Enfluran: Perbedaan antara revisi
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==Farmakologi==
Mekanisme kerja anestesi umum yang tepat belum dijelaskan.<ref>{{cite web | vauthors = Perkins B | date = 7 February 2005 | work = Scientific American | url=http://www.scientificamerican.com/article/how-does-anesthesia-work/ | title=How does anesthesia work?}}</ref> Enfluran bertindak sebagai modulator alosterik positif dari GABA<sub>A</sub>,<ref>{{cite journal | vauthors = Wakamori M, Ikemoto Y, Akaike N | title = Effects of two volatile anesthetics and a volatile convulsant on the excitatory and inhibitory amino acid responses in dissociated CNS neurons of the rat | journal = Journal of Neurophysiology | volume = 66 | issue = 6 | pages = 2014–2021 | date = December 1991 | pmid = 1667416 | doi = 10.1152/jn.1991.66.6.2014 }}</ref><ref>{{cite journal | vauthors = Jones MV, Brooks PA, Harrison NL | title = Enhancement of gamma-aminobutyric acid-activated Cl- currents in cultured rat hippocampal neurones by three volatile anaesthetics | journal = The Journal of Physiology | volume = 449 | pages = 279–293 | date = April 1992 | pmid = 1326046 | pmc = 1176079 | doi = 10.1113/jphysiol.1992.sp019086 }}</ref><ref>{{cite journal | vauthors = Krasowski MD, Harrison NL | title = The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations | journal = British Journal of Pharmacology | volume = 129 | issue = 4 | pages = 731–743 | date = February 2000 | pmid = 10683198 | pmc = 1571881 | doi = 10.1038/sj.bjp.0703087 }}</ref><ref>{{cite journal | vauthors = Lin LH, Chen LL, Zirrolli JA, Harris RA | title = General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 263 | issue = 2 | pages = 569–578 | date = November 1992 | pmid = 1331405 }}</ref> reseptor glisin, dan 5-HT<sub>3</sub>,<ref name="PerryAshton2002">{{cite book| vauthors = Perry EK, Ashton H, Young AH |title=Neurochemistry of Consciousness: Neurotransmitters in Mind |url= https://books.google.com/books?id=3o2fCDDoSuUC&pg=PA154 |year=2002|publisher=John Benjamins Publishing|isbn=978-1-58811-124-1|pages=154–}}</ref><ref name="CoteLerman2013">{{cite book| vauthors = Cote CJ, Lerman J, Anderson BJ |title=A Practice of Anesthesia for Infants and Children: Expert Consult - Online and Print|url=https://books.google.com/books?id=MAXTnQStL0cC&pg=PA499|year=2013|publisher=Elsevier Health Sciences|isbn=978-1-4377-2792-0|pages=499–}}</ref> dan sebagai modulator alosterik negatif dari reseptor AMPA, kainat, dan NMDA,<ref name="CoteLerman2013" /><ref name="BarashCullen2013">{{cite book| vauthors = Barash P, Cullen BF, Stoelting RK, Cahalan M, Stock CM, Ortega R |title=Clinical Anesthesia, 7e: Print + Ebook with Multimedia|url=https://books.google.com/books?id=exygUxEuxnIC&pg=PA116|date=7 February 2013|publisher=Lippincott Williams & Wilkins|isbn=978-1-4698-3027-8|pages=116–}}</ref><ref name="pmid7681790">{{cite journal | vauthors = Lin LH, Chen LL, Harris RA | title = Enflurane inhibits NMDA, AMPA, and kainate-induced currents in Xenopus oocytes expressing mouse and human brain mRNA | journal = FASEB Journal | volume = 7 | issue = 5 | pages = 479–485 | date = March 1993 | pmid = 7681790 | doi = 10.1096/fasebj.7.5.7681790 | doi-access = free | s2cid = 1050582 }}</ref> serta reseptor asetilkolin nikotinik.<ref name="PerryAshton2002" />
==Efek samping==
==Keselamatan kerja==
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