'''Dampak [[penyakit koronavirus 2019]]''' sejauh ini berbeda antara laki-laki dan perempuan, baik dalam kontekstingkat pengaruhfatalitas infeksi maupun pengaruhnya ke masyarakat.<ref>{{Cite journal|last=Wenham|first=Clare|last2=Smith|first2=Julia|last3=Morgan|first3=Rosemary|date=2020-03-14|title=COVID-19: the gendered impacts of the outbreak|url=https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30526-2/abstract|journal=The Lancet|language=English|volume=395|issue=10227|pages=846–848|doi=10.1016/S0140-6736(20)30526-2|issn=0140-6736|pmid=32151325}}</ref> Penelitian epidemiologis juga menunjukkan bahwa jenis kelamin, bersama dengan faktor usia dan komorbiditas, berhubungan dengan tingkat keparahan COVID-19.<ref>{{Cite journal|last=Qin|first=Lu|last2=Li|first2=Xiaochen|last3=Shi|first3=Jing|last4=Yu|first4=Muqing|last5=Wang|first5=Ke|last6=Tao|first6=Yu|last7=Zhou|first7=Ying|last8=Zhou|first8=Min|last9=Xu|first9=Shuyun|date=2020|title=Gendered effects on inflammation reaction and outcome of COVID-19 patients in Wuhan|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.26137|journal=Journal of Medical Virology|language=en|volume=92|issue=11|pages=2684–2692|doi=10.1002/jmv.26137|issn=1096-9071|pmc=PMC7300463|pmid=32497297}}</ref> Kematian akibat COVID-19 secara signifikan lebih tinggi pada pria. Rasio antara pria dan wanita pengidap COVID-19 berbeda tipis 1: 0,9.<ref>{{Cite journal|date=2020-10-01|title=Does gender influence clinical expression and disease outcomes in COVID-19? A systematic review and meta-analysis|url=https://www.sciencedirect.com/science/article/pii/S120197122030607X|journal=International Journal of Infectious Diseases|language=en|volume=99|pages=496–504|doi=10.1016/j.ijid.2020.07.076|issn=1201-9712}}</ref>