Artikel baru tentang topik farmasi yang masih memerlukan tambahan dan pengembangan. Artikel ini merupakan terjemahan wikipedia bahasa Inggris masih perlu ditinjau ulang juga disesuaikan dengan padanan bahasa Indonesia
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<!-- Legal data -->|legal_status=rx-only|licence_US=|licence_EU=<!-- Pharmacokinetic data -->|bioavailability=33–55%<ref>Micromedex® 2010 – DRUGDEX Evaluations (Cyclobenzaprine Hydrochloride)</ref><ref>{{cite web |url = http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=18929 |title = Cyclobenzaprine Hydrochloride Tablets USP Revised: April 2005 Rx only |work = nih.gov |access-date = 1 October 2016 |archive-date = 21 April 2016 |archive-url = https://web.archive.org/web/20160421183526/https://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=18929 |url-status = live }}</ref>|protein_bound=93%|metabolism=Major: [[CYP3A4]], [[CYP1A2]]; Minor: [[CYP2D6]], [[Demethylation|N-demethylation]]<ref name="autogen1">{{cite web|url=https://www.amrix.com/Content/Pdf/prescribing-information.pdf|date=May 2016|title=AMR40470 (Amrix) Prescribing Information|author=Teva Pharmaceuticals USA, Inc|access-date=2 February 2017|archive-date=22 December 2016|archive-url=https://web.archive.org/web/20161222030052/http://www.amrix.com/Content/Pdf/prescribing-information.pdf|url-status=live}}</ref>|elimination_half-life=32 hours (range 8–37 hours)<ref>{{citeweb|urlname=https://www.amrix.com/Content/Pdf/prescribing-information.pdf|date=May"autogen1" 2016|title=AMR40470 (Amrix) Prescribing Information|author=Teva Pharmaceuticals USA, Inc|access-date=2 February 2017|archive-date=22 December 2016|archive-url=https://web.archive.org/web/20161222030052/http://www.amrix.com/Content/Pdf/prescribing-information.pdf|url-status=live}}</ref>|excretion=Kidney
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'''Siklobenzaprin ('''''Cyclobenzaprine)'' adalah obat yang digunakan untuk mengatasi [[Spasmofili|kejang otot]] yang disebabkan keadaan muskuloskeletal yang terjadi spontan. <ref name="AHFS2018">{{Cite web|title=Cyclobenzaprine Monograph for Professionals|url=https://www.drugs.com/monograph/cyclobenzaprine.html|website=Drugs.com|publisher=AHFS|archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html|archive-date=23 December 2018|access-date=22 December 2018|url-status=live}}</ref> Obat ini tidak memiliki manfaat pada kondisi [[Lumpuh otak|Cerebral Palsy]] . <ref name="AHFS2018">{{citeweb |title=Cyclobenzaprine Monograph for Professionals |url=https://www.drugs.com/monograph/cyclobenzaprine.html |website=Drugs.com |publisher=AHFS |access-date=22 December 2018 |archive-date=23 December 2018 |archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html |url-status=live }}</ref> Rute minum obat secara oral. <ref name="AHFS2018">{{citeweb |title=Cyclobenzaprine Monograph for Professionals |url=https://www.drugs.com/monograph/cyclobenzaprine.html |website=Drugs.com |publisher=AHFS |access-date=22 December 2018 |archive-date=23 December 2018 |archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html |url-status=live }}</ref> Tidak direkomendasikan untuk pengobatan lebih dari beberapa minggu. <ref name="AHFS2018">{{citeweb |title=Cyclobenzaprine Monograph for Professionals |url=https://www.drugs.com/monograph/cyclobenzaprine.html |website=Drugs.com |publisher=AHFS |access-date=22 December 2018 |archive-date=23 December 2018 |archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html |url-status=live }}</ref>
Efek samping pada obat ini secara umum kejadian [[sakit kepala]], rasa lelah, pusing, dan mulut kering. <ref name="AHFS2018">{{Citeweb|title=Cyclobenzaprine Monograph for Professionals|url=https://www.drugs.com/monograph/cyclobenzaprine.html|website=Drugs.com|publisher=AHFS|archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html|archive-date=23 December 2018|access-date=22 December 2018|url-status=live}}<cite class="citation web cs1" data-ve-ignore="true">[https://www.drugs.com/monograph/cyclobenzaprine.html "Cyclobenzaprine Monograph for Professionals"]. </cite></ref> Efek samping serius pada obat ini mungkin timbulnya [[aritmia]] . <ref name="AHFS2018">{{citeweb |title=Cyclobenzaprine Monograph for Professionals |url=https://www.drugs.com/monograph/cyclobenzaprine.html |website=Drugs.com |publisher=AHFS |access-date=22 December 2018 |archive-date=23 December 2018 |archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html |url-status=live }}</ref> Tidak ada bukti berbahaya pada penggunaan ibu hamil, namun hal ini masih belum diteliti dengan baik pada populasi yang besar. <ref name="AHFS2018">{{citeweb |title=Cyclobenzaprine Monograph for Professionals |url=https://www.drugs.com/monograph/cyclobenzaprine.html |website=Drugs.com |publisher=AHFS |access-date=22 December 2018 |archive-date=23 December 2018 |archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html |url-status=live }}</ref> Obat ini tidak direkomendarikan digunakan bersama dengan obat golongan inhibitor MAO . <ref name="AHFS2018">{{citeweb |title=Cyclobenzaprine Monograph for Professionals |url=https://www.drugs.com/monograph/cyclobenzaprine.html |website=Drugs.com |publisher=AHFS |access-date=22 December 2018 |archive-date=23 December 2018 |archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html |url-status=live }}</ref> Mekanisme kerja pada obat ini belum diketahui secara jelas. <ref name="AHFS2018">{{citeweb |title=Cyclobenzaprine Monograph for Professionals |url=https://www.drugs.com/monograph/cyclobenzaprine.html |website=Drugs.com |publisher=AHFS |access-date=22 December 2018 |archive-date=23 December 2018 |archive-url=https://web.archive.org/web/20181223073516/https://www.drugs.com/monograph/cyclobenzaprine.html |url-status=live }}</ref>
