'''Isokonazol''' adalah obat [[antijamur]] [[azola]] dan dapat menghambat bakteri [[gram-positif]].<ref name=Veraldi2013>{{cite journal | vauthors = Veraldi S | title = Isoconazole nitrate: a unique broad-spectrum antimicrobial azole effective in the treatment of dermatomycoses, both as monotherapy and in combination with corticosteroids | journal = Mycoses | volume = 56 | issue = Suppl 1 | pages = 3–15 | date = May 2013 | pmid = 23574019 | doi = 10.1111/myc.12054 | s2cid = 1881151 }}</ref><ref>{{cite book |title=[[The Merck Index]] |chapter=Isoconazole |edition=12th |page=5176 | isbn = 0-911910-12-3 | veditors = Budavari S | date = 1996 | vauthors = Budavari S, O'Neil M, Smith A, Heckelman P, Obenchain J }}</ref> Untuk infeksi kaki dan vagina, isokonazol memiliki efektivitas yang sama dengan [[klotrimazol]].<ref name=Oyeka1992>{{cite journal | vauthors = Oyeka CA, Gugnani HC | title = Isoconazole nitrate versus clotrimazole in foot and nail infections due to Hendersonula toruloidea, Scytalidium hyalinum and dermatophytes | journal = Mycoses | volume = 35 | issue = 11–12 | pages = 357–361 | year = 1992 | pmid = 1302811 | doi = 10.1111/j.1439-0507.1992.tb00894.x | s2cid = 6764090 }}</ref><ref name=Cohen1984>{{cite journal | vauthors = Cohen L | title = Single dose treatment of vaginal candidosis: comparison of clotrimazole and isoconazole | journal = The British Journal of Venereal Diseases | volume = 60 | issue = 1 | pages = 42–44 | date = February 1984 | pmid = 6365236 | pmc = 1046268 | doi = 10.1136/sti.60.1.42 }}</ref> Isokonazol nitrat dapat digunakan dalam kombinasi dengan [[kortikosteroid]] [[diflukortolon]] untuk meningkatkan [[bioavailabilitas]]nya.<ref name=Veraldi2013/> Obat ini dipatenkan pada tahun 1968 dan disetujui untuk penggunaan medis pada tahun 1979.<ref name=Fischer2006>{{cite book | vauthors = Fischer J, Ganellin CR |author-link2=C. Robin Ganellin |date=2006 |title=Analogue-based Drug Discovery |language=en |publisher=John Wiley & Sons |isbn=9783527607495 |page=502 |url=https://books.google.com/books?id=FjKfqkaKkAAC&pg=PA502}}</ref>