Helicobacter pylori: Perbedaan antara revisi

=== Genom ===

H. pylori terdiri dari strain-strain yang beragam, dan ratusan [[genom]] telah sepenuhnya [[Pengurutan DNA|disekuensing]].<ref name="Tomb 1997">{{cite journal |vauthors=Tomb JF, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA, Nelson K, Quackenbush J, Zhou L, Kirkness EF, Peterson S, Loftus B, Richardson D, Dodson R, Khalak HG, Glodek A, McKenney K, Fitzegerald LM, Lee N, Adams MD, Hickey EK, Berg DE, Gocayne JD, Utterback TR, Peterson JD, Kelley JM, Cotton MD, Weidman JM, Fujii C, Bowman C, Watthey L, Wallin E, Hayes WS, Borodovsky M, Karp PD, Smith HO, Fraser CM, Venter JC | title = The complete genome sequence of the gastric pathogen ''Helicobacter pylori'' | journal = Nature | volume = 388 | issue = 6642 | pages = 539–47 | date = August 1997 | pmid = 9252185 | doi = 10.1038/41483 }}</ref><ref>{{cite web|url=http://genolist.pasteur.fr/PyloriGene|title= Genome information for the ''H. pylori'' 26695 and J99 strains|publisher=Institut Pasteur|year=2002|format=|work=|accessdate=1 September 2008}}</ref><ref name="genome26695">{{cite web|url=https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=genome&cmd=Retrieve&dopt=Overview&list_uids=128|title=''Helicobacter pylori'' 26695, complete genome|publisher=National Center for Biotechnology Information|format=|work=|accessdate=1 September 2008}}</ref><ref>{{cite web|url=https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=genome&cmd=Retrieve&dopt=Overview&list_uids=139|title=''Helicobacter pylori'' J99, complete genome|publisher=National Center for Biotechnology Information|format=|work=|accessdate=1 September 2008}}</ref><ref name="pmid16788065">{{cite journal |vauthors=Oh JD, Kling-Bäckhed H, Giannakis M, Xu J, Fulton RS, Fulton LA, Cordum HS, Wang C, Elliott G, Edwards J, Mardis ER, Engstrand LG, Gordon JI | title = The complete genome sequence of a chronic atrophic gastritis ''Helicobacter pylori'' strain: Evolution during disease progression | journal = Proc Natl Acad Sci USA | volume = 103 | issue = 26 | pages = 9999–10004 | date = June 2006 | pmid = 16788065 | pmc = 1480403 | doi = 10.1073/pnas.0603784103 | bibcode = 2006PNAS..103.9999O }}</ref><ref>{{Cite journal|last=Vliet|first=Van|last2=M|first2=Arnoud H.|date=1 January 2017|title=Use of pan-genome analysis for the identification of lineage-specific genes of Helicobacter pylori|url=https://academic.oup.com/femsle/article-abstract/364/2/fnw296/2735779/Use-of-pan-genome-analysis-for-the-identification|journal=FEMS Microbiology Letters|volume=364|issue=2|doi=10.1093/femsle/fnw296|issn=0378-1097}}</ref> Genom strain "26695" terdiri dari sekitar 1,7 juta [[pasangan basa]], dengan sekitar 1.576 gen. Pan-genom, yang merupakan gabungan dari 30 strain yang sudah diurutkan, mengkodekan 2.239 famili protein (kelompok ortolog atau ''orthologous groups'', OG). Di antara mereka, 1248 OG dilestarikan di semua 30 strain, dan mewakili ''inti universal''. 991 OG yang tersisa adalah ''genom aksesori'' di mana 277 OG adalah unik (yaitu, OG ada hanya dalam satu strain).<ref>{{Cite journal|last=Uchiyama|first=Ikuo|last2=Albritton|first2=Jacob|last3=Fukuyo|first3=Masaki|last4=Kojima|first4=Kenji K.|last5=Yahara|first5=Koji|last6=Kobayashi|first6=Ichizo|date=9 August 2016|title=A Novel Approach to Helicobacter pylori Pan-Genome Analysis for Identification of Genomic Islands|url=http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159419|journal=PLOS ONE|volume=11|issue=8|pages=e0159419|doi=10.1371/journal.pone.0159419|issn=1932-6203|pmc=4978471|pmid=27504980|bibcode=2016PLoSO..1159419U}}</ref>

 

== Referensi ==