary=}}</ref>, alpha 1<ref name="pmid12942088">{{cite journal|last=Nishimura|first=Takashi|author2=Fukata Yuko|author3=Kato Katsuhiro|author4=Yamaguchi Tomoya|author5=Matsuura Yoshiharu|author6=Kamiguchi Hiroyuki|author7=Kaibuchi Kozo|date=Sep 2003|title=CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth|url=|format=|journal=Nat. Cell Biol.|language=|location=England|publisher=|volume=5|issue=9|pages=819–26|bibcode=|doi=10.1038/ncb1039|issn=1465-7392|oclc=|pmid=12942088|id=|accessdate=|laysource=|laydate=|quote=|laysummary=}}</ref> dan NUMB.
