Beberapa sitokin telah dikembangkan menjadi terapi protein menggunakan teknologi [[DNA rekombinan]].<ref><div>{{Cite Ibelgaufts Horst. [book|last=Zdravkovic|first=Nemanja|last2=Rosic|first2=Mirko|last3=Lutovac|first3=Mitar|last4=Zdravkovic|first4=Vladimir|date=2017-12-20|url=http://www.copewithcytokinesintechopen.decom/cope.cgi?keybooks/physiology-and-pathology-of-immunology/physiology-and-pathology-of-cytokine-commercial-production-and-medical-use|title=recombinant%20cytokinesPhysiology Sitokinand rekombinan]Pathology dalamof SitokinCytokine: &Commercial SelProduction Onlineand PathfinderMedical Encyclopedia Versi 31Use|publisher=InTech|isbn=978-953-51-3691-0|editor-last=Rezaei|editor-first=Nima|language=en|doi=10.4 (Edisi Musim Semi 5772/ Panas 2013) </div>intechopen.72200}}</ref> Sitokin rekombinan yang digunakan sebagai obat pada 2014 meliputi: <ref>Dimiter S. Dimitrov. [https://link.springer.com/protocol/10.1007/978-1-61779-921-1_1 Therapeutic Proteins].Chapter 1 in Therapeutic Proteins: Methods and Protocols, Editors: Vladimir Voynov, Justin A. Caravella. Volume 899 of Methods in Molecular Biology. Springer Science+Business Media, LLC 2012. {{ISBN|978-1-61779-920-4}} (Print) 978-1-61779-921-1 (Online)</ref>
* [[Protein BM|Bone morphogenetic protein]] (BMP), digunakan untuk mengobati kondisi terkait tulang
