'''Nyeri ulu hati''' (Bahasa Inggris: '''''heartburn'''''),<ref>{{Cite web|last=|first=|date=|title=Heartburn (Nyeri Ulu Hati)|url=https://www.halodoc.com/kesehatan/heartburn-nyeri-ulu-hati|website=halodoc.com|language=id-ID|access-date=14 Juni 2024}}</ref> (Bahasa Inggris: '''''heartburn'''''), juga dikenal sebagai '''pirosis''', '''kardialgia''', atau '''gangguan asam pencernaan''',<ref>{{cite web | url=http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/ger-and-gerd-in-adults/Pages/overview.aspx | title=Gastroesophageal Reflux (GER) and Gastroesophageal Reflux Disease (GERD) in Adults | work=The National Institute of Diabetes and Digestive and Kidney Diseases | access-date=2015-07-24 | url-status=live | archive-url=https://web.archive.org/web/20150725032223/http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/ger-and-gerd-in-adults/Pages/overview.aspx | archive-date=2015-07-25 }}</ref> adalah sensasi terbakar di [[dada]] bagian tengah atau perut bagian tengah atas.<ref name=":2">{{DorlandsDict|four/000047500|heartburn}}</ref><ref name="ReferenceA">{{cite book |title=Differential diagnosis in primary care |publisher=Wolters Kluwer Health/Lippincott Williams & Wilkins |location=Philadelphia |year=2008 |pages=211 |isbn=978-0-7817-6812-2 }}</ref><ref>{{cite web|url=http://www.merriam-webster.com/medical/pyrosis|title=Pyrosis Medical Definition - Merriam-Webster Medical Dictionary|work=merriam-webster.com|access-date=24 July 2015|url-status=live|archive-url=https://web.archive.org/web/20150725013215/http://www.merriam-webster.com/medical/pyrosis|archive-date=25 July 2015}}</ref> Nyeri ulu hati biasanya disebabkan oleh regurgitasi [[asam lambung]] (''gastric reflux'') ke [[Esofagus|kerongkongan]]. Ini merupakan gejala utama [[penyakit refluks gastroesofagus]] (GERD).<ref>{{Cite web|title=Heartburn|url=https://www.nlm.nih.gov/cgi/mesh/2005/MB_cgi?mode&term=heartburn|url-status=live|archive-url=https://web.archive.org/web/20160312161013/http://www.nlm.nih.gov/cgi/mesh/2005/MB_cgi?mode&term=heartburn|archive-date=2016-03-12|access-date=2015-07-24|work=National Library of Medicine}}</ref>
Gambaran umum lainnya untuk sakit maag (selain rasa terbakar) adalah bersendawa, mual, diremas, ditusuk, atau sensasi tertekan di dada. Nyeri sering kali timbul di dada (tepat di belakang tulang dada) dan bisa menjalar ke leher, tenggorokan, atau sudut lengan. Karena dada merupakan rumah bagi organ-organ penting lainnya selain kerongkongan (termasuk jantung dan paru-paru), tidak semua gejala sakit maag bersifat esofagus.<ref name=":4">{{cite book | vauthors = Johnson K, Ghassemzadeh S | chapter = Chest Pain |date=2024 | title = StatPearls | chapter-url = http://www.ncbi.nlm.nih.gov/books/NBK470557/ |access-date=2024-04-28 |place=Treasure Island (FL) |publisher=StatPearls Publishing |pmid=29262011 }}</ref>