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Kelenjar Skene kadang-kadang disebut sebagai "prostat wanita";<ref>{{Cite journal|author=Zaviacic M, Jakubovská V, Belosovic M, Breza J |title=Ultrastructure of the normal adult human female prostate gland (Skene's gland) |journal=Anat Embryol (Berl) |volume=201 |issue=1 |pages=51–61 |year=2000 |pmid=10603093}}</ref> mereka berada di seluruh uretra dan dapat dirasakan melalui dinding vagina. Namun, penelitian menunjukkan kebanyakan wanita mencapai orgasme hanya melalui stimulasi klitoris.<ref name="O'Connell">{{Cite journal|author=O'Connell HE, Sanjeevan KV, Hutson JM |title=Anatomy of the clitoris |journal=The Journal of Urology |volume=174 |issue=4 Pt 1 |pages=1189–95 |year=2005 |month=October |pmid=16145367 |laysummary=http://news.bbc.co.uk/2/hi/health/5013866.stm |laysource=BBC News |laydate=June 11, 2006 |doi=10.1097/01.ju.0000173639.38898.cd}}</ref><ref name="Frank JE">Frank JE, Mistretta P, Will J. Diagnosis and treatment of female [[sexual dysfunction]]. ''American Family Physician''. (2008);77:635. PMID 18350761</ref><ref name="Clitoris">{{cite web|title='I Want a Better Orgasm!'|publisher=''[[WebMD]]''|accessdate=August 18, 2011|url=http://www.webmd.com/sex/want-better-orgasms|archive-date=2009-01-13|archive-url=https://web.archive.org/web/20090113132443/http://www.webmd.com/sex/want-better-orgasms|dead-url=unfit}}</ref><ref name="Shere Hite">{{cite news|author=[[Shere Hite]]|title=Shere Hite: On female sexuality in the 21st century
|publisher=''[[The Independent]]''|date=April 30, 2006|accessdate=April 10, 2011|url=http://www.independent.co.uk/news/people/profiles/shere-hite-on-female-sexuality-in-the-21st-century-475981.html}}</ref><ref name="www.sexualhealth.com">{{cite web|first=Robert|last=Birch|title=Did you orgasm?|publisher=Sexualhealth.com|date=November 16, 2007|accessdate=April 21, 2010|url=http://www.sexualhealth.com/article/read/women-sexual-health/orgasm/486/|archive-date=2011-07-16|archive-url=https://web.archive.org/web/20110716044630/http://www.sexualhealth.com/article/read/women-sexual-health/orgasm/486/|dead-url=yes}}</ref><ref name="womenshealth.about.com">{{cite web|first=Tracee|last=Cornforth|title=The Clitoral Truth. Interview with author and sexologist Rebecca Chalker|publisher=[[About.com]]|date=July 17, 2009|accessdate=April 21, 2010|url=http://womenshealth.about.com/cs/sexuality/a/clitoraltruthin_2.htm|archive-date=2010-12-03|archive-url=https://web.archive.org/web/20101203102802/http://womenshealth.about.com/cs/sexuality/a/clitoraltruthin_2.htm|dead-url=yes}}</ref> Klitoris mengelilingi vagina agak seperti tapal kuda dan memiliki lebih dari 6.000 serat saraf.<ref name="Chalker">{{cite book|last=Chalker|first=Rebecca|year=2000|title=The Clitoral Truth|url=http://www.sevenstories.com/Book/index.cfm?GCOI=58322100427350|publisher=Seven Seas Press|page=1|isbn=1-58322-473-4|access-date=2012-07-12|archive-date=2011-06-18|archive-url=https://web.archive.org/web/20110618070244/http://www.sevenstories.com/Book/index.cfm?GCOI=58322100427350|dead-url=yes}}</ref> Selain ujung saraf yang hadir dalam anus dan rektum, penjelasan fisiologis mengenai mengapa beberapa wanita menemukan rangsangan anus menyenangkan adalah klitoris memiliki "kaki" yang memperpanjang sepanjang bibir vagina kembali ke anus.<ref name="WWw.goaskalice">{{cite web|title=Doin' the butt—objects in anus?|publisher=[[Go Ask Alice!]]|date=October 7, 1994 (Last Updated/Reviewed on March 26, 2010)|accessdate=April 22, 2010|url=http://www.goaskalice.columbia.edu/0195.html|archive-date=2010-04-01|archive-url=https://web.archive.org/web/20100401114836/http://www.goaskalice.columbia.edu/0195.html|dead-url=yes}}</ref> Titik [[Ernst Gräfenberg|Gräfenberg]], atau G-Spot—daerah kecil di belakang tulang kemaluan perempuan mengelilingi [[uretra]] dan dapat diakses melalui dinding anterior vagina - dianggap memiliki kaki dalam kaitannya dengan klitoris<ref name="O'Connell"/><ref name="Masters and Johnson">{{cite book|last=Federation of Feminist Women’s Health Centers|year=1991|title=A New View of a Woman’s Body|publisher= Feminist Heath Press|page=46|isbn=0-9629945-0-2}}</ref> yang juga dapat diakses melalui penetrasi anal. Stimulasi klitoris, G-Spot, atau keduanya, saat seks anal dapat membantu beberapa wanita untuk menikmati pengalaman itu.<ref name="DeCitore">DeCitore, David. “Arouse Her Anal Ecstasy: [https://www.avrebo.com/category/31/anal The Best Step-by Step Guide that Provides a Pleasurable Path to Anal Sexuality, so She Enjoys Amazing Orgasms and Loves It from Beginning to End].” (2007) ISBN 978-0-615-39914-0 p.176</ref>
 
Seks anal sering digambarkan sebagai "sangat normal" dalam [[pornografi]], tetapi menurut ''[[Go Ask Alice!]]'' dan peneliti lain, terjadi "jauh lebih sering" dari perilaku seksual lainnya.<ref name="Dean and Delvin"/><ref name="WWW.goaskalice">{{cite web|title=Not all gay men have anal sex|publisher=[[Go Ask Alice!]]|date=May 10, 1996 (Last Updated/Reviewed on June 13, 2008)|accessdate=April 26, 2010|url=http://www.goaskalice.columbia.edu/0900.html|archive-date=2011-12-11|archive-url=https://web.archive.org/web/20111211200559/http://www.goaskalice.columbia.edu/0900.html|dead-url=yes}}</ref> Peningkatan aktivitas anal antara pasangan heteroseksual dapat dikaitkan dengan pornografi anal, di mana itu disajikan—dengan debat—sebagai suatu rutinitas dan tidak menyakitkan.<ref name="Dean and Delvin"/> Alasan lain untuk daya tarik seks anal termasuk hubungan dengan dominasi dan [[tabu]].<ref name="dailyuw.com">{{cite web|first=Celia|last=Hunko|title=Anal sex: Let’s get to the bottom of this|publisher=[[The Daily of the University of Washington]]|date=February 6, 2009|accessdate=April 26, 2010|url=http://dailyuw.com/2009/2/6/anal-sex-lets-get-bottom/|archive-date=2010-04-28|archive-url=https://archive.today/20100428073805/http://dailyuw.com/2009/2/6/anal-sex-lets-get-bottom/|dead-url=yes}}</ref> Selain itu, anus itu biasanya lebih ketat dari vagina, yang dapat menghasilkan kenikmatan sentuhan yang lebih besar bagi manusia melalui penisnya.<ref name="Boellstorff">{{cite book|author =Tom Boellstorff|title=The gay archipelago: sexuality and nation in Indonesia|isbn = 0691123349, 9780691123349|publisher=Princeton University Press|year=2005|page=282|accessdate=March 12, 2011|url=