Pirasetam: Perbedaan antara revisi

Konten dihapus Konten ditambahkan
Muhammad Anas Sidik (bicara | kontrib)
Tidak ada ringkasan suntingan
Tag: halaman dengan galat kutipan Suntingan perangkat seluler Suntingan peramban seluler Suntingan seluler lanjutan
Muhammad Anas Sidik (bicara | kontrib)
Tidak ada ringkasan suntingan
Tag: halaman dengan galat kutipan Suntingan perangkat seluler Suntingan peramban seluler Suntingan seluler lanjutan
Baris 1:
{{Drugbox
| Watchedfields = changed
| verifiedrevid = 464207742
| IUPAC_name = 2-(2-Oksopirolidin-1-il)asetamida
| image = Piracetam.svg
| width = 150
| image2 = Piracetam ball-and-stick.png
| alt =
| caption = <!--Clinical data-->
| tradename = Breinox, Dinagen, Lucetam, Nootropil, Nootropyl, Oikamid, Piracetam, & masih banyak lagi
| Drugs.com = {{Drugs.com|international|piracetam}}
| legal_AU = S4
| legal_CA = Unscheduled
| legal_UK = POM
| legal_US = Unapproved "New Drug" (as defined by 21 U.S. Code § 321(p)(1)). Use in [[dietary supplement]]s, [[food]], or [[medicine]] is unlawful; otherwise uncontrolled.
| legal_US_comment = <ref name=drugbank>{{cite web | url = https://www.drugbank.ca/drugs/DB09210 | title = Piracetam | work = DrugBank database }}</ref>)
| routes_of_administration = Oral, parenteral, atau vaporisasi
 
<!--Pharmacokinetic data-->| bioavailability = ~100%
| protein_bound =
| metabolism =
| elimination_half-life = 4–5 [[jam]]
| excretion = Urin
| onset = Swiftly following administration. Food delays time to peak concentration by 1.5&nbsp;[[hour|h]] approximately to 2–3&nbsp;h since dosing.<ref>[http://www.e-lactancia.org/media/papers/Piracetam-DS-UCB2013.pdf Leaflet of Piracetam].</ref>
 
<!--Identifiers-->| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 7491-74-9
| ATC_prefix = N06
| ATC_suffix = BX03
| PubChem = 4843
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4677
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ZH516LNZ10
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D01914
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 36715
| IUPHAR_ligand = 4288
| DrugBank = DB09210
 
<!--Chemical data-->| C = 6
| H = 10
| N = 2
| O = 2
| smiles = O=C1N(CC(=O)N)CCC1
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = GMZVRMREEHBGGF-UHFFFAOYSA-N
| melting_point = 152
}}
 
 
'''Pirasetam''' merupakan obat yang mempunyai khasiat pada gangguan kognitif, vertigo, mioklonus kortikal, [[disleksia]], dan [[anemia]] sel sabit. Berbagai sumber berbeda mengenai kegunaannya untuk [[demensia]].<ref name="(eMC) 2017"/><ref name=Winblad2005/><ref name=Flic2001>{{cite journal | vauthors = Flicker L, Grimley Evans G | title = Piracetam for dementia or cognitive impairment | journal = The Cochrane Database of Systematic Reviews | issue = 2 | pages = CD001011 | date = 2001 | pmid = 11405971 | doi = 10.1002/14651858.CD001011 }}</ref> Pirasetam dijual sebagai obat di banyak negara Eropa. Penjualan pirasetam tidak ilegal di Amerika Serikat, meskipun tidak diatur atau disetujui oleh [[Badan Pengawas Obat dan Makanan Amerika Serikat|FDA]], sehingga dijual secara legal hanya untuk keperluan penelitian.<ref name=JAMA2019>{{cite journal | vauthors = Cohen PA, Zakharevich I, Gerona R | title = Presence of Piracetam in Cognitive Enhancement Dietary Supplements | journal = JAMA Internal Medicine | volume = 180 | issue = 3 | pages = 458–459 | date = March 2020 | pmid = 31764936 | pmc = 6902196 | doi = 10.1001/jamainternmed.2019.5507 }}</ref>