Benzatropin: Perbedaan antara revisi
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Baris 73:
==Efek samping==
Berikut ini terutama adalah antikolinergik:
*[[Xerostomia|Mulut kering]]
*Penglihatan kabur
*Perubahan kognitif
*Mengantuk
*[[<Sembelit]]
*[[Retensi urin]]
*[[Takikardia]]
*[[Anoreksia]]
*[[Delirium]] berat dan [[halusinasi]] (dalam kasus [[overdosis]])
Meskipun beberapa penelitian menunjukkan bahwa penggunaan antikolinergik meningkatkan risiko ''tardive dyskinesia'' (efek samping jangka panjang dari antipsikotik),<ref>{{cite journal | vauthors = Kane JM, Smith JM | title = Tardive dyskinesia: prevalence and risk factors, 1959 to 1979 | journal = Archives of General Psychiatry | volume = 39 | issue = 4 | pages = 473–481 | date = April 1982 | pmid = 6121548 | doi = 10.1001/archpsyc.1982.04290040069010 | s2cid = 10194153 }}</ref><ref name="pmid11534539">{{cite journal | vauthors = Wszola BA, Newell KM, Sprague RL | title = Risk factors for tardive dyskinesia in a large population of youths and adults | journal = Experimental and Clinical Psychopharmacology | volume = 9 | issue = 3 | pages = 285–296 | date = August 2001 | pmid = 11534539 | doi = 10.1037/1064-1297.9.3.285 }}</ref> penelitian lain tidak menemukan hubungan antara paparan antikolinergik dan risiko mengembangkan ''tardive dyskinesia'',<ref name="pmid9546009">{{cite journal | vauthors = van Harten PN, Hoek HW, Matroos GE, Koeter M, Kahn RS | title = Intermittent neuroleptic treatment and risk for tardive dyskinesia: Curaçao Extrapyramidal Syndromes Study III | journal = The American Journal of Psychiatry | volume = 155 | issue = 4 | pages = 565–567 | date = April 1998 | pmid = 9546009 | doi = 10.1176/ajp.155.4.565 }}</ref> meskipun gejalanya dapat memburuk.<ref>{{cite journal | vauthors = Yassa R | title = Tardive dyskinesia and anticholinergic drugs. A critical review of the literature | journal = L'Encéphale | volume = 14 Spec No | issue = Spec No | pages = 233–239 | date = September 1988 | pmid = 3063514 }}</ref>
Obat yang menurunkan transmisi kolinergik dapat mengganggu penyimpanan informasi baru ke dalam memori jangka panjang. Agen antikolinergik juga dapat mengganggu persepsi waktu.<ref name="pmid2661606">{{cite journal | vauthors = Gelenberg AJ, Van Putten T, Lavori PW, Wojcik JD, Falk WE, Marder S, Galvin-Nadeau M, Spring B, Mohs RC, Brotman AW | title = Anticholinergic effects on memory: benztropine versus amantadine | journal = Journal of Clinical Psychopharmacology | volume = 9 | issue = 3 | pages = 180–185 | date = June 1989 | pmid = 2661606 | doi = 10.1097/00004714-198906000-00004 | s2cid = 27308127 }}</ref>
==Farmakologi==
==Kegunaan pada hewan==
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