Sefuroksim: Perbedaan antara revisi
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Baris 1:
{{Short description|Antibiotic medication}}
{{Use dmy dates|date=October 2021}}
{{Drugbox
| Watchedfields = changed
| verifiedrevid = 460025245
| IUPAC_name = (6''R'',7''R'')-3-{[(Aminokarbonil)oksi]metil}-7-{[(2''Z'')-2-(2-furil)-2-(metoksiimino)acetil]amino}-8-okso-5-tia-1-azabisiklo[4.2.0]okt-2-ena-2-asam karboksilat
| image = Cefuroxime.svg
| alt = Skeletal formula of cefuroxime
| image2 = Cefuroxime-3D-spacefill.png
| alt2 = Ball-and-stick model of the cefuroxime molecule
<!--Clinical data-->
| tradename = Zinacef, Ceftin, Furacia, dll
| Drugs.com = {{drugs.com|monograph|cefuroxime-sodium}}
| MedlinePlus = a601206
| DailyMedID = Cefuroxime
| pregnancy_category = B
| legal_AU = S4
| legal_status = Rx-only
| routes_of_administration = [[Penyuntikan intraotot|Intramuskular]], intravena, oral
| class = [[Sefalosporin]] generasi pertama
<!--Pharmacokinetic data-->
| bioavailability = 37% saat perut kosong, hingga 52% jika diminum setelah makan
| elimination_half-life = 80 menit
| excretion = Urine 66–100% tidak berubah
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 55268-75-2
| ATC_prefix = J01
| ATC_suffix = DC02
| ATC_supplemental = {{ATC|S01|AA27}} {{ATCvet|J51|DC02}}
| PubChem = 5361202
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB01112
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4514699
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = O1R9FJ93ED
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D00262
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 466
<!--Chemical data-->
| C=16 | H=16 | N=4 | O=8 | S=1
| smiles = O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)C(=N\OC)\c3occc3)COC(=O)N)C(=O)O
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9+/t10-,14-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = JFPVXVDWJQMJEE-SWWZKJRFSA-N
}}
'''Sefuroksim''' merupakan [[antibiotik]] [[sefalosporin]]<ref>{{Cite book| vauthors = Katzung B |title=Basic & Clinical Pharmacology|publisher=McGraw Hill|year=2018|pages=803}}</ref> generasi kedua yang digunakan untuk mengobati dan mencegah sejumlah infeksi bakteri termasuk [[Radang paru-paru|pneumonia]], [[meningitis]], [[radang telinga tengah]], [[sepsis]], [[infeksi saluran kemih]], dan [[penyakit Lyme]]. Obat ini digunakan melalui [[Oral (rute pemberian obat)|mulut]], atau di[[infus|suntik]]kan ke pembuluh darah atau [[Penyuntikan intraotot|otot]].<ref name=AHFS2019>{{cite web |title=Cefuroxime Sodium Monograph for Professionals |url=https://www.drugs.com/monograph/cefuroxime-sodium.html |website=Drugs.com |publisher=American Society of Health-System Pharmacists |access-date=22 March 2019 }}</ref>
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