Quora didirikan oleh [[Adam D'Angelo]] (mantan ''chief technical officer'' di [[Facebook]]) dan [[Charlie Cheever]]. D'Angelo keluar dari Facebook pada [[Januari 2010]] untuk membuat Quora<ref>{{cite web |url=http://www.businessinsider.com/what-i-learned-from-being-cto-of-facebook-why-i-started-quora-and-this-is-why-gen-y-kicks-ass-at-entrepreneurship-2010-9|title=Why I Quit My CTO Job At Facebook And Started Quora|accessdate=2010-03-29|publisher=Business Insider}}</ref> dan berkata bahwa dia terinspirasi untuk membuat Quora karena dia berpikir bahwa<ref>{{cite web|url=http://bostinnovation.com/2011/02/01/the-mystery-behind-quora-digging-in-with-co-founder-adam-d%E2%80%99angelo/|title=The Mystery Behind Quora|accessdate=2010-03-29|publisher=Boston Innovation|archive-date=2011-03-06|archive-url=https://web.archive.org/web/20110306034237/http://bostinnovation.com/2011/02/01/the-mystery-behind-quora-digging-in-with-co-founder-adam-d%e2%80%99angelo/|dead-url=yes}}</ref> "''banyak sekali situs ''questions-and-answers'' di Internet, tetapi tidak ada yang cukup bagus''". Basis pengguna Quora tumbuh dengan pesat pada bulan [[Desember 2010]].<ref>{{cite web|url=https://techcrunch.com/2011/01/05/quora-surge/|title=Quora Signups Explode|editor-last=Lewenstein|date=2010-11-28|accessdate=2011-01-24}}</ref> Pada [[Maret 2010]], Quora menerima modal dari Benchmark Capital sekaligus memberikan nilai ''start-up'' ini senilai 86 juta [[Dolar Amerika Serikat|dolar]].<ref>{{cite web |url=https://techcrunch.com/2010/03/28/quora-has-the-magic-benchmark-invests-at-86-million-valuation/|title=Benchmark Invests at $86 Million Valuation|accessdate=2010-03-29|publisher=TechCrunch}}</ref>
