[[Berkas:JAL destinations.png|jmpl|Destinasi Japan Airlines]]
Japan Airlines melayani 60 tujuan domestik dan 39 tujuan internasional di [[Asia]], [[Amerika (benua)|Amerika]], [[Eropa]], dan [[Oseania]], tidak termasuk destinasi dengan perjanjian codeshare.<ref name=":2">{{Cite web|date=2020-02-14|title=Number of routes {{!}} About JAL {{!}} JAPAN AIRLINES Corporate Information|url=https://web.archive.org/web/20200214150600/https://www.jal.com/en/outline/route.html|website=web.archive.org|access-date=2023-06-02|archive-date=2020-02-14|archive-url=https://web.archive.org/web/20200214150600/https://www.jal.com/en/outline/route.html|dead-url=unfit}}</ref><ref>{{Cite web|date=2012-07-30|title=All About the JAL Group - Flight|url=https://web.archive.org/web/20120730014101/http://www.jal.com/en/corporate/gaiyo/flight.html|website=web.archive.org|access-date=2023-06-02|archive-date=2012-07-30|archive-url=https://web.archive.org/web/20120730014101/http://www.jal.com/en/corporate/gaiyo/flight.html|dead-url=unfit}}</ref> Hub internasional maskapai ini adalah [[Bandar Udara Internasional Narita|Bandara Internasional Narita]], [[Bandar Udara Internasional Tokyo|Bandara Internasional Haneda]], [[Bandar Udara Internasional Kansai|Bandara Internasional Kansai]], dan [[Bandar Udara Internasional Osaka|Bandara Internasional Itami]]. Japan Airlines dan anak perusahaannya saat ini mengoperasikan lebih dari 4.500 penerbangan internasional dan 26.000 penerbangan domestik setiap bulannya.<ref name=":2" /><ref>{{Cite web|date=2020-02-21|title=Operation Data {{!}} Safety and Flight Information {{!}} JAPAN AIRLINES Corpolate Information|url=https://web.archive.org/web/20200221160930/http://www.jal.com/en/flight/information/|website=web.archive.org|access-date=2023-06-02|archive-date=2020-02-21|archive-url=https://web.archive.org/web/20200221160930/http://www.jal.com/en/flight/information/|dead-url=unfit}}</ref>
