Perawatannya cukup fleksibel untuk digunakan di rumah sakit, rumah pasien, atau dengan perangkat portabel. [[Tenda oksigen]] dulu digunakan dalam suplementasi oksigen, tetapi sudah diganti dengan penggunaan [[masker oksigen]] atau [[kanula hidung]].<ref name="pmid18540928">{{cite journal|author=Sim MA|author2=Dean P|author3=Kinsella J|author4=Black R|author5=Carter R|author6=Hughes M|display-authors=4|date=2008|title=Performance of oxygen delivery devices when the breathing pattern of respiratory failure is simulated|journal=Anaesthesia|volume=63|issue=9|pages=938–40|doi=10.1111/j.1365-2044.2008.05536.x|pmid=18540928|s2cid=205248111}}</ref>
Obat [[Obat hiperbarik|hiperbarik]] (tekanan tinggi) menggunakan [[ruang oksigen]] khusus untuk meningkatkan [[tekanan parsial]] O<sub>2</sub> di sekitar pasien dan, bila diperlukan, staf medis.<ref name="pmid8931286">{{cite journal|author=Stephenson RN|author2=Mackenzie I|author3=Watt SJ|author4=Ross JA|date=1996|title=Measurement of oxygen concentration in delivery systems used for hyperbaric oxygen therapy|url=http://archive.rubicon-foundation.org/2245|journal=Undersea Hyperb Med|volume=23|issue=3|pages=185–8|pmid=8931286|accessdate=September 22, 2008}}</ref> [[Keracunan karbon monoksida]], [[gas gangrene]], dan [[penyakit dekompresi]] ('tikungan' atau '''the bends''') terkadang disembuhkan dengan terapi ini.<ref>{{cite web|author=Undersea and Hyperbaric Medical Society|authorlink=Undersea and Hyperbaric Medical Society|title=Indications for hyperbaric oxygen therapy|url=http://www.uhms.org/Default.aspx?tabid=270|archiveurl=https://web.archive.org/web/20080912184905/http://www.uhms.org/Default.aspx?tabid=270|archivedate=September 12, 2008|accessdate=September 22, 2008|url-status=dead|df=}}</ref> Meningkatkan konsentrasi O<sub>2</sub> di paru-paru membantu mengeluarkan [[karbon monoksida]] dari kelompok heme [[hemoglobin]].<ref>{{cite web|author=Undersea and Hyperbaric Medical Society|title=Carbon Monoxide|url=http://www.uhms.org/ResourceLibrary/Indications/CarbonMonoxidePoisoning/tabid/272/Default.aspx|archiveurl=https://web.archive.org/web/20080725005744/http://www.uhms.org/ResourceLibrary/Indications/CarbonMonoxidePoisoning/tabid/272/Default.aspx <!--Added by H3llBot-->|archivedate=July 25, 2008|accessdate=September 22, 2008}}</ref><ref name="pmid152331732">{{cite journal|author=Piantadosi CA|date=2004|title=Carbon monoxide poisoning|url=http://archive.rubicon-foundation.org/4002|journal=Undersea Hyperb Med|volume=31|issue=1|pages=167–77|pmid=15233173|accessdate=September 22, 2008}}</ref> Gas oksigen beracun bagi [[bakteri anaerob]] yang menyebabkan gas gangrene. Oleh karena itu, meningkatkan tekanan parsial akan membantu membunuh bakteri anaerob.<ref>{{cite web|author=Undersea and Hyperbaric Medical Society|title=Carbon Monoxide|url=http://www.uhms.org/ResourceLibrary/Indications/CarbonMonoxidePoisoning/tabid/272/Default.aspx|archiveurl=https://web.archive.org/web/20080725005744/http://www.uhms.org/ResourceLibrary/Indications/CarbonMonoxidePoisoning/tabid/272/Default.aspx <!--Added by H3llBot-->|archivedate=July 25, 2008|accessdate=September 22, 2008}}</ref><ref name="pmid15233173">{{cite journal|author=Piantadosi CA|date=2004|title=Carbon monoxide poisoning|url=http://archive.rubicon-foundation.org/4002|journal=Undersea Hyperb Med|volume=31|issue=1|pages=167–77|pmid=15233173|accessdate=September 22, 2008}}</ref> Penyakit dekompresi terjadi pada penyelam yang naik ke atas terlalu cepat setelah menyelam, mengakibatkan gelembung [[Lengai|gas lengai]], sebagian besar terdiri dari [[nitrogen]] dan [[helium]], terbentuk di dalam darah. Meningkatkan tekanan O<sub>2</sub> secepatnya membantu melarutkan kembali gelembung ke dalam darah sehingga kelebihan gas ini dapat dikeluarkan melalui paru-paru.<ref name="ECE5102">[[Oxygen#Reference-idCook1968|Cook & Lauer 1968]], p.510</ref><ref>{{cite web|author=Undersea and Hyperbaric Medical Society|title=Decompression Sickness or Illness and Arterial Gas Embolism|url=http://www.uhms.org/ResourceLibrary/Indications/DecompressionSickness/tabid/275/Default.aspx|archiveurl=https://web.archive.org/web/20080705210353/http://www.uhms.org/ResourceLibrary/Indications/DecompressionSickness/tabid/275/Default.aspx <!--Added by H3llBot-->|archivedate=July 5, 2008|accessdate=September 22, 2008}}</ref><ref>{{cite journal|last=Acott|first=C.|date=1999|title=A brief history of diving and decompression illness|url=http://archive.rubicon-foundation.org/6004|journal=South Pacific Underwater Medicine Society Journal|volume=29|issue=2|accessdate=September 22, 2008}}</ref> Pemberian oksigen normobarik pada konsentrasi tertinggi yang tersedia sering digunakan sebagai pertolongan pertama untuk cedera penyelaman apapun yang mungkin melibatkan pembentukan gelembung gas lengai di [[jaringan]]. Ada dukungan epidemiologis untuk penggunaannya dari studi statistik kasus-kasus yang dicatat dalam [[pangkalan data]] jangka panjang.<ref name="Longphre et al 2007">{{cite journal|last1=Longphre|first1=JM|last2=Denoble|first2=PJ|last3=Moon|first3=RE|last4=Vann|first4=RD|last5=Freiberger|first5=JJ|date=2007|title=First aid normobaric oxygen for the treatment of recreational diving injuries|url=https://pdfs.semanticscholar.org/3c96/eec9b2ae3f25ffc0569f26b7329d5b05e213.pdf|journal=Undersea & Hyperbaric Medicine|volume=34|issue=1|pages=43–49|pmid=17393938|via=Rubicon Research Repository|s2cid=3236557}}</ref><ref name="Emergency O2 for scuba">{{cite web|author=<!--not specified-->|title=Emergency Oxygen for Scuba Diving Injuries|url=https://www.diversalertnetwork.org/training/courses/course_eo2|publisher=Divers Alert Network|location=|accessdate=October 1, 2018}}</ref><ref name="DAN Europe">{{cite web|author=<!--not specified-->|title=Oxygen First Aid for Scuba Diving Injuries|url=https://daneurope.org/web/guest/readarticle;jsessionid=F8EB8916CD93E6A793F9F875BF5FC782?p_p_id=web_content_reading&p_p_lifecycle=0&p_p_mode=view&p_r_p_-1523133153_groupId=10103&p_r_p_-1523133153_articleId=11601&p_r_p_-1523133153_articleVersion=1.0&p_r_p_-1523133153_commaCategories=&p_r_p_-1523133153_commaTags=|publisher=Divers Alert Network Europe|location=|accessdate=October 1, 2018}}</ref>{{clear}}
