Penderita dirawat dengan [[terapi suportif]], seperti [[terapi cairan]], pemberian oksigen, dan terapi organ vital lain yang terdampak.<ref>{{Cite journal|last=Fisher|first=Dale|last2=Heymann|first2=David|date=2020-02-28|title=Q&A: The novel coronavirus outbreak causing COVID-19|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047369/|journal=BMC Medicine|volume=18|doi=10.1186/s12916-020-01533-w|issn=1741-7015|pmc=7047369|pmid=32106852}}</ref><ref>{{Cite journal|last=Liu|first=Kui|last2=Fang|first2=Yuan-Yuan|last3=Deng|first3=Yan|last4=Liu|first4=Wei|last5=Wang|first5=Mei-Fang|last6=Ma|first6=Jing-Ping|last7=Xiao|first7=Wei|last8=Wang|first8=Ying-Nan|last9=Zhong|first9=Min-Hua|date=2020-05|title=Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province:|url=http://journals.lww.com/10.1097/CM9.0000000000000744|journal=Chinese Medical Journal|language=en|volume=133|issue=9|pages=1025–1031|doi=10.1097/CM9.0000000000000744|issn=0366-6999|pmc=PMC7147277|pmid=32044814}}</ref><ref>{{Cite journal|last=Wang|first=Tianbing|last2=Du|first2=Zhe|last3=Zhu|first3=Fengxue|last4=Cao|first4=Zhaolong|last5=An|first5=Youzhong|last6=Gao|first6=Yan|last7=Jiang|first7=Baoguo|date=2020-03|title=Comorbidities and multi-organ injuries in the treatment of COVID-19|url=https://linkinghub.elsevier.com/retrieve/pii/S0140673620305584|journal=The Lancet|language=en|volume=395|issue=10228|pages=e52|doi=10.1016/S0140-6736(20)30558-4}}</ref> CDC merekomendasikan bagi orang-orang yang mencurigai diri mereka membawa virus agar memakai masker.<ref name=":1" /> [[Oksigenasi membran ekstrakorporeal]] (ECMO) digunakan untuk mengatasi gagal napas, tetapi manfaatnya masih dalam pertimbangan.<ref>{{Cite journal|last=Guan|first=Wei-jie|last2=Ni|first2=Zheng-yi|last3=Hu|first3=Yu|last4=Liang|first4=Wen-hua|last5=Ou|first5=Chun-quan|last6=He|first6=Jian-xing|last7=Liu|first7=Lei|last8=Shan|first8=Hong|last9=Lei|first9=Chun-liang|date=2020-04-30|title=Clinical Characteristics of Coronavirus Disease 2019 in China|url=http://www.nejm.org/doi/10.1056/NEJMoa2002032|journal=New England Journal of Medicine|language=en|volume=382|issue=18|pages=1708–1720|doi=10.1056/NEJMoa2002032|issn=0028-4793|pmc=PMC7092819|pmid=32109013}}</ref><ref>{{Cite journal|last=Guan|first=Wei-jie|last2=Ni|first2=Zheng-yi|last3=Hu|first3=Yu|last4=Liang|first4=Wen-hua|last5=Ou|first5=Chun-quan|last6=He|first6=Jian-xing|last7=Liu|first7=Lei|last8=Shan|first8=Hong|last9=Lei|first9=Chun-liang|date=2020-04-30|title=Clinical Characteristics of Coronavirus Disease 2019 in China|url=http://www.nejm.org/doi/10.1056/NEJMoa2002032|journal=New England Journal of Medicine|language=en|volume=382|issue=18|pages=1708–1720|doi=10.1056/NEJMoa2002032|issn=0028-4793|pmc=PMC7092819|pmid=32109013}}</ref> Higiene diri serta gaya hidup dan diet yang sehat direkomendasikan untuk meningkatkan imunitas.<ref>{{Cite journal|last=Wang|first=Lisheng|last2=Wang|first2=Yiru|last3=Ye|first3=Dawei|last4=Liu|first4=Qingquan|date=2020-03|title=Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence|url=https://linkinghub.elsevier.com/retrieve/pii/S0924857920300984|journal=International Journal of Antimicrobial Agents|language=en|pages=105948|doi=10.1016/j.ijantimicag.2020.105948|pmc=PMC7156162|pmid=32201353}}</ref> Terapi suportif mungkin bermanfaat bagi mereka yang memiliki gejala ringan pada tahap awal infeksi.<ref>{{Cite journal|last=Wang|first=Yixuan|last2=Wang|first2=Yuyi|last3=Chen|first3=Yan|last4=Qin|first4=Qingsong|date=2020-06|title=Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25748|journal=Journal of Medical Virology|language=en|volume=92|issue=6|pages=568–576|doi=10.1002/jmv.25748|issn=0146-6615}}</ref> WHO, [[Komisi Kesehatan Nasional Republik Rakyat Tiongkok|Komisi Kesehatan Nasional Tiongkok]], dan [[Institut Kesehatan Nasional]] Amerika Serikat (NIH) telah menerbitkan rekomendasi perawatan penderita Covid-19 di rumah sakit.<ref>{{Cite web|url=https://www.who.int/publications-detail/clinical-management-of-severe-acute-respiratory-infection-when-novel-coronavirus-(ncov)-infection-is-suspected|title=Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected|website=www.who.int|language=en|access-date=13 Februari 2020}}</ref><ref name=":5">{{Cite web|url=https://www.covid19treatmentguidelines.nih.gov/introduction/|title=COVID-19 Treatment Guidelines: Introduction|last=|first=|date=|website=Institut Kesehatan Nasional AS|language=en|access-date=2020-05-06}}</ref><ref>{{Cite journal|last=Cheng|first=Zhangkai J.|last2=Shan|first2=Jing|date=2020-04|title=2019 Novel coronavirus: where we are and what we know|url=http://link.springer.com/10.1007/s15010-020-01401-y|journal=Infection|language=en|volume=48|issue=2|pages=155–163|doi=10.1007/s15010-020-01401-y|issn=0300-8126|pmc=PMC7095345|pmid=32072569}}</ref>
