Spektinomisin: Perbedaan antara revisi
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{{Short description|Antibiotik}}
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 464405974
| IUPAC_name = (1''R'',3''S'',5''R'',8''R'',10''S'',11''S'',12''S'',13''R'',14''S'')-8,12,14-trihydroxy-5-methyl-11,13-''bis''(methylamino)-2,4,9-trioxatricyclo[8.4.0.0<sup>3,8</sup>]tetradecan-7-one
| image = Spectinomycin.svg
<!--Clinical data-->
| tradename = Trobicin
| pregnancy_US = B
| legal_US_comment = not available
| routes_of_administration = Injeksi intramuskular
<!--Pharmacokinetic data-->
| bioavailability =
| protein_bound =
| metabolism =
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 1695-77-8
| ATC_prefix = J01
| ATC_suffix = XX04
| ATC_supplemental =
| PubChem = 15541
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB00919
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 14785
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 93AKI1U6QF
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D08526
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 9215
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1167
<!--Chemical data-->
| C=14 | H=24 | N=2 | O=7
| smiles = O=C1[C@@]2(O[C@@H]3[C@@H](NC)[C@@H](O)[C@@H](NC)[C@H](O)[C@H]3O[C@@H]2O[C@@H](C1)C)O
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = UNFWWIHTNXNPBV-WXKVUWSESA-N
| synonyms = <small>(2''R'',4a''R'',5a''R'',6''S'',7''S'',8''R'',9''S'',9a''R'',10a''S'')-4a,7,9-trihydroxy-2-methyl-6,8-''bis''(methylamino)decahydro-4''H''-pyrano[2,3-''b''][1,4]benzodioxin-4-one</small> , SPT/SPE/SC/SP<ref>{{cite web |title=Antibiotic abbreviations list |url=https://microbiologie-clinique.com/antibiotic-family-abbreviation.html |access-date=22 June 2023}}</ref>
| melting_point = 184
| melting_high = 194
}}
Spektinomisin (''spectinomycin'') adalah [[antibiotik]] dari golongan [[aminosiklitol]] (''aminocyclitol'') yang berguna dalam pengobatan [[infeksi]] bakteri ''[[Neisseria gonorrhoeae]]''.<ref name=":0">{{Cite web|title=Spectinomycin|url=https://go.drugbank.com/drugs/DB00919|website=go.drugbank.com|language=en|access-date=2024-04-03}}</ref><ref>{{Cite web|title=Spectinomycin Uses, Side Effects & Warnings|url=https://www.drugs.com/mtm/spectinomycin.html|website=Drugs.com|language=en|access-date=2024-04-03}}</ref> Antibiotik ini diberikan melalui suntikan ke dalam otot (injeksi intramuskular). Spektinomisim umumnya digunakan dalam pengobatan [[uretritis gonore]] akut dan [[proktitis]] pada pria, serta [[servisitis gonore]] akut dan proktitis pada wanita.<ref name=":0" />
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