'''Simulasi kehidupan''' (atau '''permainan kehidupan buatan''')<ref name="fundamentals">{{cite book|last=Rollings|first=Andrew|author2=Ernest Adams |title=Fundamentals of Game Design|publisher=Prentice Hall|year=2006|location=|url=http://wps.prenhall.com/bp_gamedev_1/54/14053/3597646.cw/index.html}}
</ref> adalah sebuah subgenre [[permainan video simulasi]] dimana pemain menghidupkan atau mengendalikan satu atau lebih bentuk kehidupan virtual. Sebuah permainan simulasi kehidupan dapat melibatkan "individual dan hubungan atau dapat merupakan simulasi ekosistem".<ref name="fundamentals"/> Beberapa contoh permainan video yang bergenre simulasi kehidupan diantranya: ''Tamagotchi'' (1996),<ref>{{Cite web|title=Artificial Life and Puzzle Games {{!}} Ghostarchive|url=https://wps.prenhall.com/bp_gamedev_1/54/14053/3597646.cw/index.html|website=ghostarchive.org|access-date=2022-08-21|archive-date=2021-10-02|archive-url=https://ghostarchive.org/archive/20211002141019/https://wps.prenhall.com/bp_gamedev_1/54/14053/3597646.cw/index.html|dead-url=unfit}}</ref> ''Creatures'' (1996), ''Odell'' (1986), ''WolfQuest'' (2013), ''Evolution: The Game of Intelligent Life'' (1997), ''Spore'' (2008), ''The Sims'' (2000),<ref>{{Cite web|title=CNN - Chatpage - Sci-Tech / Computing {{!}} Ghostarchive|url=http://edition.cnn.com/chat/transcripts/2000/1/wright/index.html|website=ghostarchive.org|access-date=2022-08-21|archive-date=2021-10-09|archive-url=https://ghostarchive.org/archive/20211009151010/http://edition.cnn.com/chat/transcripts/2000/1/wright/index.html|dead-url=unfit}}</ref> dan ''Life Computer People'' (2000).<ref>{{Cite web|title=Little Computer People • Eurogamer.net {{!}} Ghostarchive|url=https://www.eurogamer.net/articles/little-computer-people-review|website=ghostarchive.org|access-date=2022-08-21|archive-date=2021-10-09|archive-url=https://ghostarchive.org/archive/20211009151020/https://www.eurogamer.net/articles/little-computer-people-review|dead-url=unfit}}</ref>