''Step Brothers'' menuai beragam ulasan dari para kritikus. Di situs pengumpul ulasan [[Rotten Tomatoes]], film ini menempati rating sebesar 55%, berdasarkan 180 orang pengulas, dengan rata-rata rating 5.5/10.<ref>{{cite web|url=http://www.rottentomatoes.com/m/10009233-step_brothers |title=Step Brothers Movie Reviews, Pictures |publisher=Rotten Tomatoes |date= |accessdate=2015-03-29}}</ref> Sedangkan di website [[Metacritic]], film ini mendapatkan skor 51 dari 100, berdasarkan 33 orang kritikus, yang mengindikasikan bahwa film ini mendapatkan ulasan beragam.<ref>{{cite news|url=http://rogerebert.suntimes.com/apps/pbcs.dll/article?AID=/20080723/REVIEWS/611265921/1001|title= Step Brothers: Review |publisher= rogerebert.com |accessdate=2010-10-19 }}</ref> Film ini dirilis melalui format [[home video]] pada tangal 2 Desember 2008 dengan satu keping yang bertanda ''rated edition'', satu keping lagi bertanda ''unrated edition'' dan dua keping bertanda ''unrated edition''. Film ini berhasil dijual sekitar 3.87 juta keping DVD dan Blu-ray, dengan total penghasilan mencapai $63.7 juta.<ref>{{cite web|url=http://www.the-numbers.com/movies/2008/STEPB-DVD.php |title=Step Brothers - DVD Sales |publisher=Nash Information Services| work=The Numbers |year=2010 |accessdate=2012-09-09}}</ref> Untuk rilis home video, Will Ferrell, John C. Reilly, dan Adam McKay merekam sebuah [[audio commentary|komentar]] dan kebanyakan lagu, bersama [[Jon Brion]].<ref>{{cite web| title= Now with extra farts! 25 1/2 gimmicky DVD commentary tracks | url= http://www.avclub.com/articles/now-with-extra-farts-25-12-gimmicky-dvd-commentary,47021/ | date= November 1, 2010| publisher= [[The A.V. Club]]| accessdate=2012-09-09| quote=But to make it more of a challenge, Ferrell and company sing most of the commentary, accompanied by Jon Brion, who vamps while the boys free-associate about the movie-making process, their characters' off-screen lives, and the exorbitant price they had to pay for a pair of fake testicles. Because it's all spontaneous, the commentary ranges from the inspired to the irritatingly prolonged, but when Ferrell and Reilly really get into a good groove, they're actually funnier than the main feature.}}</ref>
