'''Penyelidikan terhadap asal-usul COVID-19''' adalah serangkaian misi dan upaya oleh para ilmuwan, pemerintahan, organisasi internasional dan pihak lainnya untuk mencari asal-usul virus yang menyebabkan [[pandemi COVID-19]], [[SARS-CoV-2]] (Sindrom pernapasan akut berat koronavirus 2). Konsensus saintifik menyatakan bahwa virus tersebut adalah sebuah virus [[Zoonosis|zoonotik]] yang timbul dari [[kelelawar]] di lingkungan alam.<ref name="EA-20200317">{{cite news |work=[[EurekAlert!]] |publisher=Scripps Research Institute |title=The COVID-19 coronavirus epidemic has a natural origin, scientists say – Scripps Research's analysis of public genome sequence data from SARS‑CoV‑2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered |url=https://www.eurekalert.org/pub_releases/2020-03/sri-tcc031720.php |date=17 March 2020 |access-date=15 April 2020 }}</ref><ref name="NM-20200317">{{cite journal |vauthors=Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF |display-authors=3 |title=The proximal origin of SARS-CoV-2 |journal=Nature Medicine |volume=26 |issue=4 |pages=450–452 |date=April 2020 |pmid=32284615 |pmc=7095063 |doi=10.1038/s41591-020-0820-9 |doi-access=free}}</ref><ref>{{cite journal |last1=Latinne |first1=Alice |last2=Hu |first2=Ben |last3=Olival |first3=Kevin J. |last4=Zhu |first4=Guangjian |last5=Zhang |first5=Libiao |last6=Li |first6=Hongying |last7=Chmura |first7=Aleksei A. |last8=Field |first8=Hume E. |last9=Zambrana-Torrelio |first9=Carlos |last10=Epstein |first10=Jonathan H. |last11=Li |first11=Bei |last12=Zhang |first12=Wei |last13=Wang |first13=Lin-Fa |last14=Shi |first14=Zheng-Li |last15=Daszak |first15=Peter |display-authors=3 |title=Origin and cross-species transmission of bat coronaviruses in China |journal=Nature Communications |date=25 August 2020 |volume=11 |issue=1 |pages=4235 |doi=10.1038/s41467-020-17687-3 |pmid=32843626 |pmc=7447761 |bibcode=2020NatCo..11.4235L |url=https://www.nature.com/articles/s41467-020-17687-3 |language=en |issn=2041-1723}}</ref>
Otoritas kesehatan dan ilmuwan secara internasional bahwa upaya untuk mencari asal-usul taksonomi dan geografi spesifik [[SARS-CoV-2]] membutuhkan waktu bertahun-tahun, dan hasilnya dapat bersifat tak meyakinkan.<ref name="reut_One_year">{{Cite web|last=Cadell|first=Cate|date=11 December 2020|title=One year on, Wuhan market at epicentre of virus outbreak remains barricaded and empty|url=https://www.reuters.com/article/idUSKBN28L0I0|access-date=19 January 2021|work=[[Reuters]]}}</ref> Sejumlah teori konspirasi [[misinformasi COVID-19|menyatakan soal asal-usul]] virus tersebut.<ref name="CovidMayHave" /><ref name="nofact">{{cite news|last1=Yates|first1=Karen|last2=Pauls|first2=Jeff|title=Online claims that Chinese scientists stole coronavirus from Winnipeg lab have 'no factual basis'|publisher=Canadian Broadcasting Corporation|url=https://www.cbc.ca/news/canada/manitoba/china-coronavirus-online-chatter-conspiracy-1.5442376|url-status=live|access-date=8 February 2020|archive-url=https://web.archive.org/web/20200208134329/https://www.cbc.ca/news/canada/manitoba/china-coronavirus-online-chatter-conspiracy-1.5442376|archive-date=8 February 2020|name-list-style=vanc|time=27 January 2020}}</ref><ref name="20200208economist">{{Cite news|date=8 February 2020|title=China's rulers see the coronavirus as a chance to tighten their grip|work=[[The Economist]]|url=https://www.economist.com/china/2020/02/08/chinas-rulers-see-the-coronavirus-as-a-chance-to-tighten-their-grip|url-status=live|access-date=29 February 2020|archive-url=https://archive.today/20200229034330/https://www.economist.com/china/2020/02/08/chinas-rulers-see-the-coronavirus-as-a-chance-to-tighten-their-grip|archive-date=29 February 2020}}</ref> [[Organisasi Kesehatan Dunia]] menyatakan bahwa asal-usul kebocoran laboratorium untuk virus tersebut "sangatlah tidak mungkin",<ref name="CovidMayHave">{{cite news|date=9 February 2021|title=COVID may have taken 'convoluted path' to Wuhan, WHO team leader says|publisher=Reuters|url=https://www.reuters.com/article/us-health-coronavirus-who-china/covid-may-have-taken-convoluted-path-to-wuhan-who-team-leader-says-idUSKBN2A90BW|vauthors=Horwitz J, Stanway D}}</ref> menyatakan apa yang sebagian besar pakar anggap soal asal-usul alami virus tersebut dan penularan awalnya.
