Zolpidem: Perbedaan antara revisi

Konten dihapus Konten ditambahkan
WanaraLima (bicara | kontrib)
Dibuat dengan menerjemahkan halaman "User:Mr. Ibrahem/Zolpidem"
Tag: halaman dengan galat kutipan tanpa kategori [ * ] Terjemahan Konten Terjemahan Konten v2
 
WanaraLima (bicara | kontrib)
Artikel baru tentang topik farmasi yang masih memerlukan tambahan dan pengembangan. Artikel ini merupakan terjemahan wikipedia bahasa Inggris masih perlu ditinjau ulang juga disesuaikan dengan padanan bahasa Indonesia
Tag: halaman dengan galat kutipan VisualEditor
Baris 19:
Efek samping yang umum dalam penggunaan obat ini seperti: rasa kantuk di siang hari, sakit kepala, rasa mual, dan muncul diare. <ref name="AHFS2018">{{Cite web|title=Zolpidem Tartrate|url=https://www.drugs.com/monograph/zolpidem-tartrate.html|publisher=The American Society of Health-System Pharmacists|access-date=15 March 2018|archive-date=16 March 2018|archive-url=https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html|url-status=live}}<cite class="citation web cs1" data-ve-ignore="true">[https://www.drugs.com/monograph/zolpidem-tartrate.html "Zolpidem Tartrate"]. The American Society of Health-System Pharmacists. [https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html Archived] from the original on 16 March 2018<span class="reference-accessdate">. Retrieved <span class="nowrap">15 March</span> 2018</span>.</cite></ref> Efek samping lainnya yang bisa muncul pada penggunaan obat ini yakni gangguan masalah ingatan, [[halusinasi]], dan [[Penyalahgunaan obat|penyalahgunaan]] . <ref name="AFP2017">{{Cite journal| vauthors = Matheson E, Hainer BL | title = Insomnia: Pharmacologic Therapy | journal = American Family Physician | volume = 96 | issue = 1 | pages = 29–35 | date = July 2017 | pmid = 28671376 | url = https://www.aafp.org/afp/2017/0701/p29.html | access-date = 2018-08-18 | archive-date = 2018-08-19 | archive-url = https://web.archive.org/web/20180819051215/https://www.aafp.org/afp/2017/0701/p29.html | url-status = live }}<cite class="citation journal cs1" data-ve-ignore="true" id="CITEREFMathesonHainer2017">Matheson E, Hainer BL (July 2017). [https://www.aafp.org/afp/2017/0701/p29.html "Insomnia: Pharmacologic Therapy"]. ''American Family Physician''. <b>96</b> (1): 29–35. [[PMID (identifier)|PMID]]&nbsp;[https://pubmed.ncbi.nlm.nih.gov/28671376 28671376]. [https://web.archive.org/web/20180819051215/https://www.aafp.org/afp/2017/0701/p29.html Archived] from the original on 2018-08-19<span class="reference-accessdate">. Retrieved <span class="nowrap">2018-08-18</span></span>.</cite></ref> Dosis pada zolpidem yang direkomendasikan mengalami penurunan pada tahun 2013 hal ini karena, bisa menyebabkan gangguan pada hari esoknya. <ref name="FDA2013">{{Cite web|title=Drug Safety and Availability - FDA Drug Safety Communication: FDA approves new label changes and dosing for zolpidem products and a recommendation to avoid driving the day after using Ambien CR|url=https://www.fda.gov/drugs/drugsafety/ucm352085.htm|website=www.fda.gov|archive-url=https://web.archive.org/web/20180406065123/https://www.fda.gov/drugs/drugsafety/ucm352085.htm|archive-date=2018-04-06|access-date=2018-03-15|url-status=live}}</ref> Penggunaan zolpidem tidak direkomendasikan untuk mengemudi kendaraan tidak direkomendasikan juga pada pengguna dosis yang lebih tinggi atau penggunaan jangka panjang. <ref name="FDA2013">{{cite web|title=Drug Safety and Availability - FDA Drug Safety Communication: FDA approves new label changes and dosing for zolpidem products and a recommendation to avoid driving the day after using Ambien CR|url=https://www.fda.gov/drugs/drugsafety/ucm352085.htm|website=www.fda.gov|access-date=2018-03-15|archive-date=2018-04-06|archive-url=https://web.archive.org/web/20180406065123/https://www.fda.gov/drugs/drugsafety/ucm352085.htm|url-status=live}}</ref> Penggunaan obat flumazenil bisa membalikkan efek dari zolpidem, juga penggunaannya hanya untuk [[Pengobatan simtomatik|perawatan suportif]] yang direkomendasikan jika terjadi overdosis. <ref name="Forensic2013">{{Cite journal|date=June 2013|title=The clinical and forensic toxicology of Z-drugs|journal=Journal of Medical Toxicology|volume=9|issue=2|pages=155–62|doi=10.1007/s13181-013-0292-0|pmc=3657020|pmid=23404347|vauthors=Gunja N}}</ref>
 
Zolpidem merupakan golongan obat nonbenzodiazepine Z yang memiliki fungsi sebagai obat penenang dan dipakai sebagai [[obat tidur]] . <ref name="AHFS2018">{{Cite web|title=Zolpidem Tartrate|url=https://www.drugs.com/monograph/zolpidem-tartrate.html|publisher=The American Society of Health-System Pharmacists|access-date=15 March 2018|archive-date=16 March 2018|archive-url=https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html|url-status=live}}<cite class="citation web cs1" data-ve-ignore="true">[https://www.drugs.com/monograph/zolpidem-tartrate.html "Zolpidem Tartrate"]. The American Society of Health-System Pharmacists. [https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html Archived] from the original on 16 March 2018<span class="reference-accessdate">. Retrieved <span class="nowrap">15 March</span> 2018</span>.</cite></ref> <ref name="Z2013">{{Cite journal|last=Gunja|first=N|date=June 2013|title=The clinical and forensic toxicology of Z-drugs|journal=Journal of Medical Toxicology|volume=9|issue=2|pages=155–62|doi=10.1007/s13181-013-0292-0|pmc=3657020|pmid=23404347}}</ref> Zolpidem bekerja di agonis reseptor GABA <nowiki><sub id="mwPg">A</sub></nowiki> dari kelas imidazopyridine . <ref name="AHFS2018">{{cite web|title=Zolpidem Tartrate|url=https://www.drugs.com/monograph/zolpidem-tartrate.html|publisher=The American Society of Health-System Pharmacists|access-date=15 March 2018|archive-date=16 March 2018|archive-url=https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html|url-status=live}}</ref> Obat zolpidem memiliki mekanisme kerja dengan cara meningkatkan efek [[Asam gama-aminobutirat|GABA]] di [[sistem saraf pusat]] dengan mengikat reseptor GABA <sub>A</sub> di lokasi yang sama seperti golongan [[benzodiazepin]] . <ref name="AHFS2018">{{cite web|title=Zolpidem Tartrate|url=https://www.drugs.com/monograph/zolpidem-tartrate.html|publisher=The American Society of Health-System Pharmacists|access-date=15 March 2018|archive-date=16 March 2018|archive-url=https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html|url-status=live}}</ref> Zolpidem memiliki [[Waktu paruh biologis|waktu paruh]] sekitar 2-3 jam. <ref name="AHFS2018">{{cite web|title=Zolpidem Tartrate|url=https://www.drugs.com/monograph/zolpidem-tartrate.html|publisher=The American Society of Health-System Pharmacists|access-date=15 March 2018|archive-date=16 March 2018|archive-url=https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html|url-status=live}}</ref> Waktu paruh bisa saja meningkat jika digunakan pada mereka yang memiliki gangguan liver . <ref name="AHFS2018">{{cite web|title=Zolpidem Tartrate|url=https://www.drugs.com/monograph/zolpidem-tartrate.html|publisher=The American Society of Health-System Pharmacists|access-date=15 March 2018|archive-date=16 March 2018|archive-url=https://web.archive.org/web/20180316023759/https://www.drugs.com/monograph/zolpidem-tartrate.html|url-status=live}}</ref>
 
== Referensi ==
<references />{{Farmasi-stub}}
[[Kategori:Obat]]
[[Kategori:Farmasi]]